Ministry of Supply

About: Ministry of Supply is a based out in . It is known for research contribution in the topics: Polarography & Bacillus (shape). The organization has 416 authors who have published 355 publications receiving 8951 citations. The organization is also known as: MoS.

Pseudo-cholinesterase in Rat Erythrocytes

Abstract: ALTHOUGH there are many references in the literature to the existence of different types of cholinesterase in mammalian sera1, it is generally believed that human red cells contain only one type2. Furthermore, we can find no evidence in the literature for the existence of a pseudo-cholinesterase in any mammalian erythrocytes, although many workers have stated that benzoylcholine is hydrolysed by red cells. Since, however, the rate of hydrolysis is slow, this breakdown of a substrate formerly presumed to be specific for pseudo-cholinesterase has been attributed to true cholinesterase. Indeed, Adams3 has shown that purified true cholinesterase does hydrolyse benzoylcholine, at a rate which would account for such observations. In spite of this, some results obtained by Fraser with benzoylcholine4 imply the existence of more than one type of cholinesterase in red cells.

Solubility as a criterion of purity

Abstract: A method for the determination of the purity of a compound by means of a series of solubility determinations (described in the case of one impurity by Northrop and Kunitz1) has been shown to give 1 The number of main impurities present; 2 the percentage of each impurity; 3 the solubility of the compound; 4 the solubilities of the impurities. The method which may prove very useful, especially in cases where the probable impurities are related com pounds, e.g., other members of a homologous series, has been applied with success to DDT (Dichloro-diphenyl-trichloroethane) and to 22′, 44′ 66′ NN′ oetachloro-diphenyl-urea.

The correlation of explosive power with molecular structure

Abstract: The relationship of oxygen balance to explosive power as measured by the ballistic mortar has been studied empirically. Starting from the modified oxygen balance developed by the authors for detonation velocity calculations, a numerical measure called the ‘power index’ has been derived which correlates closely the features of molecular structure with the power values. Explosive power has also been expressed as an additive function of details of molecular structure. This has been made the basis of a method whereby power values may he derived which agree with experimental results to about 5% and which provides a rapid alternative to the thermochemical calculations which result from normal theoretical treatment.