Manipal University

About: Manipal University is a education organization based out in Manipal, Karnataka, India. It is known for research contribution in the topics: Population & Health care. The organization has 9525 authors who have published 11207 publications receiving 110687 citations.

Design of RF energy harvesting system for energizing low power devices

Abstract: Electromagnetic energy harvesting holds a promising future for energizing low power electronic devices in wireless communication circuits. This article presents an RF energy harvesting system that can harvest energy from the ambient surroundings at the downlink radio frequency range of GSM-900 band. The harvesting system is aimed to provide an alternative source of energy for energizing low power devices. The system design consists of three modules: a single wideband 377› E-shaped patch antenna, a pi matching network and a 7-stage voltage doubler circuit. These three modules were fabricated on a single printed circuit board. The antenna and Pi matching network have been optimized through electromagnetic simulation software, Agilent ADS 2009 environment. The uniqueness of the system lies in the partial ground plane and the alignment of induced electric fleld for maximum current ∞ow in the antenna that maximizes the captured RF energy. The design and simulation of the voltage doubler circuit were performed using Multisim software. All the three modules were integrated and fabricated on a double sided FR 4 printed circuit board. The DC voltage obtained from the harvester system in the fleld test at an approximate distance of 50m from GSM cell tower was 2.9V. This voltage was enough to power the STLM20 temperature sensor.

Effect of four vehicles on the pH of calcium hydroxide and the release of calcium ion

Abstract: Nonsetting calcium hydroxide pastes are commonly used in endodontic practice. The desired therapeutic effect of such a paste is in part dependent on the dissociation of calcium hydroxide into hydroxy ion and calcium ion. This in turn is influenced by the vehicle used to make the paste. This investigation attempts to quantitatively estimate the release of hydroxyl ion and calcium ion from pastes made by using distilled water, normal saline solution, camphorated monochlorophenol and also an experimental vehicle, propylene glycol. The results of this study indicate that propylene glycol induces the most favorable release characteristics of the two ionic species.

Suture-related complications following keratoplasty: a 5-year retrospective study.

Abstract: Purpose To study the incidence of suture-related complications following penetrating keratoplasty (PK) and their effect on the success of corneal grafting. Methods The records of 332 patients receiving 361 grafts in 1993 and 1994 were reviewed, and suture-related complications were recorded. These complications were divided into five groups: suture erosions, infiltrates at the suture sites, infectious keratitis, loose sutures with imminent wound dehiscence, and wound dehiscence after suture removal. Results Occurrence rates were suture erosions, 10.8%; infiltrates, 9.4%; infectious keratitis related to sutures, 3.3%; loose sutures with imminent wound separation in need of surgical repair, 8.3%; and wound dehiscence following suture removal, 2.4%. Conclusions Suture-related complications frequently occur after PK. Infectious keratitis and wound separations needing surgical repair may lead to loss of best-corrected visual acuity due to scarring, induced allograft reactions, and/or increased astigmatism. Recommendations for post-PK suture management are proposed.

Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells.

Abstract: Administration of natural or synthetic agents to inhibit, delay, block, or reverse the initiation and promotional events associated with carcinogenesis opens a new avenue for cancer prevention and treatment to reduce cancer morbidity and mortality. Eugenol, a potential chemopreventive agent, is a component of clove and several other spices such as basil, cinnamon, and bay leaves. A number of reports have shown that eugenol possesses antiseptic, analgesic, antibacterial, and anticancer properties. The present study was undertaken to evaluate the chemopreventive potential of eugenol alone and in combination with a chemotherapeutic agent such as gemcitabine. Eugenol showed dose-dependent selective cytotoxicity toward HeLa cells in comparison to normal cells, pointing to its safe cytotoxicity profile. A combination of eugenol and gemcitabine induced growth inhibition and apoptosis at lower concentrations, compared with the individual drugs. The analysis of the data using a combination index showed combination index values of <1 indicating strong synergistic interaction. The combination thus may enhance the efficacy of gemcitabine at lower doses and minimize the toxicity on normal cells. In addition, the expression analysis of genes involved in apoptosis and inflammation revealed significant downregulation of Bcl-2, COX-2, and IL-1β on treatment with eugenol. Thus, the results suggest that eugenol exerts its anticancer activities via apoptosis induction and anti-inflammatory properties and also provide the first evidence demonstrating synergism between eugenol and gemcitabine, which may enhance the therapeutic index of prevention and/or treatment of cervical cancer.