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Institution

Murdoch University

EducationPerth, Western Australia, Australia
About: Murdoch University is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Genome. The organization has 5921 authors who have published 18190 publications receiving 492237 citations.


Papers
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Journal ArticleDOI
TL;DR: The largest declines in risk exposure from 2010 to 2019 were among a set of risks that are strongly linked to social and economic development, including household air pollution; unsafe water, sanitation, and handwashing; and child growth failure.

3,059 citations

Journal ArticleDOI
Rudi Appels1, Rudi Appels2, Kellye Eversole, Nils Stein3  +204 moreInstitutions (45)
17 Aug 2018-Science
TL;DR: This annotated reference sequence of wheat is a resource that can now drive disruptive innovation in wheat improvement, as this community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
Abstract: An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.

2,118 citations

Journal ArticleDOI
TL;DR: A computer program, ARAGORN, identifies tRNA and tmRNA genes using heuristic algorithms to predict tRNA secondary structure, based on homology with recognized tRNA consensus sequences and ability to form a base-paired cloverleaf.
Abstract: A computer program, ARAGORN, identifies tRNA and tmRNA genes. The program employs heuristic algorithms to predict tRNA secondary structure, based on homology with recognized tRNA consensus sequences and ability to form a base-paired cloverleaf. tmRNA genes are identified using a modified version of the BRUCE program. ARAGORN achieves a detection sensitivity of 99% from a set of 1290 eubacterial, eukaryotic and archaeal tRNA genes and detects all complete tmRNA sequences in the tmRNA database, improving on the performance of the BRUCE program. Recently discovered tmRNA genes in the chloroplasts of two species from the 'green' algae lineage are detected. The output of the program reports the proposed tRNA secondary structure and, for tmRNA genes, the secondary structure of the tRNA domain, the tmRNA gene sequence, the tag peptide and a list of organisms with matching tmRNA peptide tags.

1,964 citations

Journal ArticleDOI
TL;DR: The minimal standards for the quality of genome sequences and how they can be applied for taxonomic purposes are described.
Abstract: Advancement of DNA sequencing technology allows the routine use of genome sequences in the various fields of microbiology. The information held in genome sequences proved to provide objective and reliable means in the taxonomy of prokaryotes. Here, we describe the minimal standards for the quality of genome sequences and how they can be applied for taxonomic purposes.

1,908 citations

Journal ArticleDOI
TL;DR: The issues relevant to those types of ecosystems containing new combinations of species that arise through human action, environmental change, and the impacts of the deliberate and inadvertent introduction of species from other regions are explored.
Abstract: We e xplore the issues relevant to those types of ecosystems containing new combinations of species that arise through human action, environmental change, and the impacts of the deliberate and inadvertent introduction of species from other regions. Novel ecosystems (also termed ‘emerging ecosystems’) result when species occur in combinations and relative abundances that have not occurred previously within a given biome. Key characteristics are novelty, in the form of new species combinations and the potential for changes in ecosystem functioning, and human agency, in that these ecosystems are the result of deliberate or inadvertent human action. As more of the Earth becomes transformed by human actions, novel ecosystems increase in importance, but are relatively little studied. Either the degradation or invasion of native or ‘wild’ ecosystems or the abandonment of intensively managed systems can result in the formation of these novel systems. Important considerations are whether these new systems are persistent and what values they may have. It is likely that it may be very difficult or costly to return such systems to their previous state, and hence consideration needs to be given to developing appropriate management goals and approaches.

1,793 citations


Authors

Showing all 6008 results

NameH-indexPapersCitations
Jeremy K. Nicholson14177380275
John J. McGrath120791124804
Elaine Holmes11956058975
Mike S. M. Jetten11748852356
Richard J. Hobbs10859268141
Rajeev K. Varshney10270939796
Henry Brodaty10184448276
Michael W. Anderson10180863603
John C. Lindon9948844063
Kim L Bennell9962533293
M. Thomas P. Gilbert9837633751
Lihua Xiao9349532721
Michael J. Wingfield93108543943
David Lloyd90101737691
Des R. Richardson8941830934
Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202323
2022154
20211,401
20201,281
20191,193
20181,111