Nagoya Institute of Technology

About: Nagoya Institute of Technology is a education organization based out in Nagoya, Japan. It is known for research contribution in the topics: Thin film & Turbulence. The organization has 10766 authors who have published 19140 publications receiving 255696 citations. The organization is also known as: Nagoya Kōgyō Daigaku & Nitech.

A remote surgery experiment between Japan and Thailand over Internet using a low latency CODEC system

Abstract: Remote surgery is one of the most desired applications in the context of recent advanced medical technologies. For a future expansion of remote surgery, it is important to use conventional network infrastructures such as Internet. However, using such conventional network infrastructures, we are confronting time-delay problems of data transmission. In this paper, a remote surgery experiment between Japan and Thailand using a research and development Internet is presented. In the experiment, the image and audio information was transmitted by a newly developed low latency CODEC system to shorten the time-delay. By introducing the low latency CODEC system, the time-delay was shortened compared with the past remote surgery experiments despite the longer distance. We also conducted several network measurements such as a comparison between TCP/IP and UDP/IP about the control signal transmission.

Structural basis of thalidomide enantiomer binding to cereblon.

Abstract: Thalidomide possesses two optical isomers which have been reported to exhibit different pharmacological and toxicological activities. However, the precise mechanism by which the two isomers exert their different activities remains poorly understood. Here, we present structural and biochemical studies of (S)- and (R)-enantiomers bound to the primary target of thalidomide, cereblon (CRBN). Our biochemical studies employed deuterium-substituted thalidomides to suppress optical isomer conversion, and established that the (S)-enantiomer exhibited ~10-fold stronger binding to CRBN and inhibition of self-ubiquitylation compared to the (R)-enantiomer. The crystal structures of the thalidomide-binding domain of CRBN bound to each enantiomer show that both enantiomers bind the tri-Trp pocket, although the bound form of the (S)-enantiomer exhibited a more relaxed glutarimide ring conformation. The (S)-enantiomer induced greater teratogenic effects on fins of zebrafish compared to the (R)-enantiomer. This study has established a mechanism by which thalidomide exerts its effects in a stereospecific manner at the atomic level.

Instantaneous torque analysis of hybrid stepping motor

Abstract: The hybrid stepping motor is promising as a high-torque and low-speed servomotor, since the motor can be considered as a multipole synchronous motor. For this application, it is necessary to have a clear equivalent circuit under the sinusoidal current drive just like the conventional brushless DC motor. For the given stator/rotor teeth and winding arrangements of the hybrid stepping motor, the permeance distribution with respect to the rotor position is obtained by a well-known permeance-based method. Based on the calculated permeance distribution, an equivalent magnetic circuit of the given motor can be obtained, from which the basic voltage equation can be deduced. Following this procedure, electric parameters in the voltage equation are related to the machine construction constants such as stator-rotor pole dimensions, air-gap length, number of turns of the stator windings, and magnetomotive force (MMF) of the permanent magnet. The analysis shows that a fundamental component of the permeance distribution produces the average torque and that harmonic components produce the ripple torque under the sinusoidal current drives. The cogging torque is also produced by the 4th harmonic component of the permeance distribution. For the laboratory testing, the two-phase hybrid stepping motor connected to the current-controlled voltage source inverter was used. The experimental results showed quite reasonable agreement with the predicted instantaneous torque.