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Institution

McMaster University

EducationHamilton, Ontario, Canada
About: McMaster University is a education organization based out in Hamilton, Ontario, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 41361 authors who have published 101269 publications receiving 4251422 citations.


Papers
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Journal ArticleDOI
TL;DR: In this article, the authors provide support to the bedside clinician regarding the diagnosis, management and monitoring of circulatory shock, which is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate.
Abstract: Objective Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock.

1,142 citations

Journal ArticleDOI
24 Sep 2014-BMJ
TL;DR: It is shown that the quality of evidence supporting NMA estimates varies from high to very low across comparisons, and that quality ratings given to a whole network are uninformative and likely to mislead.
Abstract: Network meta-analysis (NMA), combining direct and indirect comparisons, is increasingly being used to examine the comparative effectiveness of medical interventions. Minimal guidance exists on how to rate the quality of evidence supporting treatment effect estimates obtained from NMA. We present a four-step approach to rate the quality of evidence in each of the direct, indirect, and NMA estimates based on methods developed by the GRADE working group. Using an example of a published NMA, we show that the quality of evidence supporting NMA estimates varies from high to very low across comparisons, and that quality ratings given to a whole network are uninformative and likely to mislead.

1,138 citations

Journal ArticleDOI
TL;DR: Findings are consistent with recent studies measuring CREB levels in this same subject sample, and support current animal and cellular models of antidepressant function.

1,138 citations

Journal ArticleDOI
TL;DR: A review of 31 empirical and eighteen substantive papers by qualitative social geographers mainly using in-depth interviews reveals little explicit reference to the principle(s) adopted to enhance "rigour" and to ensure meaningful inference as mentioned in this paper.
Abstract: A review of 31 empirical and eighteen substantive papers by qualitative social geographers mainly using in-depth interviews reveals little explicit reference to the principle(s) adopted to enhance ‘rigour’ and to ensure meaningful inference. Given the modest explicit discussion of evaluative criteria in these papers, a scheme from evaluation research itself is critically reviewed. A set of evaluation questions derived from this review and their application to an empirical piece of qualitative work frame an argument for a general set of criteria rather than rigid rules for assessing qualitative work. Such criteria can serve as anchor points for qualitative evaluation.

1,135 citations

Journal ArticleDOI
TL;DR: Fecal microbiota transplantation induces remission in a significantly greater percentage of patients with active UC than placebo, with no difference in adverse events.

1,135 citations


Authors

Showing all 41721 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Gordon H. Guyatt2311620228631
Simon D. M. White189795231645
George Efstathiou187637156228
Stuart H. Orkin186715112182
Terrie E. Moffitt182594150609
John J.V. McMurray1781389184502
Jasvinder A. Singh1762382223370
Deborah J. Cook173907148928
Andrew P. McMahon16241590650
Jack Hirsh14673486332
Holger J. Schünemann141810113169
John A. Peacock140565125416
David Price138168793535
Graeme J. Hankey137844143373
Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023168
2022521
20216,351
20205,747
20195,093
20184,604