National Autonomous University of Mexico

About: National Autonomous University of Mexico is a education organization based out in Mexico City, Distrito Federal, Mexico. It is known for research contribution in the topics: Population & Galaxy. The organization has 72868 authors who have published 127797 publications receiving 2285543 citations. The organization is also known as: UNAM & Universidad Nacional Autónoma de México.

Clump morphology and evolution in MHD simulations of molecular cloud formation

Abstract: We study the properties of clumps formed in three-dimensional weakly magnetized magnetohydrodynamic simulations of converging flows in the thermally bistable, warm neutral medium (WNM). We find the following. (1) Similarly to the situation in the classical two-phase medium, cold, dense clumps form through dynamically triggered thermal instability in the compressed layer between the convergent flows, and are often characterized by a sharp density jump at their boundaries though not always. (2) However, the clumps are bounded by phase-transition fronts rather than by contact discontinuities, and thus they grow in size and mass mainly by accretion of WNM material through their boundaries. (3) The clump boundaries generally consist of thin layers of thermally unstable gas, but these layers are often widened by the turbulence, and penetrate deep into the clumps. (4) The clumps are approximately in both ram and thermal pressure balance with their surroundings, a condition which causes their internal Mach numbers to be comparable to the bulk Mach number of the colliding WNM flows. (5) The clumps typically have mean temperatures 20 ≲〈T〉≲ 50 K, corresponding to the wide range of densities they contain (20 ≲n≲ 5000 cm−3) under a nearly isothermal equation of state. (6) The turbulent ram pressure fluctuations of the WNM induce density fluctuations that then serve as seeds for local gravitational collapse within the clumps. (7) The velocity and magnetic fields tend to be aligned with each other within the clumps, although both are significantly fluctuating, suggesting that the velocity tends to stretch and align the magnetic field with it. (8) The typical mean field strength in the clumps is a few times larger than that in the WNM. (9) The magnetic field strength in the densest regions within the clumps (n∼ 104 cm−3) has a mean value of B∼ 6 μG but with a large scatter of nearly two orders of magnitude, implying that both sub- and supercritical cores are formed in the simulation. (10) In the final stages of the evolution, the clumps' growth drives them into gravitational instability, at which point star formation sets in, and the pressure in the clumps' centres increases even further.

Proinflammatory and cytotoxic effects of Mexico City air pollution particulate matter in vitro are dependent on particle size and composition.

Abstract: Exposure to urban airborne particulate matter (PM) is associated with adverse health effects. We previously reported that the cytotoxic and proinflammatory effects of Mexico City PM10 (less than or equal to 10 micro m mean aerodynamic diameter) are determined by transition metals and endotoxins associated with these particles. However, PM2.5 (less than or equal to 2.5 micro m mean aerodynamic diameter) could be more important as a human health risk because this smaller PM has the potential to reach the distal lung after inhalation. In this study, we compared the cytotoxic and proinflammatory effects of Mexico City PM10 with those of PM2.5 using the murine monocytic J774A.1 cell line in vitro. PMs were collected from the northern zone or the southeastern zone of Mexico City. Elemental composition and bacterial endotoxin on PMs were measured. Tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) production by J774A.1 cells was measured in the presence or absence of recombinant endotoxin-neutralizing protein (rENP). Both northern and southeastern PMs contained endotoxin and a variety of transition metals. Southeastern PM10 contained the highest endotoxin levels, 2-fold higher than that in northern PM10. Northern and southeastern PM2.5 contained the lowest endotoxin levels. Accordingly, southeastern PM10 was the most potent in causing secretion of the proinflammatory cytokines TNF-alpha and IL-6. All PM2.5 and PM10 samples caused cytotoxicity, but northern PMs were the most toxic. Cytokine secretion induced by southeastern PM10 was reduced 50-75% by rENP. These results indicate major differences in PM10 and PM2.5. PM2.5 induces cytotoxicity in vitro through an endotoxin-independent mechanism that is likely mediated by transition metals. In contrast, PM10 with relatively high levels of endotoxin induces proinflammatory cytokine release via an endotoxin-dependent mechanism.