Institution
Motilal Nehru National Institute of Technology Allahabad
Education•Allahabad, Uttar Pradesh, India•
About: Motilal Nehru National Institute of Technology Allahabad is a education organization based out in Allahabad, Uttar Pradesh, India. It is known for research contribution in the topics: Control theory & Electric power system. The organization has 2475 authors who have published 5067 publications receiving 61891 citations. The organization is also known as: NIT Allahabad & Motilal Nehru Regional Engineering College.
Papers published on a yearly basis
Papers
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TL;DR: An algorithm to automatically detect the cataracts from color images in adult human subjects based on texture features: uniformity, intensity and standard deviation is proposed and a tele-ophthamology model using this system has been suggested, which confirms the telemedicine application of the proposed system.
Abstract: This paper proposes and evaluates an algorithm to automatically detect the cataracts from color images in adult human subjects. Currently, methods available for cataract detection are based on the use of either fundus camera or Digital Single-Lens Reflex (DSLR) camera; both are very expensive. The main motive behind this work is to develop an inexpensive, robust and convenient algorithm which in conjugation with suitable devices will be able to diagnose the presence of cataract from the true color images of an eye. An algorithm is proposed for cataract screening based on texture features: uniformity, intensity and standard deviation. These features are first computed and mapped with diagnostic opinion by the eye expert to define the basic threshold of screening system and later tested on real subjects in an eye clinic. Finally, a tele-ophthamology model using our proposed system has been suggested, which confirms the telemedicine application of the proposed system.
27 citations
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TL;DR: The findings reveal the potential of this biomarker panel as a suitable diagnostic serum biomarker for early screening of OC and confirms the elevated performance of novel epigenetic marker panel (HOXA9 and HIC1) when analyzed in tissue and matched serum samples.
Abstract: Accumulated evidence revealed that aberrant CpG island hypermethylation plays an important role in carcinogenesis which can serve as a promising target for molecular detection in body fluids. Despite a myriad of attempts to diagnose ovarian cancer (OC) at an early stage, this clinical aim remains a major challenge. To date, no single biomarker is able to accurately detect early OC in either tissue or body fluid. Aberrant DNA methylation patterns in circulating DNA provide highly specific cancer signals. In our study, we establish a novel panel of methylation-specific genes for the development of a TaqMan based qPCR assay to quantify methylation levels. We analyzed promoter methylation of homeobox A9 (HOXA9) and hypermethylated in cancer 1 (HIC1) quantitatively in 120 tissue samples and in 70 matched serum cell-free DNA (CFDNA) of cancerous and noncancerous samples by MethyLight assay. HOXA9 and HIC1 methylation occurred in 82.3 and 80.0% of OC tissue samples in singleplex assay, thereby confirming that methylation was highly cancer-specific. When either or both gene promoter showed methylation, the sensitivity was 88.2% with a specificity of 88.6% in tissue samples. The combined sensitivity for this novel marker panel in serum CFDNA was 88.9% (area under the curve [AUC] = 0.95). In contrast, no hypermethylation was observed in serum from matched cancer-free control women. Our results confirm the elevated performance of novel epigenetic marker panel (HOXA9 and HIC1) when analyzed in tissue and matched serum samples. Our findings reveal the potential of this biomarker panel as a suitable diagnostic serum biomarker for early screening of OC.
27 citations
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TL;DR: In this paper, a detailed comparison of a few numerical models (with and without considering humid air properties) for the estimation of water production from a solar water distillation device is investigated.
27 citations
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27 citations
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TL;DR: A fault tolerant controller has been designed for three-pole magnetic bearings to provide unaltered performance in the event of fault occurrence and is found to be robust as it provides satisfactory operation in the presence of uncertainties.
Abstract: Active magnetic bearings have many advantages over conventional bearings due to contactless operation and adjustable force dynamics. However, one of the obstacles associated with these bearings is failure modes, which may result in destructive rotor dynamic behaviour. One of the important failure modes is electric power outage which may be due to failure of power amplifier, coil or electric wiring. In the present work, a fault tolerant controller has been designed for three-pole magnetic bearings to provide unaltered performance in the event of fault occurrence. The controller has been designed by incorporating the nonlinear fuzzy logic control. The present design of fuzzy logic controller is done by reducing the number of rules of its rule base. Simulations have been carried out to test the performance of the controller for different failure conditions. The designed controller is able to stabilize the rotor for large deviations from the origin even in the presence of failure. The controller is found to be robust as it provides satisfactory operation in the presence of uncertainties.
27 citations
Authors
Showing all 2547 results
Name | H-index | Papers | Citations |
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Santosh Kumar | 80 | 1196 | 29391 |
Anoop Misra | 70 | 385 | 17301 |
Naresh Kumar | 66 | 1106 | 20786 |
Munindar P. Singh | 62 | 580 | 20279 |
Arvind Agarwal | 58 | 325 | 12365 |
Mahendra Kumar | 54 | 216 | 9170 |
Jay Singh | 51 | 301 | 8655 |
Lalit Kumar | 47 | 381 | 11014 |
O.N. Srivastava | 47 | 548 | 10308 |
Avinash C. Pandey | 45 | 301 | 7576 |
Sunil Gupta | 43 | 518 | 8827 |
Rakesh Mishra | 41 | 545 | 7385 |
Durgesh Kumar Tripathi | 37 | 133 | 5937 |
Vandana Singh | 35 | 190 | 4347 |
Prashant K. Sharma | 34 | 174 | 3662 |