Nagoya Institute of Technology

About: Nagoya Institute of Technology is a education organization based out in Nagoya, Japan. It is known for research contribution in the topics: Thin film & Catalysis. The organization has 10766 authors who have published 19140 publications receiving 255696 citations. The organization is also known as: Nagoya Kōgyō Daigaku & Nitech.

Prediction of Information Diffusion Probabilities for Independent Cascade Model

Abstract: We address a problem of predicting diffusion probabilities in complex networks. As one approach to this problem, we focus on the independent cascade (IC) model, and define the likelihood for information diffusion episodes, where an episode means a sequence of newly active nodes. Then, we present a method for predicting diffusion probabilities by using the EM algorithm. Our experiments using a real network data set show the proposed method works well.

Speech Synthesis Based on Hidden Markov Models

Abstract: This paper gives a general overview of hidden Markov model (HMM)-based speech synthesis, which has recently been demonstrated to be very effective in synthesizing speech. The main advantage of this approach is its flexibility in changing speaker identities, emotions, and speaking styles. This paper also discusses the relation between the HMM-based approach and the more conventional unit-selection approach that has dominated over the last decades. Finally, advanced techniques for future developments are described.

Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

Abstract: New methods for preparation of tailor-made fluorine-containing compounds are in extremely high demand in nearly every sector of chemical industry. The asymmetric construction of quaternary C–F stereogenic centers is the most synthetically challenging and, consequently, the least developed area of research. As a reflection of this apparent methodological deficit, pharmaceutical drugs featuring C–F stereogenic centers constitute less than 1% of all fluorine-containing medicines currently on the market or in clinical development. Here we provide a comprehensive review of current research activity in this area, including such general directions as asymmetric electrophilic fluorination via organocatalytic and transition-metal catalyzed reactions, asymmetric elaboration of fluorine-containing substrates via alkylations, Mannich, Michael, and aldol additions, cross-coupling reactions, and biocatalytic approaches.