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Institution

Manipal University

EducationManipal, Karnataka, India
About: Manipal University is a education organization based out in Manipal, Karnataka, India. It is known for research contribution in the topics: Population & Health care. The organization has 9525 authors who have published 11207 publications receiving 110687 citations.


Papers
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Journal ArticleDOI
TL;DR: The study illustrates that autophagy is essential for human osteoblast survival and mineralization, and osteoblasts are susceptible to apoptosis due to reduced autophage during differentiation, and estrogen, via upregulation of RAB3GAP1, promotesAutophagy in osteoblast during differentiation thereby increasing their survival and Mineralization capacity.

40 citations

Journal ArticleDOI
02 May 2017-eLife
TL;DR: Urgent action is needed if the authors are committed to ending the TB epidemic, which means raising the level of ambition, embracing innovation, increasing financial investments, addressing implementation gaps, and ensuring that new technologies reach those who need them to survive.
Abstract: The past decade has seen the emergence of new diagnostics and drugs for tuberculosis, a disease that kills over 1.8 million people each year. However, these new tools are yet to reach scale, and access remains a major challenge for patients in low and middle income countries. Urgent action is needed if we are committed to ending the TB epidemic. This means raising the level of ambition, embracing innovation, increasing financial investments, addressing implementation gaps, and ensuring that new technologies reach those who need them to survive. Otherwise, the promise of innovative technologies will never be realized.

40 citations

Journal ArticleDOI
TL;DR: The ability of binary amorphous technology to simultaneously overcome both the BCS barriers i.e. solubility and permeability is demonstrated.

40 citations

Journal ArticleDOI
TL;DR: Multisensory stimulation appears to have a beneficial effect on the tonal maturation in preterm infants, however, further studies are warranted to investigate the long-term effects of multisENSory stimulation on neurodevelopmental outcome in pre term infants.
Abstract: To investigate the effect of Auditory, Tactile, Visual and Vestibular stimulus (ATVV) on neuromotor development in preterm infants. Fifty preterm infants born at 28–36 wk with a birth weight ranging from 1,000–2,000 g were recruited for the study. They were block randomized into a control group (n = 25) and study group (n = 25). New Ballard score was used for the baseline measurement of neuromaturity in both groups. In neonatal intensive care unit (NICU), the study group received multisensory stimulation for 12 min per session, 5 sessions per wk along with routine NICU care either from 33 wk corrected gestational age for infants born at 28–32 wk or from 48 h of birth for infants born at 33–36 wk until discharge from the hospital. The control group received the routine NICU care. At term age the preterm infants were assessed using Infant Neurological International Battery (INFANIB) and the groups were compared using independent t test. The multisensory stimulated infants showed higher neuromotor score (p = 0.001) compared to the control group. The french angle components of INFANIB including heel to ear (p = 0.016) and popliteal angle (p = 0.001) were statistically significant between the groups. Multisensory stimulation appears to have a beneficial effect on the tonal maturation in preterm infants. However, further studies are warranted to investigate the long-term effects of multisensory stimulation on neurodevelopmental outcome in preterm infants.

40 citations

Journal ArticleDOI
TL;DR: For the first time, data is provided showing that AGE induces several cell signaling cascades, like NF-κB, PKC, ERK, and MAPK, that are involved in autophagy and simultaneously help with the accumulation of lipid droplets that are not cleared effectively by autophagic clearance, therefore causing obesity.

40 citations


Authors

Showing all 9740 results

NameH-indexPapersCitations
John J.V. McMurray1781389184502
Ashok Kumar1515654164086
Zhanhu Guo12888653378
Vijay P. Singh106169955831
Michael Walsh10296342231
Akhilesh Pandey10052953741
Vivekanand Jha9495885734
Manuel Hidalgo9253841330
Madhukar Pai8952233349
Ravi Kumar8257137722
Vijay V. Kakkar6047017731
G. Münzenberg583369837
Abhishek Sharma524269715
Ramesh R. Bhonde492238397
Chandra P. Sharma4832512100
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023102
2022280
20212,150
20201,821
20191,422
20181,083