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Institution

National Autonomous University of Mexico

EducationMexico City, Distrito Federal, Mexico
About: National Autonomous University of Mexico is a education organization based out in Mexico City, Distrito Federal, Mexico. It is known for research contribution in the topics: Population & Galaxy. The organization has 72868 authors who have published 127797 publications receiving 2285543 citations. The organization is also known as: UNAM & Universidad Nacional Autónoma de México.


Papers
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Journal ArticleDOI
TL;DR: A previously unknown function of Oct4 in maintaining viability of mammalian germline is suggested using the conditional Cre/loxP gene targeting strategy to assess Oct4 function in primordial germ cells (PGCs).
Abstract: Previous studies have shown that Oct4 has an essential role in maintaining pluripotency of cells of the inner cell mass (ICM) and embryonic stem cells. However, Oct4 null homozygous embryos die around the time of implantation, thus precluding further analysis of gene function during development. We have used the conditional Cre/loxP gene targeting strategy to assess Oct4 function in primordial germ cells (PGCs). Loss of Oct4 function leads to apoptosis of PGCs rather than to differentiation into a trophectodermal lineage, as has been described for Oct4-deficient ICM cells. These new results suggest a previously unknown function of Oct4 in maintaining viability of mammalian germline.

554 citations

Journal ArticleDOI
TL;DR: In this paper, the centrality dependence of the chargedparticle multiplicity density at midrapidity in Pb-Pb collisions at root s(NN) = 2: 76 TeV is presented.
Abstract: The centrality dependence of the charged-particle multiplicity density at midrapidity in Pb-Pb collisions at root s(NN) = 2: 76 TeV is presented. The charged-particle density normalized per participating nucleon pair increases by about a factor of 2 from peripheral (70%-80%) to central (0%-5%) collisions. The centrality dependence is found to be similar to that observed at lower collision energies. The data are compared with models based on different mechanisms for particle production in nuclear collisions.

553 citations

Journal ArticleDOI
TL;DR: In this article, a review of different regimes for fidelity decay in quantum information processes is presented, and some important applications and experiments are discussed, using time correlation functions as a backbone for the discussion.

553 citations

Journal ArticleDOI
01 Feb 1995-Neuron
TL;DR: The differential regulation of HVA currents by the D1 pathway helps to explain the diversity of effects this pathway has on synaptic integration and plasticity in medium spiny neurons.

552 citations

Journal ArticleDOI
TL;DR: Growing evidence supports a role of ROS-induced generation of oxidative stress in these epigenetic processes and as such the authors can hypothesize of potential mode(s) of action) by which oxidative stress modulates epigenetic regulation of gene expression.

551 citations


Authors

Showing all 73617 results

NameH-indexPapersCitations
Richard Peto183683231434
Anton M. Koekemoer1681127106796
Rory Collins162489193407
Timothy C. Beers156934102581
Vivek Sharma1503030136228
Kjell Fuxe142147989846
Prashant V. Kamat14072579259
Carmen García139150396925
Harold A. Mooney135450100404
Efe Yazgan12898679041
Roberto Maiolino12781661724
Peter Nugent12775492988
William R. Miller12560172570
Nicholas A. Kotov12357455210
John C. Wingfield12250952291
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023311
2022967
20217,481
20207,906
20197,107