Institution
National Ocean Service
Government•Silver Spring, Maryland, United States•
About: National Ocean Service is a government organization based out in Silver Spring, Maryland, United States. It is known for research contribution in the topics: Algal bloom & Population. The organization has 500 authors who have published 643 publications receiving 46096 citations.
Topics: Algal bloom, Population, Brevetoxin, Domoic acid, Karenia brevis
Papers published on a yearly basis
Papers
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TL;DR: It is demonstrated that SPATT samplers using HP20 resin coupled with PP2A technology could be used to provide early warning of DSP, but not PSP, events for shellfish management.
Abstract: Marine biotoxin-contaminated seafood has caused thousands of poisonings worldwide this century. Given these threats, there is an increasing need for improved technologies that can be easily integrated into coastal monitoring programs. This study evaluates approaches for monitoring toxins associated with recurrent toxin-producing Alexandrium and Dinophysis blooms on Long Island, NY, USA, which cause paralytic and diarrhetic shellfish poisoning (PSP and DSP), respectively. Within contrasting locations, the dynamics of pelagic Alexandrium and Dinophysis cell densities, toxins in plankton, and toxins in deployed blue mussels (Mytilus edulis) were compared with passive solid-phase adsorption toxin tracking (SPATT) samplers filled with two types of resin, HP20 and XAD-2. Multiple species of wild shellfish were also collected during Dinophysis blooms and used to compare toxin content using two different extraction techniques (single dispersive and double exhaustive) and two different toxin analysis assays (liquid chromatography/mass spectrometry and the protein phosphatase inhibition assay (PP2A)) for the measurement of DSP toxins. DSP toxins measured in the HP20 resin were significantly correlated (R2 = 0.7–0.9, p 0.05), were highly correlated (R2 = 0.98–0.99; p < 0.001) and provided complete recovery of DSP toxins from standard reference materials. Blue mussels (Mytilus edulis) and ribbed mussels (Geukensia demissa) were found to accumulate DSP toxins above federal and international standards (160 ng g−1) during Dinophysis blooms while Eastern oysters (Crassostrea virginica) and soft shell clams (Mya arenaria) did not. This study demonstrated that SPATT samplers using HP20 resin coupled with PP2A technology could be used to provide early warning of DSP, but not PSP, events for shellfish management.
22 citations
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TL;DR: Results suggest that gene expression profile analysis may provide a valuable means to screen for indicators of chemical exposure in dolphins through the immunological and/or endocrine perturbations associated with these agents.
22 citations
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TL;DR: This compound is the first reported cytotoxic natural product isolated and fully characterized from a Trichodesmium species and possesses cytotoxicity activity against GH(4)C(1) rat pituitary and Neuro-2a mouse neuroblastoma cells.
Abstract: Trichodesmium is a suspected toxin-producing nonheterocystous cyanobacteria ubiquitous in tropical, subtropical, and temperate seas. The genus is known for its ability to fix nitrogen and form massive blooms. In oligotrophic seas, it can dominate the biomass and be a major component of oceanic primary production and global nitrogen cycling. Numerous reports suggest Trichodesmium-derived toxins are a cause of death of fish, crabs, and bivalves. Laboratory studies have demonstrated neurotoxic effects in T. thiebautii cell extracts and field reports suggest respiratory distress and contact dermatitis of humans at collection sites. However, Trichodesmium toxins have not been identified and characterized. Here, we report the extraction of a lipophilic toxin from field-collected T. thiebautii using a purification method of several chromatographic techniques, nuclear magnetic resonance (NMR), mass spectroscopy (MS), and Fourier transformed-infrared spectroscopy (FT-IR). Trichotoxin has a molecular formula of C(20)H(27)ClO and a mass of 318 m/z and possesses cytotoxic activity against GH(4)C(1) rat pituitary and Neuro-2a mouse neuroblastoma cells. A detection method using liquid chromatography/mass spectrometry (LC/MS) was developed. This compound is the first reported cytotoxic natural product isolated and fully characterized from a Trichodesmium species.
22 citations
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01 Jan 2005-Journal of Environmental Science and Health Part B-pesticides Food Contaminants and Agricultural Wastes
TL;DR: It is demonstrated that synergized resmethrin is more toxic to P. pugio than the nonsynergized form, and that the presence of sediment decreases the toxicity of both res methrin and Scourge.
Abstract: This study investigated the toxicity of various concentrations of technical resmethrin and Scourge® on adult and larval Palaemonetes pugio, a common grass shrimp species. Two types of tests were conducted for each of the resmethrin formulations using adult and larval grass shrimp life stages, a 96-h static renewal aqueous test without sediment, and a 24-h static nonrenewal aqueous test with sediment. For resmethrin, the 96-h aqueous LC50 value for adult shrimp was 0.53 μg/L (95% confidence interval (CI): 0.46–0.60 μg/L), and for larval shrimp was 0.35 μg/L (95% CI: 0.28–0.42 μg/L). In the presence of sediment, technical resmethrin produced a 24-h LC50 value for adult shrimp of 5.44 μg/L (95% CI: 4.52–6.55 μg/L), and for larval shrimp of 2.15 μg/L (95% CI: 1.35–3.43 μg/L). For Scourge®, the 96-h aqueous LC50 for adult shrimp was 2.08 μg/L (95% CI: 1.70–2.54 μg/L), and for larval shrimp was 0.36 μg/L (95% CI: 0.24–0.55 μg/L). The 24-h sediment test yielded an LC50 value of 16.12 μg/L (95% CI: 14.79...
22 citations
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TL;DR: Results of the 24-h AChE inhibition tests showed that newly hatched larvae were generally more sensitive in the three organophosphate exposures, and sublethal effect endpoints could be used as a predictor of 96-h mortality.
22 citations
Authors
Showing all 501 results
Name | H-index | Papers | Citations |
---|---|---|---|
Charles H. Peterson | 77 | 202 | 28829 |
David T. Sandwell | 65 | 245 | 20058 |
William G. Sunda | 57 | 103 | 13933 |
Patricia A. Tester | 50 | 115 | 7012 |
James E. Byers | 49 | 137 | 9385 |
Jonathan A. Hare | 45 | 126 | 7259 |
Hunter S. Lenihan | 43 | 90 | 19833 |
Walter H. F. Smith | 42 | 111 | 30201 |
Richard P. Stumpf | 39 | 114 | 6034 |
Jonathan H. Grabowski | 39 | 120 | 5874 |
John S. Ramsdell | 39 | 115 | 4038 |
Patricia A. Fair | 38 | 115 | 3926 |
James C. Ryan | 37 | 101 | 5362 |
R. Wayne Litaker | 37 | 78 | 3947 |
Mark Busman | 36 | 84 | 4683 |