Marche Polytechnic University

About: Marche Polytechnic University is a education organization based out in Ancona, Italy. It is known for research contribution in the topics: Population & Prostate cancer. The organization has 5905 authors who have published 15769 publications receiving 382286 citations. The organization is also known as: Universitá Politecnica delle Marche & Universita Politecnica delle Marche.

The Healthy Effects of Strawberry Polyphenols: Which Strategy behind Antioxidant Capacity?

Abstract: Current evidence indicates that the consumption of strawberries, a natural source of a wide range of nutritive and bioactive compounds, is associated with the prevention and improvement of chronic-degenerative diseases. Studies involving cells and animals provide evidence on the anti-inflammatory, anticarcinogenic and antiproliferative activity of the strawberry. Epidemiological and clinical studies demonstrate that its acute consumption increases plasma antioxidant capacity, improves circulating inflammatory markers and ameliorates postprandial glycemic response. At the same time, a protracted intake reduces chronic inflammation and improves plasma lipid profile, supporting cardiovascular health, especially in individuals with increased risk for metabolic syndrome. To explain these beneficial effects, much attention has been paid in the past to the antioxidant properties of strawberry polyphenols. However, recent research has shown that their biological and functional activities are related not only to the antioxidant capacity but also to the modulation of many cellular pathways involved in metabolism, survival, proliferation, and antioxidant defenses. The aim of this review is to update and discuss the molecular and cellular mechanisms proposed in recent studies to elucidate the healthy effects of strawberry polyphenols against the most common chronic diseases, such as cancer, cardiovascular diseases, metabolic syndrome, and inflammation.

Spectral domain optical coherence tomography findings in patients with acute syphilitic posterior placoid chorioretinopathy

Abstract: Purpose:To describe the appearance of acute syphilitic posterior placoid chorioretinitis, a rare ocular manifestation of syphilis, on spectral domain optical coherence tomography (SD OCT) both before and after treatment.Methods:Ophthalmic examination and imaging studies of 30 eyes of 19 confirmed ca

Insights into the cybotactic nematic phase of bent-core molecules

Abstract: We present X-ray diffraction evidence for clusters exhibiting a skewed cybotactic supramolecular structure in the nematic phase of the butyloxy-phenyl diester, ODBP-Ph-OC4, a bent core mesogenic diester of the nonlinear diol 2,5-bis-(p-hydroxyphenyl)-1,3,4-oxadiazole (ODBP). The temperature dependence of the off-meridional four-spot pattern shows that the tilt angle in the cybotactic clusters changes with temperature. The correlation lengths exhibit no evidence of critical behavior but there is no underlying smectic C phase in ODBP-Ph-OC4. The tilted cybotactic clusters persist throughout the 85 °C wide nematic phase, and even remain evident in the supercooled nematic. This inherently biaxial supramolecular structure—clusters of stratified and tilted mesogens—embedded in an otherwise translationally disordered nematic host medium may account for the NMR biaxiality observed in nematic phases of ODBP mesogens.