Institution
Moscow State University
Education•Moscow, Russia•
About: Moscow State University is a education organization based out in Moscow, Russia. It is known for research contribution in the topics: Laser & Population. The organization has 66747 authors who have published 123358 publications receiving 1753995 citations. The organization is also known as: MSU & Lomonosov Moscow State University.
Topics: Laser, Population, Catalysis, Magnetic field, Magnetization
Papers published on a yearly basis
Papers
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361 citations
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TL;DR: The impact of mitochondria on cancer is summarized, the possibilities to target mitochondria for anticancer therapies are given, and mitochondria‐targeted antioxidants are found to be effective in cancer prevention and anticancer therapy.
Abstract: Mitochondria are indispensable for energy metabolism, apoptosis regulation, and cell signaling. Mitochondria in malignant cells differ structurally and functionally from those in normal cells and participate actively in metabolic reprogramming. Mitochondria in cancer cells are characterized by reactive oxygen species (ROS) overproduction, which promotes cancer development by inducing genomic instability, modifying gene expression, and participating in signaling pathways. Mitochondrial and nuclear DNA mutations caused by oxidative damage that impair the oxidative phosphorylation process will result in further mitochondrial ROS production, completing the "vicious cycle" between mitochondria, ROS, genomic instability, and cancer development. The multiple essential roles of mitochondria have been utilized for designing novel mitochondria-targeted anticancer agents. Selective drug delivery to mitochondria helps to increase specificity and reduce toxicity of these agents. In order to reduce mitochondrial ROS production, mitochondria-targeted antioxidants can specifically accumulate in mitochondria by affiliating to a lipophilic penetrating cation and prevent mitochondria from oxidative damage. In consistence with the oncogenic role of ROS, mitochondria-targeted antioxidants are found to be effective in cancer prevention and anticancer therapy. A better understanding of the role played by mitochondria in cancer development will help to reveal more therapeutic targets, and will help to increase the activity and selectivity of mitochondria-targeted anticancer drugs. In this review we summarized the impact of mitochondria on cancer and gave summary about the possibilities to target mitochondria for anticancer therapies. J. Cell. Physiol. 231: 2570-2581, 2016. © 2016 Wiley Periodicals, Inc.
361 citations
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TL;DR: This tutorial defines and discusses key aspects of the problem of computational inference of aesthetics and emotion from images and describes data sets available for performing assessment and outline several real-world applications where research in this domain can be employed.
Abstract: In this tutorial, we define and discuss key aspects of the problem of computational inference of aesthetics and emotion from images. We begin with a background discussion on philosophy, photography, paintings, visual arts, and psychology. This is followed by introduction of a set of key computational problems that the research community has been striving to solve and the computational framework required for solving them. We also describe data sets available for performing assessment and outline several real-world applications where research in this domain can be employed. A significant number of papers that have attempted to solve problems in aesthetics and emotion inference are surveyed in this tutorial. We also discuss future directions that researchers can pursue and make a strong case for seriously attempting to solve problems in this research domain.
361 citations
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TL;DR: Based on the results inferred from molecular data and morphological and physiochemical features, an updated classification for the Tremellomycetes is proposed and five orders, 17 families and 54 genera are accepted, including seven new families and 18 new genera.
361 citations
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TL;DR: In this article, the authors presented the electron and photon energy calibration achieved with the ATLAS detector using about 25 fb(-1) of LHC proton-proton collision data taken at center-of-mass energies of root s = 7 and 8 TeV.
Abstract: This paper presents the electron and photon energy calibration achieved with the ATLAS detector using about 25 fb(-1) of LHC proton-proton collision data taken at centre-of-mass energies of root s = 7 and 8 TeV. The reconstruction of electron and photon energies is optimised using multivariate algorithms. The response of the calorimeter layers is equalised in data and simulation, and the longitudinal profile of the electromagnetic showers is exploited to estimate the passive material in front of the calorimeter and reoptimise the detector simulation. After all corrections, the Z resonance is used to set the absolute energy scale. For electrons from Z decays, the achieved calibration is typically accurate to 0.05% in most of the detector acceptance, rising to 0.2% in regions with large amounts of passive material. The remaining inaccuracy is less than 0.2-1% for electrons with a transverse energy of 10 GeV, and is on average 0.3% for photons. The detector resolution is determined with a relative inaccuracy of less than 10% for electrons and photons up to 60 GeV transverse energy, rising to 40% for transverse energies above 500 GeV.
361 citations
Authors
Showing all 68238 results
Name | H-index | Papers | Citations |
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Krzysztof Matyjaszewski | 169 | 1431 | 128585 |
A. Gomes | 150 | 1862 | 113951 |
Robert J. Sternberg | 149 | 1066 | 89193 |
James M. Tour | 143 | 859 | 91364 |
Alexander Belyaev | 142 | 1895 | 100796 |
Rainer Wallny | 141 | 1661 | 105387 |
I. V. Gorelov | 139 | 1916 | 103133 |
António Amorim | 136 | 1477 | 96519 |
Halina Abramowicz | 134 | 1192 | 89294 |
Grigory Safronov | 133 | 1358 | 94610 |
Elizaveta Shabalina | 133 | 1421 | 92273 |
Alexander Zhokin | 132 | 1323 | 86842 |
Eric Conte | 132 | 1206 | 84593 |
Igor V. Moskalenko | 132 | 542 | 58182 |
M. Davier | 132 | 1449 | 107642 |