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Institution

Michigan Technological University

EducationHoughton, Michigan, United States
About: Michigan Technological University is a education organization based out in Houghton, Michigan, United States. It is known for research contribution in the topics: Population & Volcano. The organization has 8023 authors who have published 17422 publications receiving 481780 citations. The organization is also known as: MTU & Michigan Tech.


Papers
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Journal ArticleDOI
TL;DR: In this paper, a low-cost, open source, self-replicating rapid prototyper (RepRap) has been developed, which greatly expands the potential user base of rapid prototypers.
Abstract: – A low‐cost, open source, self‐replicating rapid prototyper (RepRap) has been developed, which greatly expands the potential user base of rapid prototypers. The operating cost of the RepRap can be further reduced using waste polymers as feedstock. Centralized recycling of polymers is often uneconomic and energy intensive due to transportation embodied energy. The purpose of this paper is to provide a proof of concept for high‐value recycling of waste polymers at distributed creation sites., – Previous designs of waste plastic extruders (also known as RecycleBots) were evaluated using a weighted evaluation matrix. An updated design was completed and the description and analysis of the design is presented including component summary, testing procedures, a basic life cycle analysis and extrusion results. The filament was tested for consistency of density and diameter while quantifying electricity consumption., – Filament was successfully extruded at an average rate of 90 mm/min and used to print parts. The filament averaged 2.805 mm diameter with 87 per cent of samples between 2.540 mm and 3.081 mm. The average mass was 0.564 g/100 mm length. Energy use was 0.06 kWh/m., – The success of the RecycleBot further reduces RepRap operating costs, which enables distributed in‐home, value added, plastic recycling. This has implications for municipal waste management programs, as in‐home recycling could reduce cost and greenhouse gas emissions associated with waste collection and transportation, as well as the environmental impact of manufacturing custom plastic parts., – This paper reports on the first technical evaluation of a feedstock filament for the RepRap from waste plastic material made in a distributed recycling device.

223 citations

Journal ArticleDOI
17 Sep 2014-PLOS ONE
TL;DR: A new open-source method for developing and manufacturing high-quality scientific equipment suitable for use in virtually any laboratory and on the order of 5% or less than one would expect to pay for a commercial syringe pump having similar performance.
Abstract: This article explores a new open-source method for developing and manufacturing high-quality scientific equipment suitable for use in virtually any laboratory. A syringe pump was designed using freely available open-source computer aided design (CAD) software and manufactured using an open-source RepRap 3-D printer and readily available parts. The design, bill of materials and assembly instructions are globally available to anyone wishing to use them. Details are provided covering the use of the CAD software and the RepRap 3-D printer. The use of an open-source Rasberry Pi computer as a wireless control device is also illustrated. Performance of the syringe pump was assessed and the methods used for assessment are detailed. The cost of the entire system, including the controller and web-based control interface, is on the order of 5% or less than one would expect to pay for a commercial syringe pump having similar performance. The design should suit the needs of a given research activity requiring a syringe pump including carefully controlled dosing of reagents, pharmaceuticals, and delivery of viscous 3-D printer media among other applications.

222 citations

Journal ArticleDOI
TL;DR: It is shown that gibberellins in poplar repress lateral root formation through interactions with other hormones like auxin, which suggests a mechanism for GA-regulated modulation of lateral root proliferation associated with regulation of plant allometry during the stress response.
Abstract: The role of gibberellins (GAs) in regulation of lateral root development is poorly understood. We show that GA-deficient (35S:PcGA2ox1) and GA-insensitive (35S:rgl1) transgenic Populus exhibited increased lateral root proliferation and elongation under in vitro and greenhouse conditions, and these effects were reversed by exogenous GA treatment. In addition, RNA interference suppression of two poplar GA 2-oxidases predominantly expressed in roots also decreased lateral root formation. GAs negatively affected lateral root formation by inhibiting lateral root primordium initiation. A whole-genome microarray analysis of root development in GA-modified transgenic plants revealed 2069 genes with significantly altered expression. The expression of 1178 genes, including genes that promote cell proliferation, growth, and cell wall loosening, corresponded to the phenotypic severity of the root traits when transgenic events with differential phenotypic expression were compared. The array data and direct hormone measurements suggested crosstalk of GA signaling with other hormone pathways, including auxin and abscisic acid. Transgenic modification of a differentially expressed gene encoding an auxin efflux carrier suggests that GA modulation of lateral root development is at least partly imparted by polar auxin transport modification. These results suggest a mechanism for GA-regulated modulation of lateral root proliferation associated with regulation of plant allometry during the stress response.

220 citations

Journal ArticleDOI
TL;DR: In this paper, the optimal design of a micromotion stage with three piezoelectric actuators is presented, which consists of a monolithic flexure hinge mechanism with three actuators.
Abstract: Optimal design o1 a XYφ micromotion stage is presented. The stage consists of a monolithic flexure hinge mechanism with three piezoelectric actuators. This paper describes the procedures of selecting parameters for the optimal design. In particular, it presents a mathematical formulation of the optimization problem. Based on the solution of the optimiiation problem, the final design of the stage is also presented. Experimental results indicate that the design procedure is effective, and the designated stage has the total range of 41.5 μm mid 47.8 μm along the X- and Y-axes, respectively, and the maximum yaw motion range of 322.8 aresec (1.565 mrad).

219 citations

Journal ArticleDOI
15 Nov 1997-Genomics
TL;DR: The AAT tool reduces the labor-intensive work of locating the exons of the query sequence and improves the process of defining intron-exon boundaries by using the wealth of available protein and cDNA data.

218 citations


Authors

Showing all 8104 results

NameH-indexPapersCitations
Anil K. Jain1831016192151
Marc W. Kirschner162457102145
Yonggang Huang13679769290
Hong Wang110163351811
Fei Wang107182453587
Emanuele Bonamente10521940826
Haoshen Zhou10451937609
Nicholas J. Turro104113153827
Yang Shao-Horn10245849463
Richard P. Novick9929534542
Markus J. Buehler9560933054
Martin L. Yarmush9170234591
Alan Robock9034627022
Patrick M. Schlievert9044432037
Lonnie O. Ingram8831622217
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202349
2022154
2021882
2020891
2019892
2018893