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Institution

Mulago Hospital

HealthcareKampala, Uganda
About: Mulago Hospital is a healthcare organization based out in Kampala, Uganda. It is known for research contribution in the topics: Population & Health care. The organization has 542 authors who have published 545 publications receiving 34804 citations.


Papers
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Journal ArticleDOI
TL;DR: The evolution and current status of pediatric cardiovascular care in Uganda is described, highlighting the unique aspects of its establishment, existing constraints, and future plans.
Abstract: In many developing countries, concerted action against common childhood infectious diseases has resulted in remarkable reduction in infant and under-five mortality. As a result, pediatric cardiovascular diseases are emerging as a major contributor to childhood morbidity and mortality. Pediatric cardiac surgery and cardiac catheterization interventions are available in only a few of Sub-Saharan African countries. In Uganda, open heart surgeries (OHSs) and interventional procedures for pediatric cardiovascular disease are only possible at the Uganda Heart Institute (UHI), having been started with the help of expatriate teams from the years 2007 and 2012, respectively. Thereafter, independent OHS and cardiac catheterization have been possible by the local team at the UHI since the year 2009 and 2013, respectively. The number of OHSs independently performed by the UHI team has progressively increased from 10 in 2010 to 35 in 2015, with mortality rates ranging from 0% to 4.1% over the years. The UHI pediatric catheterization team has independently performed an increasing number of procedures each year from 3 in 2013 to 55 in 2015. We herein describe the evolution and current status of pediatric cardiovascular care in Uganda, highlighting the unique aspects of its establishment, existing constraints, and future plans.

27 citations

Journal ArticleDOI
12 Feb 2016-PLOS ONE
TL;DR: Overall acceptability was found to be equivalent between the two study groups and treatment of incomplete abortion with misoprostol by midwives and physician was highly, and equally, acceptable to women.
Abstract: OBJECTIVE: This study aimed to assess women´s acceptability of diagnosis and treatment of incomplete abortion with misoprostol by midwives, compared with physicians.METHODS: This was an analysis of ...

27 citations

Journal ArticleDOI
TL;DR: The level of consciousness, hemoglobin concentration, blood lactate level, and thigh muscle tSo2 level were poor predictors of cerebral oxygen saturation, and more studies are needed to evaluate the use of noninvasive cerebral tissue oximetry in the care of children with severe anemia.
Abstract: Importance Severe anemia, defined as a hemoglobin level of less than 5.0 g/dL, affects millions of children worldwide. The brain has a high basal demand for oxygen and is especially vulnerable to hypoxemia. Previous studies have documented neurocognitive impairment in children with severe anemia. Data on cerebral tissue oxygenation in children with severe anemia and their response to blood transfusion are limited. Objective To measure hemoglobin saturation in cerebral tissue (cerebral tissue oxygen saturation [tSo 2 ]) before, during, and after blood transfusion in a cohort of children presenting to hospital with severe anemia. Design, Setting, and Participants This was a prospective, observational cohort study conducted from February 2013 through May 2015 and analyzed in July 2015 at a university hospital pediatric acute care facility in Kampala, Uganda, of 128 children, ages 6 to 60 months who were enrolled in a larger clinical trial, with a presenting hemoglobin level of less than 5.0 g/dL and a blood lactate level greater than 5mM. Most children had either malaria or sickle cell disease. Exposures Red blood cell (RBC) transfusion given as 10 mL/kg over 120 minutes. Main Outcomes and Measures Clinical and laboratory characteristics of children with pretransfusion cerebral tSo 2 levels less than 65%, 65% to 75%, and greater than 75%. Change in cerebral tSo 2 as a result of transfusion. Results Of 128 children included in the study, oximetry results in 8 cases were excluded owing to motion artifacts; thus, 120 were included in this analysis. Cerebral tSo 2 values prior to transfusion ranged from 34% to 87% (median, 72%; interquartile range [IQR], 65%-76%). Eighty-one children (67%) demonstrated an initial cerebral tSo 2 level (≤75%) corresponding to an oxygen extraction ratio greater than 0.36. Patients with sickle cell disease (n = 17) and malaria (n = 15) contributed in nearly equal numbers to the subgroup with an initial cerebral tSo 2 ( 2 level were poor predictors of cerebral oxygen saturation. Following RBC transfusion, the median (IQR) cerebral tSo 2 level increased to 78% (73%-82%) ( P 2 level greater than 75%. Conclusions and Relevance Severe anemia in children is frequently associated with low cerebral oxygenation levels as measured by near-infrared spectroscopy. Hemoglobin level and lactate concentration did not predict low cerebral tSo 2 levels. Cerebral tSo 2 levels increase with RBC transfusion with different patterns of response. More studies are needed to evaluate the use of noninvasive cerebral tissue oximetry in the care of children with severe anemia.

26 citations

Journal ArticleDOI
TL;DR: The prevalence and clinical course of pulmonary cryptococcosis in Sub-Saharan Africa are not well-described as discussed by the authors, however, the authors of this paper are aware of only three cases.
Abstract: Background The prevalence and clinical course of pulmonary cryptococcosis in Sub-Saharan Africa are not well-described.

26 citations

Journal ArticleDOI
27 Dec 2019
TL;DR: Higher sexual activity & pregnancy stigma and modern family planning & abortion stigma were associated with reduced odds of HIV testing services awareness, andmodern family planning and abortion stigma was associated with reduction of lifetime HIV testing odds.
Abstract: © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http:// creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

26 citations


Authors

Showing all 545 results

NameH-indexPapersCitations
Moses R. Kamya6043512598
Jordan J. Feld5727713444
Eloi Marijon4735210005
Sarah G. Staedke471696095
Harriet Mayanja-Kizza432216804
Alphonse Okwera42885187
Joo-Hyun Nam412317216
James K Tumwine412145413
Ian Crozier401427922
Cissy Kityo391965926
Philippa Musoke371387778
Andrew Kambugu361845195
Denis Burkitt35738491
Richard Idro351394312
Robert O. Opoka331704927
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20223
202131
202027
201929
201822
201729