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Institution

National Chemical Laboratory

FacilityPune, Maharashtra, India
About: National Chemical Laboratory is a facility organization based out in Pune, Maharashtra, India. It is known for research contribution in the topics: Catalysis & Enantioselective synthesis. The organization has 8891 authors who have published 14837 publications receiving 387600 citations.


Papers
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Journal ArticleDOI
TL;DR: The endo:exo ratio of 0.35:1 for the reaction of cyclopentadiene with methyl methacrylate observed in organic solvents can be converted to 3:1 in chloroaluminate ionic liquids with their effective reuse in Diels-Alder reactions.
Abstract: The endo:exo ratio of 0.35:1 for the reaction of cyclopentadiene with methyl methacrylate observed in organic solvents can be converted to 3:1 in chloroaluminate ionic liquids with their effective reuse in Diels-Alder reactions.

119 citations

Journal ArticleDOI
TL;DR: The over-expression of this gene in chickpea could act as an endogenous source of resistance to H. armigera, and form a distinct phylogenetic cluster with Kunitz inhibitors from Glycine max, Medicago truncatula, P. sativum and Canavalia lineata.
Abstract: Chickpea (Cicer arietinum L.) seeds contain Bowman–Birk proteinase inhibitors, which are ineffective against the digestive proteinases of larvae of the insect pest Helicoverpa armigera. We have identified and purified a low expressing proteinase inhibitor (PI), distinct from the Bowman–Birk Inhibitors and active against H. armigera gut proteinases (HGP), from chickpea seeds. N-terminal sequencing of this HGP inhibitor revealed a sequence similar to reported pea (Pisum sativum) and chickpea α-l-fucosidases and also homologous to legume Kunitz inhibitors. The identity was confirmed by matrix assisted laser desorption ionization – time of flight analysis of tryptic peptides and isolation of DNA sequence coding for the mature protein. Available sequence data showed that this protein forms a distinct phylogenetic cluster with Kunitz inhibitors from Glycine max, Medicago truncatula, P. sativum and Canavalia lineata. The isolated coding sequence was cloned into a yeast expression vector and produced as a recombinant protein in Pichia pastoris. α-l-fucosidase activity was not detectable in purified or recombinant protein, by solution assays. The recombinant protein did not inhibit chymotrypsin or subtilisin activity but did exhibit stoichiometric inhibition of trypsin, comparable to soybean Kunitz trypsin inhibitor. The recombinant protein exhibited higher inhibition of total HGP activity as compared to soybean kunitz inhibitor, even though it preferentially inhibited HGP-trypsins. H. armigera larvae fed on inhibitor-incorporated artificial diet showed significant reduction in average larval weight after 18 days of feeding demonstrating potent antimetabolic activity. The over-expression of this gene in chickpea could act as an endogenous source of resistance to H. armigera.

118 citations

Journal ArticleDOI
TL;DR: Nine compounds isolated from the aerial parts of Andrographis paniculata and their structures were established by spectral data and all the isolates were tested for the anti-HIV and cytotoxic activity.

118 citations

Journal ArticleDOI
18 Sep 1999-Langmuir
TL;DR: A detailed investigation of the diffusion of carboxylic acid derivatized gold colloidal particles of different sizes into thermally evaporated octadecylamine films using quartz crystal microgravimetry (QCM), transmission electron microscopy, and UV−vis absorption and Fourier transform infrared (FTIR) spectroscopies is described in this paper.
Abstract: We have recently shown that nanocomposites of colloidal particles in a fatty lipid matrix can be grown via a diffusion process controlled by selective electrostatic interactions In this paper, a detailed investigation of the diffusion of carboxylic acid derivatized gold colloidal particles of different sizes into thermally evaporated octadecylamine films using quartz crystal microgravimetry (QCM), transmission electron microscopy, and UV−vis absorption and Fourier transform infrared (FTIR) spectroscopies is described The QCM kinetics of gold cluster incorporation has been analyzed in terms of a one-dimensional Fickian-type diffusion model, and it is found that the cluster diffusivity increases with decreasing cluster size The pH at which maximum cluster incorporation in the amine occurs was found to be dependent on the cluster size as well FTIR spectroscopy of the fatty amine-gold particle composites indicated weak coupling of the clusters to the protonated amine groups as well as interesting cluster

118 citations

Journal ArticleDOI
TL;DR: The fiber mats exhibit a significantly enhanced dynamic strain sensor response and are exhibiting a non-linearly enhanced performance vis a vis the increase in the β phase component.
Abstract: PVDF nanofibers are prepared using electrospinning. The effect of addition of a hydrated salt, nickel chloride hexahydrate (NiCl2·6H2O), on the phase formation is examined. Addition of the hydrated salt (NC) is found to enhance the polar β phase by about 30%. The peak to peak piezo-voltage generated for PVDF NC is almost 0.762 V, a factor of 3 higher than that for PVDF. The fiber mats exhibit a significantly enhanced dynamic strain sensor response. The voltage generated per unit micro-strain developed during the free vibration test for PVDF was 0.119 mV whereas it was 0.548 mV for PVDF NC, exhibiting a non-linearly enhanced performance vis a vis the increase in the β phase component.

118 citations


Authors

Showing all 8913 results

NameH-indexPapersCitations
Ashok Kumar1515654164086
Rajesh Kumar1494439140830
Tak W. Mak14880794871
John T. O'Brien12181963242
Clive Ballard11773661663
Yoshinori Tokura11785870258
John S. Mattick11636764315
Michael Dean10741963335
Ian G. McKeith10746851954
David J. Burn10044639120
Anil Kumar99212464825
Vikas Kumar8985939185
Detlef W. Bahnemann8851748826
Gautam R. Desiraju8845845301
Praveen Kumar88133935718
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20236
202238
2021482
2020454
2019471
2018498