National Autonomous University of Nicaragua

About: National Autonomous University of Nicaragua is a education organization based out in Managua, Nicaragua. It is known for research contribution in the topics: Population & Public health. The organization has 775 authors who have published 715 publications receiving 9791 citations.

The Assessment of Occupational Exposure to Diazinon in Nicaraguan Plantation Workers Using Saliva Biomonitoring

Abstract: A cross-sectional study with repeated sample collection in multiple days was conducted to assess diazinon exposures. Saliva and limited blood samples were collected from 10 banana plantation workers involved with diazinon application and their children aged 2-12 years living in Chinandega, Nicaragua. Diazinon concentration-time profiles in saliva varied between two plantations, which reflects the differences of work practices in each plantation. Salivary concentrations of diazinon measured in Plantation 1 applicators continued to increase 2 days after self-reported diazinon application, suggesting an ongoing exposure among these workers. However, salivary diazinon concentrations measured in Plantation 2 applicators were peaked 12 h prior to the first application, and then decreased 36 h post the first application. Diazinon concentrations in saliva were significantly correlated with the time-matched plasma samples collected from the same workers, which is in agreement with the previous published data from animal models. Children's exposure to diazinon through take-home pathway does not exist, as evident by the majority of nondetected saliva samples, and this finding was confirmed by the results from the urine samples. Severe dehydration was observed in many plantation workers and their children, resulting in the loss of some saliva samples, which no doubt have impaired the overall quality of the study results. Regardless, this article has demonstrated that saliva can be used to assess exposures to diazinon in pesticide applicators and children.

La calidad de la educación superior y su acreditación: la experiencia centroamericana

Abstract: This chapter presents a comparative study of the accreditation processes in Central America and of the institutions that are responsible for developing them.

Rationale, description and baseline findings of a community-based prospective cohort study of kidney function amongst the young rural population of Northwest Nicaragua.

Abstract: An epidemic of Mesoamerican Nephropathy (MeN) is killing thousands of agricultural workers along the Pacific coast of Central America, but the natural history and aetiology of the disease remain poorly understood. We have recently commenced a community-based longitudinal study to investigate Chronic Kidney Disease (CKD) in Nicaragua. Although logistically challenging, study designs of this type have the potential to provide important insights that other study designs cannot. In this paper we discuss the rationale for conducting this study and summarize the findings of the baseline visit. The baseline visit of the community-based cohort study was conducted in 9 communities in the North Western Nicaragua in October and November 2014. All of the young men, and a random sample of young women (aged 18–30) without a pre-existing diagnosis of CKD were invited to participate. Glomerular filtration rate (eGFR) was estimated with CKD-EPI equation, along with clinical measurements, questionnaires, biological and environmental samples to evaluate participants’ exposures to proposed risk factors for MeN. We identified 520 young adults (286 males and 234 females) in the 9 different communities. Of these, 16 males with self-reported CKD and 5 females with diagnoses of either diabetes or hypertension were excluded from the study population. All remaining 270 men and 90 women, selected at random, were then invited to participate in the study; 350 (97%) agreed to participate. At baseline, 29 (11%) men and 1 (1%) woman had an eGFR <90 mL/min/1.73 m2. Conducting a community based study of this type requires active the involvement of communities and commitment from local leaders. Furthermore, a research team with strong links to the area and broad understanding of the context of the problem being studied is essential. The key findings will arise from follow-up, but it is striking that 5% of males under aged 30 had to be excluded because of pre-existing kidney disease, and that despite doing so 11% of males had an eGFR <90 mL/min/1.73 m2 at baseline.

Desigualdades socioeconómicas en salud bucal: Factores asociados a la frecuencia de cepillado dental en escolares nicaragüenses

Abstract: Objective. To identify the association between tooth brushing frequency and variables of socioeconomic position in Nicaraguan schoolchildren. Material and Methods. A cross sectional study was undertaken in 1353 schoolchildren ages 6 to 12 randomly selected from 25 elementary schools in Leon, Nicaragua. Using a questionnaire addressed to mothers, sociodemographic, socioeconomic and behavioral variables were collected. The dependent variable was tooth brushing frequency, which was dichotomized in 0 “at least one 7 times/week” and 1 “7 or more times/week”. A multivariate analysis was carried out with logistic regression in STATA 9. Results. The average age of child participants was 8.99 ± 2.00 years and 49.7% were women. In the final model, older age (OR = 2.04), female sex (OR = 1.39) and having a mother with positive attitudes toward oral health (OR = 2.5) were positively associated with the tooth brushing frequency (p < 0.05). Larger family size (OR = 0.89) and having low socioeconomic status (1st quartile; OR = 0.54, 2nd quartile; OR = 0.62, 3rd quartile; OR = 0.67) showed a negative relationship with the tooth brushing frequency. To have had at least one preventive dental visit in the previous year was positively associated (p < 0.10) with tooth brushing frequency. Conclusion. This study suggested that existence of indicators of socioeconomic inequalities exist even within less developed countries, and thus emphasize the need to target health promotion programs to vulnerable socioeconomic groups.