scispace - formally typeset
Search or ask a question
Institution

McGill University

EducationMontreal, Quebec, Canada
About: McGill University is a education organization based out in Montreal, Quebec, Canada. It is known for research contribution in the topics: Population & Context (language use). The organization has 72688 authors who have published 162565 publications receiving 6966523 citations. The organization is also known as: Royal institution of advanced learning & University of McGill College.


Papers
More filters
Journal ArticleDOI
TL;DR: These guidelines provide a roadmap for developing integrated, evidence-based, and patient-centered protocols for preventing and treating pain, agitation, and delirium in critically ill patients.
Abstract: Objective:To revise the “Clinical Practice Guidelines for the Sustained Use of Sedatives and Analgesics in the Critically Ill Adult” published in Critical Care Medicine in 2002.Methods:The American College of Critical Care Medicine assembled a 20-person, multidisciplinary, multi-institutional task f

3,005 citations

Book
01 Jun 1990
TL;DR: Auditory Scene Analysis as discussed by the authors addresses the problem of hearing complex auditory environments, using a series of creative analogies to describe the process required of the human auditory system as it analyzes mixtures of sounds to recover descriptions of individual sounds.
Abstract: Auditory Scene Analysis addresses the problem of hearing complex auditory environments, using a series of creative analogies to describe the process required of the human auditory system as it analyzes mixtures of sounds to recover descriptions of individual sounds. In a unified and comprehensive way, Bregman establishes a theoretical framework that integrates his findings with an unusually wide range of previous research in psychoacoustics, speech perception, music theory and composition, and computer modeling.

2,968 citations

Journal ArticleDOI
22 Feb 2007-Nature
TL;DR: Four loci containing variants that confer type 2 diabetes risk are identified and constitute proof of principle for the genome-wide approach to the elucidation of complex genetic traits.
Abstract: Type 2 diabetes mellitus results from the interaction of environmental factors with a combination of genetic variants, most of which were hitherto unknown. A systematic search for these variants wa ...

2,945 citations

Journal ArticleDOI
01 Dec 2006-Science
TL;DR: A highly significant association is found between Crohn's disease and the IL23R gene on chromosome 1p31, which encodes a subunit of the receptor for the proinflammatory cytokine interleukin-23, which prioritize this signaling pathway as a therapeutic target in inflammatory bowel disease.
Abstract: The inflammatory bowel diseases Crohn's disease and ulcerative colitis are common, chronic disorders that cause abdominal pain, diarrhea, and gastrointestinal bleeding. To identify genetic factors that might contribute to these disorders, we performed a genome-wide association study. We found a highly significant association between Crohn's disease and the IL23R gene on chromosome 1p31, which encodes a subunit of the receptor for the proinflammatory cytokine interleukin-23. An uncommon coding variant (rs11209026, c.1142G>A, p.Arg381Gln) confers strong protection against Crohn's disease, and additional noncoding IL23R variants are independently associated. Replication studies confirmed IL23R associations in independent cohorts of patients with Crohn's disease or ulcerative colitis. These results and previous studies on the proinflammatory role of IL-23 prioritize this signaling pathway as a therapeutic target in inflammatory bowel disease.

2,937 citations

Journal ArticleDOI
Jeffrey D. Stanaway1, Ashkan Afshin1, Emmanuela Gakidou1, Stephen S Lim1  +1050 moreInstitutions (346)
TL;DR: This study estimated levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs) by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or groups of risks from 1990 to 2017 and explored the relationship between development and risk exposure.

2,910 citations


Authors

Showing all 73373 results

NameH-indexPapersCitations
Karl J. Friston2171267217169
Yi Chen2174342293080
Yoshua Bengio2021033420313
Irving L. Weissman2011141172504
Mark I. McCarthy2001028187898
Lewis C. Cantley196748169037
Martin White1962038232387
Michael Marmot1931147170338
Michael A. Strauss1851688208506
Alan C. Evans183866134642
Douglas R. Green182661145944
David A. Weitz1781038114182
David L. Kaplan1771944146082
Hyun-Chul Kim1764076183227
Feng Zhang1721278181865
Network Information
Related Institutions (5)
University of Toronto
294.9K papers, 13.5M citations

98% related

University of Minnesota
257.9K papers, 11.9M citations

96% related

University of California, San Diego
204.5K papers, 12.3M citations

96% related

University of Washington
305.5K papers, 17.7M citations

96% related

Cornell University
235.5K papers, 12.2M citations

96% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023342
20221,000
20219,055
20208,668
20197,828
20187,237