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Institution

National Autonomous University of Mexico

EducationMexico City, Distrito Federal, Mexico
About: National Autonomous University of Mexico is a education organization based out in Mexico City, Distrito Federal, Mexico. It is known for research contribution in the topics: Population & Galaxy. The organization has 72868 authors who have published 127797 publications receiving 2285543 citations. The organization is also known as: UNAM & Universidad Nacional Autónoma de México.


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Journal ArticleDOI
TL;DR: Results provide the first direct evidence to support a novel and central role of ABA in plant glucose responses mediated through glucose regulation of both ABA levels by GIN5 and ABA signaling byGIN6/ABI4.
Abstract: Sugars have signaling roles in a wide variety of developmental processes in plants. To elucidate the regulatory components that constitute the glucose signaling network governing plant growth and development, we have isolated and characterized two Arabidopsis glucose insensitive mutants, gin5 and gin6, based on a glucose-induced developmental arrest during early seedling morphogenesis. The T-DNA-tagged gin6 mutant abrogates the glucose-induced expression of a putative transcription factor, ABI4, previously shown to be involved in seed-specific abscisic acid (ABA) responses. Thus, ABI4 might be a regulator involved in both glucose- and seed-specific ABA signaling. The characterization of the gin5 mutant, on the other hand, reveals that glucose-specific accumulation of ABA is essential for hexokinase-mediated glucose responses. Consistent with this result, we show that three ABA-deficient mutants (aba1-1, aba2-1, and aba3-2) are also glucose insensitive. Exogenous ABA can restore normal glucose responses in gin5 and aba mutants but not in gin6 plants. Surprisingly, only abi4 and abi5-1 but not other ABA-insensitive signaling mutants (abi1-1, abi2-1, and abi3-1) exhibit glucose insensitivity, indicating the involvement of a distinct ABA signaling pathway in glucose responses. These results provide the first direct evidence to support a novel and central role of ABA in plant glucose responses mediated through glucose regulation of both ABA levels by GIN5 and ABA signaling by GIN6/ABI4.

501 citations

Journal ArticleDOI
TL;DR: In this article, the authors present an integrated landscape approach to promote research in human-modified landscapes that includes the effects of landscape structure and dynamics on conservation of biodiversity, provision of ecosystem services, and sustainability of rural livelihoods.
Abstract: To truly understand the current status of tropical diversity and to forecast future trends, we need to increase emphasis on the study of biodiversity in rural landscapes that are actively managed or modified by people. We present an integrated landscape approach to promote research in human-modified landscapes that includes the effects of landscape structure and dynamics on conservation of biodiversity, provision of ecosystem services, and sustainability of rural livelihoods. We propose research priorities encompassing three major areas: biodiversity, human–environment interactions, and restoration ecology. We highlight key areas where we lack knowledge and where additional understanding is most urgent for promoting conservation and sustaining rural livelihoods. Finally, we recommend participatory and multidisciplinary approaches in research and management. Lasting conservation efforts demand new alliances among conservation biologists, agroecologists, agronomists, farmers, indigenous peoples, rural social movements, foresters, social scientists, and land managers to collaborate in research, co-design conservation programs and policies, and manage human-modified landscapes in ways that enhance biodiversity conservation and promote sustainable livelihoods.

500 citations

Journal ArticleDOI
TL;DR: In this article, the electronic properties and the geometric structure of noble metal clusters were studied and the trend for the cohesive energy, ionization potentials, electron affinities, and highest accupied and lowest unoccupied molecular orbital gap was analyzed in detail for each noble metal and rationalized in terms of two-and three-dimensional electronic shell models.
Abstract: We present a systematic study of the electronic properties and the geometric structure of noble metal clusters ${X}_{n}^{\ensuremath{ u}}$ ($X=\mathrm{Cu}$, Ag, Au; $\ensuremath{ u}=\ensuremath{-}1,0,+1$; $n\ensuremath{\leqslant}13$ and $n=20$), obtained from first-principles generalized gradient approximation density functional calculations based on norm-conserving pseudopotentials and numerical atomic basis sets. We obtain planar structures for the ground state of anionic $(\ensuremath{ u}=\ensuremath{-}1)$, neutral $(\ensuremath{ u}=0)$, and cationic $(\ensuremath{ u}=1)$ species of gold clusters with up to 12, 11, and 7 atoms, respectively. In contrast, the maximum size of planar clusters with $\ensuremath{ u}=\ensuremath{-}1,0,+1$ are $n=(5,6,5)$ for silver and (5,6,4) for copper. For ${X}_{20}$ we find a ${T}_{d}$ symmetry for gold and a compact ${C}_{s}$ structure for silver and copper. Our results for the cluster geometries agree partially with previous first-principles calculations, and they are in good agreement with recent experimental results for anionic and cationic gold clusters. The tendency to planarity of gold clusters, which is much larger than in copper and silver, is strongly favored by relativistic effects, which decrease the $s\text{\ensuremath{-}}d$ promotion energy and lead to hybridization of the half-filled $6s$ orbital with the fully occupied $5{d}_{{z}^{2}}$ orbital. That picture is substantiated by analyzing our calculated density matrix for planar and three-dimensional clusters of gold and copper. The trends for the cohesive energy, ionization potentials, electron affinities, and highest accupied and lowest unoccupied molecular orbital gap, as the cluster size increases, are studied in detail for each noble metal and rationalized in terms of two- and three-dimensional electronic shell models. The most probable fragmentation channels for ${X}_{n}^{\ensuremath{ u}}$ clusters are in very good agreement with available experiments.

500 citations

Journal ArticleDOI
TL;DR: In this article, the authors present the first observation of strangeness enhancement in high-multiplicity proton-proton collisions, showing that the integrated yields of strange and multi-strange particles relative to pions increases significantly with the event charged-particle multiplicity.
Abstract: At sufficiently high temperature and energy density, nuclear matter undergoes a transition to a phase in which quarks and gluons are not confined: the quark-gluon plasma (QGP). Such an exotic state of strongly interacting quantum chromodynamics matter is produced in the laboratory in heavy nuclei high-energy collisions, where an enhanced production of strange hadrons is observed. Strangeness enhancement, originally proposed as a signature of QGP formation in nuclear collisions, is more pronounced for multi-strange baryons. Several effects typical of heavy-ion phenomenology have been observed in high-multiplicity proton-proton (pp) collisions, but the enhanced production of multi-strange particles has not been reported so far. Here we present the first observation of strangeness enhancement in high-multiplicity proton-proton collisions. We find that the integrated yields of strange and multi-strange particles, relative to pions, increases significantly with the event charged-particle multiplicity. The measurements are in remarkable agreement with the p-Pb collision results, indicating that the phenomenon is related to the final system created in the collision. In high-multiplicity events strangeness production reaches values similar to those observed in Pb-Pb collisions, where a QGP is formed.

500 citations

Journal ArticleDOI
TL;DR: A review of species commonly used in México in the treatment of diabetes mellitus, highlighting the current knowledge about these botanicals, but also the enormous gaps in knowledge as it relates to the species' toxicology, the pharmacokinetics of its active constituents and their metabolism.

498 citations


Authors

Showing all 73617 results

NameH-indexPapersCitations
Richard Peto183683231434
Anton M. Koekemoer1681127106796
Rory Collins162489193407
Timothy C. Beers156934102581
Vivek Sharma1503030136228
Kjell Fuxe142147989846
Prashant V. Kamat14072579259
Carmen García139150396925
Harold A. Mooney135450100404
Efe Yazgan12898679041
Roberto Maiolino12781661724
Peter Nugent12775492988
William R. Miller12560172570
Nicholas A. Kotov12357455210
John C. Wingfield12250952291
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023311
2022967
20217,481
20207,906
20197,107