Mitsubishi

About: Mitsubishi is a company organization based out in Tokyo, Japan. It is known for research contribution in the topics: Layer (electronics) & Signal. The organization has 53115 authors who have published 54821 publications receiving 870150 citations. The organization is also known as: Mitsubishi Group of Companies & Mitsubishi Companies.

Hybrid integrated circuit device

Abstract: A hybrid integrated circuit device includes a circuit board having at least two electrical conductors; a chip resistor bridgingly disposed across two of the electrical conductors of the circuit board; and solder electrically connecting the chip resistor to the two electrical conductors. The chip resistor has an electrically insulating substrate, two electrodes disposed on the electrically insulating substrate, separated from each other, and each electrode has a contact end electrically contacting the electrical conductors of the circuit board and a resistor element disposed on the electrically insulating substrate and electrically connected to the contact ends of the electrodes. The solder electrically connects the electrodes of the chip resistor to the electrical conductors of the circuit board.

Artificial intelligence software shell for plant operation simulation

Abstract: An artificial intelligence software shell for plant operation simulation includes a blackboard module including a database having objects representing plant elements and concepts A rule-based knowledge source module and a case-based knowledge source module, in communication with the blackboard module, operate on specific predefined blackboard objects A user interface module, in communication with the blackboard module, enables a user to view blackboard status information A control module, in communication with the blackboard module and the knowledge source modules, receives input data and controls operation of the knowledge source modules in accordance with a predetermined knowledge source priority scheme

Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities.

Abstract: Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities

Driving environment surveillance apparatus

Abstract: A driving environment surveillance apparatus is provided to specify a region where an obstacle is present depending upon an azimuth detected by an obstacle detecting unit so as to derive a two-dimensional image corresponding to the specified region from an image detecting unit, and to extract the obstacle from the two-dimensional image so as to calculate a size index of the obstacle, thereby detecting a relative distance or the azimuth to the obstacle from a vehicle with high accuracy and at a high speed.

Actin depolymerizing factor and cofilin phosphorylation dynamics: Response to signals that regulate neurite extension

Abstract: The actin assembly-regulating activity of actin depolymerizing factor (ADF)/cofilin is inhibited by phosphorylation. Studies were undertaken to characterize the signaling pathways and phosphatases involved in activating phosphorylated ADF (pADF), emphasizing signals related to neuronal process extension. Western blots using antibodies to ADF and cofilin, as well as an ADF/cofilin phosphoepitope-specific antibody characterized in this paper, were used to measure changes in the phosphorylation state and phosphate turnover of ADF/cofilin in response to inhibitors and agents known to influence growth cone motility. Increases in both [Ca2+]i and cAMP levels induced rapid pADF dephosphorylation in HT4 and cortical neurons. Calcium-dependent dephosphorylation depended on the activation of protein phosphatase 2B (PP2B), while cAMP-dependent dephosphorylation was likely through activation of PP1. Growth factors such as NGF and insulin also induced rapid pADF/pcofilin dephosphorylation, with NGF-stimulated dephosphorylation in PC12 cells correlated with the translocation of ADF/cofilin to ruffling membranes. Of special interest was the finding that the rate of phosphate turnover on both pADF and pcofilin could be enhanced by growth factors without changing net pADF levels, demonstrating that growth factors can activate bifurcating pathways that promote both phosphorylation and dephosphorylation of ADF/cofilin. All experimental results indicated that dynamics of phosphorylation on ADF and cofilin are coordinately regulated. Signals that decreased pADF levels are associated with increased process extension, while agents that increased pADF levels, such as lysophosphatidic acid, inhibit process extension. These data indicate that dephosphorylation/activation of pADF is a significant response to the activation of signal pathways that regulate actin dynamics and alter cell morphology and neuronal outgrowth. Cell Motil. Cytoskeleton 39:172–190, 1998. © 1998 Wiley-Liss, Inc.