Institution
Nanjing University
Education•Nanjing, China•
About: Nanjing University is a education organization based out in Nanjing, China. It is known for research contribution in the topics: Catalysis & Adsorption. The organization has 85961 authors who have published 105504 publications receiving 2289036 citations. The organization is also known as: NJU & Nanking University.
Topics: Catalysis, Adsorption, Population, Computer science, Thin film
Papers published on a yearly basis
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386 citations
TL;DR: Microplastics caused multiple toxic effects in fish intestine, including mucosal damage, and increased permeability, inflammation and metabolism disruption, and it is suggested that shape-depended effects should not be ignored in the health risk assessment of microplastics.
382 citations
TL;DR: In this article, the authors give answers to the questions of timing, tectonic style and geodynamic interpretation of south China geologic development, which implies two successive suturings of oceanic domains during the Middle-Late Proterozoic: one about 1500 Ma and one about 950 Ma.
381 citations
TL;DR: This review presents a comprehensive and up-to-date overview on the therapeutic stimuli-responsive metallodrugs that have appeared in the past two decades, where stimuli such as redox, pH, enzyme, light, temperature, and so forth were involved.
Abstract: The success of platinum-based anticancer agents has motivated the exploration of novel metal-based drugs for several decades, whereas problems such as drug-resistance and systemic toxicity hampered their clinical applications and efficacy. Stimuli-responsiveness of some metal complexes offers a good opportunity for designing site-specific prodrugs to maximize the therapeutic efficacy and minimize the side effect of metallodrugs. This review presents a comprehensive and up-to-date overview on the therapeutic stimuli-responsive metallodrugs that have appeared in the past two decades, where stimuli such as redox, pH, enzyme, light, temperature, and so forth were involved. The compounds are classified into three major categories based on the nature of stimuli, that is, endo-stimuli-responsive metallodrugs, exo-stimuli-responsive metallodrugs, and dual-stimuli-responsive metallodrugs. Representative examples of each type are discussed in terms of structure, response mechanism, and potential medical applications. In the end, future opportunities and challenges in this field are tentatively proposed. With diverse metal complexes being introduced, the foci of this review are pointed to platinum and ruthenium complexes.
381 citations
TL;DR: The toxicity of the photolysis compounds was evaluated using luminescent bacterium, and the results revealed that the toxicity increased with irradiation, indicative of a higher adversity risk of the degradation products of TC on bacteria uponphotolysis.
380 citations
Authors
Showing all 86514 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Yi Chen | 217 | 4342 | 293080 |
| H. S. Chen | 179 | 2401 | 178529 |
| Zhenan Bao | 169 | 865 | 106571 |
| Gang Chen | 167 | 3372 | 149819 |
| Peter G. Schultz | 156 | 893 | 89716 |
| Xiang Zhang | 154 | 1733 | 117576 |
| Rui Zhang | 151 | 2625 | 107917 |
| Yi Yang | 143 | 2456 | 92268 |
| Markku Kulmala | 142 | 1487 | 85179 |
| Jian Yang | 142 | 1818 | 111166 |
| Wei Huang | 139 | 2417 | 93522 |
| Bin Liu | 138 | 2181 | 87085 |
| Jun Lu | 135 | 1526 | 99767 |
| Hui Li | 135 | 2982 | 105903 |
| Lei Zhang | 135 | 2240 | 99365 |