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Showing papers by "Mulago Hospital published in 1968"


Journal ArticleDOI
TL;DR: In this paper, it was shown that stimulation of the peripheral part of the presacral nerve supply to the rectal and anal region produces relaxation of the internal anal sphincter.
Abstract: 1. In man under nitrous oxide/oxygen anesthesia, stimulation of the peripheral part of the presacral nerve supply to the rectal and anal region produces relaxation of the internal anal sphincter.

40 citations


Journal ArticleDOI
TL;DR: It is thought probable that children who have had Kwashiorkor, even if adequately treated, have a higher incidence of pancreatic disease than those who have not, and protein malnutrition may be of importance in the etiology of chronic pancreatic Disease in Uganda.
Abstract: Carbohydrate tolerance tests have been performed on 52 African children in Uganda. Thirty-one of the children had been treated for Kwashiorkor 5.2 to 12.2 (mean 8.5) years before, and 21 had no history of severe malnutrition in the past. Intravenous-glucose tolerance (K) was significantly impaired in the children who had had Kwashiorkor. There was a tendency for the tolerance to improve after admission to hospital which was unexpected for the home-diets were all presumed to be rich in carbohydrate; this change was not statistically significant. There was a significant inverse correlation between the individual intravenous-glucose tolerance K values and the blood-glucose rise at 2 1 2 hours after its oral administration. The mean rise at 2 1 2 hours was significantly greater in the children who had had Kwashiorkor than in those who had not. Blood-glucose curves after oral-starch were more often relatively flat in the children who had had Kwashiorkor than the controls. A significant correlation was found between the individual K values and ratios of maximum rise in blood-glucose after oral-starch to that after oral-glucose ( S G ). The interpretation of these results is discussed; it is thought probable that children who have had Kwashiorkor, even if adequately treated, have a higher incidence of pancreatic disease than those who have not. Protein malnutrition may be of importance in the etiology of chronic pancreatic disease in Uganda.

20 citations


Journal ArticleDOI
TL;DR: African subjects in Uganda with isolated lactase deficiency have a significant lactosuria after an oral lactose load, which can be detected by the Clinitest method, and probably has a value in screening African populations for lact enzyme deficiency.
Abstract: African subjects in Uganda with isolated lactase deficiency have a significant lactosuria after an oral lactose load. This can be detected by the Clinitest method, and probably has a value in screening African populations for lactase deficiency.

12 citations