Institution
Manipal University
Education•Manipal, Karnataka, India•
About: Manipal University is a education organization based out in Manipal, Karnataka, India. It is known for research contribution in the topics: Population & Medicine. The organization has 9525 authors who have published 11207 publications receiving 110687 citations.
Topics: Population, Medicine, Computer science, Health care, Cancer
Papers published on a yearly basis
Papers
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TL;DR: The strength of the composite material depends on the type of application, right combination of fiber to resin, length, type, orientation of fibers, use of anchors and form (sheet, plate). Temperature is an important factor which is taken into consideration as discussed by the authors.
46 citations
TL;DR: This study uses an integrated transcriptomic and proteomic strategy to validate and improve the existing zebrafish genome annotation, and reports the identification of 157 novel protein-coding genes.
46 citations
TL;DR: This study comprehensively reports 386 novel proteins that have important potential as biomarker candidates for future research into personalized medicine and diagnostics aimed towards improving visual health.
Abstract: The aqueous humor is a colorless, transparent fluid that fills the anterior chamber of the eye. It plays an important role in maintaining the intraocular pressure and providing nourishment to the lens and cornea. The constitution of the aqueous humor is controlled by the blood-aqueous barrier. Though this ocular fluid has been extensively studied, its role in ocular physiology is still not completely understood. In this study, aqueous humor samples were collected from 250 patients undergoing cataract surgery, subjected to multiple fractionation strategies and analyzed on a Fourier transform LTQ-Orbitrap Velos mass spectrometer. In all, we identified 763 proteins, of which 386 have been identified for the first time in this study. Sorbitol dehydrogenase (SORD), filensin (BFSP1), and phakinin (BFSP2) are some of the proteins that have not been previously reported in the aqueous humor. Gene Ontology analysis revealed 35% of the identified proteins to be extracellular, with a majority of them involved in cell communication and signal transduction. This study comprehensively reports 386 novel proteins that have important potential as biomarker candidates for future research into personalized medicine and diagnostics aimed towards improving visual health.
46 citations
TL;DR: This study shows the possible exploration for drug repurposing using computer-aided docking tools and the potential roles of tipiracil and aprepitant, which can be explored further in the treatment of COVID-19.
46 citations
Journal Article•
TL;DR: The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.
Abstract: Inclusion complex of plumbagin was prepared with betacyclodextrin employing neutralization method. The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.
46 citations
Authors
Showing all 9740 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| John J.V. McMurray | 178 | 1389 | 184502 |
| Ashok Kumar | 151 | 5654 | 164086 |
| Zhanhu Guo | 128 | 886 | 53378 |
| Vijay P. Singh | 106 | 1699 | 55831 |
| Michael Walsh | 102 | 963 | 42231 |
| Akhilesh Pandey | 100 | 529 | 53741 |
| Vivekanand Jha | 94 | 958 | 85734 |
| Manuel Hidalgo | 92 | 538 | 41330 |
| Madhukar Pai | 89 | 522 | 33349 |
| Ravi Kumar | 82 | 571 | 37722 |
| Vijay V. Kakkar | 60 | 470 | 17731 |
| G. Münzenberg | 58 | 336 | 9837 |
| Abhishek Sharma | 52 | 426 | 9715 |
| Ramesh R. Bhonde | 49 | 223 | 8397 |
| Chandra P. Sharma | 48 | 325 | 12100 |