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Institution

Manipal University

EducationManipal, Karnataka, India
About: Manipal University is a education organization based out in Manipal, Karnataka, India. It is known for research contribution in the topics: Population & Health care. The organization has 9525 authors who have published 11207 publications receiving 110687 citations.


Papers
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Journal ArticleDOI
TL;DR: These newly synthesized compounds were characterized by elemental analyses, I.R, NMR and Mass spectral studies, and many of the molecules were found to be potent.

117 citations

Journal ArticleDOI
TL;DR: This paper proposes a new certificate-based “lightweight access control and key agreement protocol in the IoT environment, called LACKA-IoT,” that utilizes the elliptic curve cryptography (ECC) along with the “collision-resistant one-way cryptographic hash function.”
Abstract: For secure communication between any two neighboring sensing devices on the Internet of Things (IoT) environment, it is essential to design a secure device access control and key agreement protocol, in which the two phases, namely, “node authentication” and “key agreement” are involved. While the node authentication allows two sensing devices to authenticate each other using their own pre-loaded secret credentials in memory, the key agreement phase permits to establish a secret key between them if the mutual authentication is successful. In this paper, we propose a new certificate-based “lightweight access control and key agreement protocol in the IoT environment, called LACKA-IoT,” that utilizes the elliptic curve cryptography (ECC) along with the “collision-resistant one-way cryptographic hash function.” Through a detailed security analysis using the formal security under the “Real-Or-Random (ROR) model,” informal (non-mathematical) security analysis, and formal security verification using the broadly used “Automated Validation of Internet Security Protocols and Applications (AVISPA)” tool, we show that the LACKA-IoT can protect various known attacks that are needed for a secure device access control mechanism in the IoT. Furthermore, through a comparative study of the LACKA-IoT and other relevant schemes, we show that there is a better tradeoff among the security and functionality features and communication and computational costs of the LACKA-IoT as compared to other schemes. Finally, the “practical demonstration using the NS2 simulation” has been carried out on the LACKA-IoT to measure various network parameters.

116 citations

Journal ArticleDOI
TL;DR: In this article, a Laser Induced Breakdown Spectroscopy (LIBS) technique has been applied for the identification of four widely used plastics, polyethylene terephthalate (PET), high-density polyethylenes (PE), polypropylene (PP) and polystyrene (PS), whose recycling is required from commercial and biosafety points of view.
Abstract: A Laser Induced Breakdown Spectroscopy (LIBS) technique has been applied for the identification of four widely used plastics, polyethylene terephthalate (PET), high-density polyethylene (PE), polypropylene (PP) and polystyrene (PS), whose recycling is required from commercial and biosafety points of view. The 3rd harmonic (355 nm) nanosecond pulse from an Nd:YAG laser is used to create plasma on the sample surface and identification of the type of the plastic is derived from the plasma emission. Principal Component Analysis (PCA) of the LIBS spectra is employed for the classification of plastics. Distinct methods have been used, apart from principal components of PCA, to further confirm our results. Statistical parameters, viz., Mahalanobis distance (M-distance) and spectral residuals were used for decisive match/no match test which provided successful classification of plastics. Receiver Operating Characteristic (ROC) and Youden's index analyses were carried out to obtain the diagnostic threshold for classification of all four classes of plastics. Sensitivity, specificity, predictive values and discriminative accuracy of the classification tests based on the optimum threshold were calculated. This proves the analytical predictive capabilities of the LIBS technique for plastic identification and classification. The technique of LIBS, in future, can be routinely used in field applications such as plastic waste sorting and recycling.

115 citations

Journal ArticleDOI
TL;DR: In this article, a co-processed mixture of micro-crystalline cellulose and mannitol was used for fast dissolving tablets, where the powder and compression properties of the composite particles were evaluated.
Abstract: Co-processed particles of microcrystalline cellulose and mannitol were fabricated by spray drying technique to be used as a direct compression excipient in fast dissolving tablet formulation. Microcrystalline cellulose passed through sieve no.80, having a volumetric mean diameter (d 50 ) of 28.35 µm, was used to form composite particles with powdered mannitol which was previously passed through sieve no. 80, in various mixing ratios. The composite particles were evaluated for their powder and compression properties. An increase in the microcrystalline cellulose proportion imparted greater compressibility to the composite particles, but the flowability of these mixtures was decreased. Although microcrystalline cellulose and mannitol have been extensively used in the formulation of fast dissolving tablets, the non-wetting property of the hard compact central core may delay the disintegration time. Optimized co-processed formulation containing mannitol and microcrystalline cellulose in the ratio of 1.25:1 was found to have optimized powder and compressibility characteristics with fast disintegrating property (<15 s). Photomicrographs have shown that the mannitol crystals are fine and uniformly distributed in the microcrystalline matrix in spray dried form compared to physical mixture of the same combination. The fast disintegration may be due to the partial amorphization and formation of submicron particles of mannitol. These results indicated that improved fast dissolving tablets could be prepared by the co-processed mixture of microcrystalline cellulose and mannitol. Finally fast dissolving tablets of glipizide were prepared by blending with other excipients and compressed into tablets. Sensory study on disintegration time and mouth feel attributes ranked the present formulation based on grittiness, chalkiness and overall preference as the best.

114 citations

Journal ArticleDOI
TL;DR: The structural analysis of cation-pi interaction forming residues shows that Lys, Trp, and Tyr prefer to be in the binding site of protein-DNA complexes, and the accessible surface areas of cationside interaction forming cationic residues are significantly less than that of other residues.

114 citations


Authors

Showing all 9740 results

NameH-indexPapersCitations
John J.V. McMurray1781389184502
Ashok Kumar1515654164086
Zhanhu Guo12888653378
Vijay P. Singh106169955831
Michael Walsh10296342231
Akhilesh Pandey10052953741
Vivekanand Jha9495885734
Manuel Hidalgo9253841330
Madhukar Pai8952233349
Ravi Kumar8257137722
Vijay V. Kakkar6047017731
G. Münzenberg583369837
Abhishek Sharma524269715
Ramesh R. Bhonde492238397
Chandra P. Sharma4832512100
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023102
2022280
20212,150
20201,821
20191,422
20181,083