Mississippi State University

About: Mississippi State University is a education organization based out in Starkville, Mississippi, United States. It is known for research contribution in the topics: Population & Catfish. The organization has 14115 authors who have published 28594 publications receiving 700030 citations. The organization is also known as: The Mississippi State University of Agriculture and Applied Science & Mississippi State University of Agriculture and Applied Science.

DNA Damage-Induced Replication Fork Regression and Processing in Escherichia coli

Abstract: DNA lesions that block replication are a primary cause of rearrangements, mutations, and lethality in all cells. After ultraviolet (UV)-induced DNA damage in Escherichia coli, replication recovery requires RecA and several other recF pathway proteins. To characterize the mechanism by which lesion-blocked replication forks recover, we used two-dimensional agarose gel electrophoresis to show that replication-blocking DNA lesions induce a transient reversal of the replication fork in vivo. The reversed replication fork intermediate is stabilized by RecA and RecF and is degraded by the RecQ-RecJ helicase-nuclease when these proteins are absent. We propose that fork regression allows repair enzymes to gain access to the replication-blocking lesion, allowing processive replication to resume once the blocking lesion is removed.

Performance analysis of CCHP and CHP systems operating following the thermal and electric load

Abstract: Heating and cooling energy requirements for buildings are usually supplied by separated systems such as furnaces or boilers for heating, and vapor compression systems for cooling. For these types of buildings, the use of combined cooling, heating, and power (CCHP) systems or combined heating and power (CHP) systems are an alternative for energy savings. Different researchers have claimed that the use of CCHP and CHP systems reduces the energy consumption related to transmission and distribution of energy. However, most of these analyses are based on reduction of operating cost without measuring the actual energy use and emissions reduction. The objective of this study is to analyze the performance of CCHP and CHP systems operating following the electric load (FEL) and operating following the thermal load (FTL), based on primary energy consumption (PEC), operation cost, and carbon dioxide emissions (CDE) for different climate conditions. Results show that CCHP and CHP systems operated FTL reduce the PEC for all the evaluated cities. On the other hand, CHP systems operated FEL always increases the PEC. The only operation mode that reduces PEC and CDE while reducing the cost is CHP-FTL. Copyright © 2009 John Wiley & Sons, Ltd.