Moscow Institute of Physics and Technology

About: Moscow Institute of Physics and Technology is a education organization based out in Dolgoprudnyy, Russia. It is known for research contribution in the topics: Laser & Large Hadron Collider. The organization has 8594 authors who have published 16968 publications receiving 246551 citations. The organization is also known as: MIPT & Moscow Institute of Physics and Technology (State University).

Generation of collimated beams of relativistic ions in laser-plasma interactions

Abstract: A method is proposed for generating collimated beams of fast ions in laser-plasma interactions. Two-dimensional and three-dimensional particle-in-cell simulations show that the ponderomotive force expels electrons from the plasma region irradiated by a laser pulse. The ions with unneutralized electric charge that remain in this region are accelerated by Coulomb repulsive forces. The ions are focused by tailoring the target and also as a result of pinching in the magnetic field produced by the electric current of fast ions.

A transition from parabolic to conical shape as a common effect in nearby AGN jets

Abstract: Observational studies of collimation in jets in active galactic nuclei (AGN) are a key to understanding their formation and acceleration processes. We have performed an automated search for jet shape transitions in a sample of 367 AGN using VLBA data at 15 GHz and 1.4 GHz. This search has found ten out of 29 nearby jets at redshifts z<0.07 with a transition from a parabolic to conical shape, while the full analyzed sample is dominated by distant AGN with a typical z about 1. The ten AGN are UGC00773, NGC1052, 3C111, 3C120, TXS0815-094, Mrk180, PKS1514+00, NGC6251, 3C371, and BL Lac. We conclude that the geometry transition may be a common effect in AGN jets. It can be observed only when sufficient linear resolution is obtained. Supplementing these results with previously reported shape breaks in the nearby AGN 1H0323+342 and M87, we estimate that the break occurs at 10^5-10^6 gravitational radii from the nucleus. We suggest that the jet shape transition happens when the bulk plasma kinetic energy flux becomes equal to the Poynting energy flux, while the ambient medium pressure is assumed to be governed by Bondi accretion. In general, the break point may not coincide with the Bondi radius. The observational data supports our model predictions on the jet acceleration and properties of the break point.

Outer membrane vesicles secreted by pathogenic and nonpathogenic Bacteroides fragilis represent different metabolic activities.

Abstract: Numerous studies are devoted to the intestinal microbiota and intercellular communication maintaining homeostasis. In this regard, vesicles secreted by bacteria represent one of the most popular topics for research. For example, the outer membrane vesicles (OMVs) of Bacteroides fragilis play an important nutritional role with respect to other microorganisms and promote anti-inflammatory effects on immune cells. However, toxigenic B. fragilis (ETBF) contributes to bowel disease, even causing colon cancer. If nontoxigenic B. fragilis (NTBF) vesicles exert a beneficial effect on the intestine, it is likely that ETBF vesicles can be utilized for potential pathogenic implementation. To confirm this possibility, we performed comparative proteomic HPLC-MS/MS analysis of vesicles isolated from ETBF and NTBF. Furthermore, we performed, for the first time, HPLC-MS/MS and GS-MS comparative metabolomic analysis for the vesicles isolated from both strains with subsequent reconstruction of the vesicle metabolic pathways. We utilized fluxomic experiments to validate the reconstructed biochemical reaction activities and finally observed considerable difference in the vesicle proteome and metabolome profiles. Compared with NTBF OMVs, metabolic activity of ETBF OMVs provides their similarity to micro reactors that are likely to be used for long-term persistence and implementing pathogenic potential in the host.