National Jewish Health

About: National Jewish Health is a healthcare organization based out in Denver, Colorado, United States. It is known for research contribution in the topics: Asthma & T cell. The organization has 883 authors who have published 833 publications receiving 79201 citations. The organization is also known as: National Jewish Medical and Research Center.

No one can work with her

Abstract: Agitation is common across all forms of dementia and is often associated with other behavioral and psychological symptoms of dementia (BPSD), including anxiety, depression, and psychosis. A helpful algorithm to manage agitation is DICE, which stands for Describe, Investigate, Create, and Evaluate. The best management strategy starts with a clear understanding of the context for the behaviors, including causes and responses, and uses medical and psychiatric exams to help identify these. Non-pharmacological approaches are considered the first line of treatment. Pharmacologic approaches must be carefully considered in terms of risks and benefits. It is important to re-evaluate the treatment response and adjust the plan accordingly.

Compositions and methods to induce targeted apoptosis

Abstract: Embodiments herein concern compositions and methods for treating a subject having or suspected of developing a pulmonary disorder or cancer. Certain embodiments concern modulating protein tyrosine phosphatase non-receptor type 13 (PTPN13) expression and/or activity in a subject to treat uncontrolled cellular growth in the subject.

Stem and Progenitor Cells of the Airway Epithelium

Abstract: This chapter argues that the hierarchical stem cell model should be adapted to reflect the specialized progenitor cell types that maintain the conducing airway epithelium. The conducting airway epithelium serves as the interface between the lung and the environment. Basic epithelial functions, such as barrier maintenance, are characteristic of all airway regions. However, other epithelial activities that are necessary to protect the lung from the environment vary along the proximal to distal axis of the airway. These adaptive modifications are manifest as differences in cellular composition and in the structure/function of specific cell types. Studies in humans and mice suggest that this specialization is a consequence of distinct progenitor cell pools. Each pool includes a tissue-specific stem cell and one or more facultative progenitor cell types. Facultative progenitors perform differentiated functions in the steady state but maintain the ability to proliferate in response to cellular injury. We propose that the facultative progenitor cells comprise a unique tier(s) within distinct stem cell hierarchies that maintain the proximal and distal conducing airway epithelium

Treatment for airway cast obstruction

Abstract: The present invention is directed to methods of treatment of airway obstruction associated with fibrin-containing cast formation by administering a fibrinolytic agent.