Institution
McMaster University
Education•Hamilton, Ontario, Canada•
About: McMaster University is a education organization based out in Hamilton, Ontario, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 41361 authors who have published 101269 publications receiving 4251422 citations.
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McMaster University1, Université du Québec2, St. John's University3, University of the Philippines Manila4, Semmelweis University5, University of Cape Town6, Centra7, Uppsala University8, UCSI University9, Technion – Israel Institute of Technology10, University of Leicester11, Alfred Hospital12, Curtin University13, University of Quindío14, Cardiovascular Institute of the South15
TL;DR: Treatment with rosuvastatin at a dose of 10 mg per day resulted in a significantly lower risk of cardiovascular events than placebo in an intermediate-risk, ethnically diverse population without cardiovascular disease.
Abstract: BackgroundPrevious trials have shown that the use of statins to lower cholesterol reduces the risk of cardiovascular events among persons without cardiovascular disease. Those trials have involved persons with elevated lipid levels or inflammatory markers and involved mainly white persons. It is unclear whether the benefits of statins can be extended to an intermediate-risk, ethnically diverse population without cardiovascular disease. MethodsIn one comparison from a 2-by-2 factorial trial, we randomly assigned 12,705 participants in 21 countries who did not have cardiovascular disease and were at intermediate risk to receive rosuvastatin at a dose of 10 mg per day or placebo. The first coprimary outcome was the composite of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke, and the second coprimary outcome additionally included revascularization, heart failure, and resuscitated cardiac arrest. The median follow-up was 5.6 years. ResultsThe overall mean low-density lipop...
640 citations
TL;DR: In extremely-low-birth-weight infants, prophylaxis with indomethacin does not improve the rate of survival without neurosensory impairment at 18 months, despite the fact that it reduces the frequency of patent ductus arteriosus and severe periventricular and intraventricular hemorrhage.
Abstract: Background The prophylactic administration of indomethacin reduces the frequency of patent ductus arteriosus and severe intraventricular hemorrhage in very-low-birth-weight infants (those with birth weights below 1500 g). Whether prophylaxis with indomethacin confers any long-term benefits that outweigh the risks of drug-induced reductions in renal, intestinal, and cerebral blood flow is not known. Methods Soon after they were born, we randomly assigned 1202 infants with birth weights of 500 to 999 g (extremely low birth weight) to receive either indomethacin (0.1 mg per kilogram of body weight) or placebo intravenously once daily for three days. The primary outcome was a composite of death, cerebral palsy, cognitive delay, deafness, and blindness at a corrected age of 18 months. Secondary long-term outcomes were hydrocephalus necessitating the placement of a shunt, seizure disorder, and microcephaly within the same time frame. Secondary short-term outcomes were patent ductus arteriosus, pulmonary hemorrh...
640 citations
TL;DR: These studies provide the first evidence that pluripotential stem cells are present within adult skeletal muscle, including satellite cells, as well as new investigations into the embryonic origin of satellite cells.
640 citations
French Alternative Energies and Atomic Energy Commission1, Université catholique de Louvain2, Confederation College3, University of Liège4, University of Grenoble5, Université de Montréal6, Universidad de Bogotá Jorge Tadeo Lozano7, Rutgers University8, Chinese Academy of Sciences9, Central University of Finance and Economics10, Josip Juraj Strossmayer University of Osijek11, University of Coimbra12, University of the Basque Country13, University of West Virginia14, McMaster University15, Dalhousie University16
TL;DR: The present paper aims to describe the new capabilities of ABINIT that have been developed since 2009, which include new physical and technical features that allow electronic structure calculations impossible to carry out in the previous versions.
639 citations
TL;DR: In this article, a review of recent developments in the electrodeposition of ceramics and organoceramic materials is presented, which includes mass transport, accumulation of particles near the electrode and their coagulation to form a cathodic deposit, and interparticle forces that govern colloidal stability in the absence and presence of processing additives.
639 citations
Authors
Showing all 41721 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Salim Yusuf | 231 | 1439 | 252912 |
| Gordon H. Guyatt | 231 | 1620 | 228631 |
| Simon D. M. White | 189 | 795 | 231645 |
| George Efstathiou | 187 | 637 | 156228 |
| Stuart H. Orkin | 186 | 715 | 112182 |
| Terrie E. Moffitt | 182 | 594 | 150609 |
| John J.V. McMurray | 178 | 1389 | 184502 |
| Jasvinder A. Singh | 176 | 2382 | 223370 |
| Deborah J. Cook | 173 | 907 | 148928 |
| Andrew P. McMahon | 162 | 415 | 90650 |
| Jack Hirsh | 146 | 734 | 86332 |
| Holger J. Schünemann | 141 | 810 | 113169 |
| John A. Peacock | 140 | 565 | 125416 |
| David Price | 138 | 1687 | 93535 |
| Graeme J. Hankey | 137 | 844 | 143373 |