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Institution

Memorial University of Newfoundland

EducationSt. John's, Newfoundland and Labrador, Canada
About: Memorial University of Newfoundland is a education organization based out in St. John's, Newfoundland and Labrador, Canada. It is known for research contribution in the topics: Population & Gadus. The organization has 13818 authors who have published 27785 publications receiving 743594 citations. The organization is also known as: Memorial University & Memorial University of Newfoundland and Labrador.


Papers
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Journal ArticleDOI
TL;DR: To examine the development of look duration as a function of age and stimulus type, 14- to 52-week-old infants were shown static and dynamic versions of faces, Sesame Street material, and achromatic patterns for 20 s of accumulated looking.
Abstract: To examine the development of look duration as a function of age and stimulus type, 14- to 52-week-old infants were shown static and dynamic versions of faces, Sesame Street material, and achromatic patterns for 20 s of accumulated looking Heart rate was recorded during looking and parsed into stimulus orienting, sustained attention, and attention termination phases Infants' peak look durations indicated that prior to 26 weeks there was a linear decrease with age for all stimuli Older infants' look durations continued to decline for patterns but increased for Sesame Street and faces Measures of heart rate change during sustained attention and the proportion of time spent in each phase of attention confirmed infants' greater engagement with the more complex stimuli

204 citations

Journal ArticleDOI
TL;DR: This study identifies chr1q32 and STAT3 as ankylosing spondylitis susceptibility loci and further confirms association for IL23R and detects suggestive association with another 4 loci, suggesting common aetiopathogenic pathways for AS and Crohn's disease.
Abstract: Ankylosing spondylitis (AS) is a common inflammatory arthritic condition. Overt inflammatory bowel disease (IBD) occurs in about 10% of AS patients, and in addition 70% of AS cases may have subclinical terminal ileitis. Spondyloarthritis is also common in IBD patients. We therefore tested Crohn's disease susceptibility genes for association with AS, aiming to identify pleiotropic genetic associations with both diseases. Genotyping was carried out using Sequenom and Applied Biosystems TaqMan and OpenArray technologies on 53 markers selected from 30 Crohn's disease associated genomic regions. We tested genotypes in a population of unrelated individual cases (n = 2,773) and controls (n = 2,215) of white European ancestry for association with AS. Statistical analysis was carried out using a Cochran-Armitage test for trend in PLINK. Strong association was detected at chr1q32 near KIF21B (rs11584383, P = 1.6×10−10, odds ratio (OR) = 0.74, 95% CI:0.68–0.82). Association with disease was also detected for 2 variants within STAT3 (rs6503695, P = 4.6×10−4. OR = 0.86 (95% CI:0.79–0.93); rs744166, P = 2.6×10−5, OR = 0.84 (95% CI:0.77–0.91)). Association was confirmed for IL23R (rs11465804, P = 1.2×10−5, OR = 0.65 (95% CI:0.54–0.79)), and further associations were detected for IL12B (rs10045431, P = 5.2×10−5, OR = 0.83 (95% CI:0.76–0.91)), CDKAL1 (rs6908425, P = 1.1×10−4, OR = 0.82 (95% CI:0.74–0.91)), LRRK2/MUC19 (rs11175593, P = 9.9×10−5, OR = 1.92 (95% CI: 1.38–2.67)), and chr13q14 (rs3764147, P = 5.9×10−4, OR = 1.19 (95% CI: 1.08–1.31)). Excluding cases with clinical IBD did not significantly affect these findings. This study identifies chr1q32 and STAT3 as ankylosing spondylitis susceptibility loci. It also further confirms association for IL23R and detects suggestive association with another 4 loci. STAT3 is a key signaling molecule within the Th17 lymphocyte differentiation pathway and further enhances the case for a major role of this T-lymphocyte subset in ankylosing spondylitis. Finally these findings suggest common aetiopathogenic pathways for AS and Crohn's disease and further highlight the involvement of common risk variants across multiple diseases.

204 citations

Journal ArticleDOI
TL;DR: This paper identified two categories of corporate responses grounded in different temporal perspectives: focused and integrated, and discussed the implications of this categorization for research on corporate environmentalism and time in organizational theory.
Abstract: Prior research often categorizes corporate environmental responses on a spectrum that ranges from reactive to proactive. Such research subordinates the role of time, yet time is central to organizational responses to environmental issues such as climate change. In this paper, we study five oil and gas firms and inductively develop a framework of corporate responses to climate change that explicitly acknowledges the role of time. The framework identifies two categories of corporate responses grounded in different temporal perspectives: focused and integrated. We discuss the implications of this categorization for research on corporate environmentalism and time in organizational theory.

203 citations

Journal ArticleDOI
TL;DR: In this paper, the physicochemical characteristics of the lintnerized residues at different time periods of hydrolysis were examined and the difference in the extent of the 8th day was influenced by the interplay between: (1) amount of lipid complexed amylose chains; (2) amylopectin content; (3) granule size; (4) pores on the granules surface.

203 citations

Journal ArticleDOI
TL;DR: In this article, the X-ray intensity of the V-amylose-lipid complex peak increased on annealing, whereas it remained unchanged in all other starches.

203 citations


Authors

Showing all 13990 results

NameH-indexPapersCitations
Daniel Levy212933194778
Rakesh K. Jain2001467177727
Peter W.F. Wilson181680139852
Martin G. Larson171620117708
Peter B. Jones145185794641
Dafna D. Gladman129103675273
Guoyao Wu12276456270
Fereidoon Shahidi11995157796
David Harvey11573894678
Robert C. Haddon11257752712
Se-Kwon Kim10276339344
John E. Dowling9430528116
Mark J. Sarnak9439342485
William T. Greenough9320029230
Soottawat Benjakul9289134336
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202386
2022269
20211,808
20201,749
20191,568
20181,516