Institution
Medical Research Council
Government•London, United Kingdom•
About: Medical Research Council is a government organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Malaria. The organization has 16430 authors who have published 19150 publications receiving 1475494 citations.
Papers published on a yearly basis
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TL;DR: Children aged 0-14 on a specified census day, with impairments of verbal and nonverbal communication, social interaction and imaginative play, and with repetitive, stereotyped activities, were identified in an epidemiological study carried out in an area of southeast London.
Abstract: Children aged 0-14 on a specified census day, with impairments of verbal and nonverbal communication, social interaction and imaginative play, and with repetitive, stereotyped activities, were identified in an epidemiological study carried out in an area of southeast London. Sociable moderately, severely, and profoundly retarded children were included for comparison. An overall male:female ratio of 2.6:1 was found in those with language and social impairments, but, in the children of this group who were moderately, severely, or profoundly retarded, the ratio was 2.1:1, closely similar to that found in children in the same IQ range with Down's syndrome or cerebral palsy. The excess of males was much more marked in language and socially impaired children who were of higher ability, or who had a history of typical early childhood autism. The findings were linked to hypotheses of genetically greater variability in males, and to male-female differences in visuo-spatial and language skills.
320 citations
TL;DR: DAT and ADE both achieve high remission rates and good long-term survival, and are equally effective chemotherapy regimens for the treatment of AML patients aged up to 55 years.
320 citations
TL;DR: In the rat, high levels of NGF mRNA were found in cerebral cortex, hippocampus and thalamus/hypothalamus, medium levels in striatum and brainstem, and low levels in cerebellum and spinal cord as discussed by the authors.
319 citations
TL;DR: It is found that compaction is regulated in two steps: Introduction of H4 acetylated to 30% on K16 inhibits compaction to a greater degree than deletion of the H4 N-terminal tail, and further decompaction is achieved by removal of the linker histone.
319 citations
TL;DR: The factors most strongly associated with poor survival were performance status and age at presentation, but even among those over 60 years of age, half went into remission, and those enrolled in the later half of the trial had a better survival.
319 citations
Authors
Showing all 16441 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Shizuo Akira | 261 | 1308 | 320561 |
| Trevor W. Robbins | 231 | 1137 | 164437 |
| Richard A. Flavell | 231 | 1328 | 205119 |
| George Davey Smith | 224 | 2540 | 248373 |
| Nicholas J. Wareham | 212 | 1657 | 204896 |
| Cyrus Cooper | 204 | 1869 | 206782 |
| Martin White | 196 | 2038 | 232387 |
| Frank E. Speizer | 193 | 636 | 135891 |
| Michael Rutter | 188 | 676 | 151592 |
| Richard Peto | 183 | 683 | 231434 |
| Terrie E. Moffitt | 182 | 594 | 150609 |
| Kay-Tee Khaw | 174 | 1389 | 138782 |
| Chris D. Frith | 173 | 524 | 130472 |
| Phillip A. Sharp | 172 | 614 | 117126 |
| Avshalom Caspi | 170 | 524 | 113583 |