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Institution

National University of La Plata

EducationLa Plata, Argentina
About: National University of La Plata is a education organization based out in La Plata, Argentina. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 12993 authors who have published 30013 publications receiving 495118 citations. The organization is also known as: UNLP & Universidad Nacional de La Plata.


Papers
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Journal ArticleDOI
TL;DR: The preferential CO oxidation (CO-PROX) reaction is paramount for the purification of reformate H2-rich streams, where CuO/CeO2 catalysts show promising opportunities as mentioned in this paper.
Abstract: The preferential CO oxidation (CO-PROX) reaction is paramount for the purification of reformate H2-rich streams, where CuO/CeO2 catalysts show promising opportunities. This work sheds light on the ...

115 citations

Book ChapterDOI
TL;DR: In this paper, the influence of the Sn/Pt atomic ratio on the hydrogenation of cinnamaldehyde has been studied and an optimum of approximately 0.4 has been found.
Abstract: Silica supported bimetallic and organobimetallic PtSn catalysts were prepared by Surface Organometallic Chemistry on Metals and tested in the hydrogenation of different carbonylic compounds (butanal, butanone, cyclohexanone, benzaldehyde, crotonaldehyde and cinnamaldehyde). It was studied the influence of the Sn/Pt atomic ratio on the hydrogenation of cinnamaldehyde, having been found an optimum of approximately 0.4. The selective hydrogenation of C=O group in polyfunctional molecules can be explained on the basis of the combination of geometric (specially in organobimetallic catalysts), and electronic effects due to the presence of ionic tin.

114 citations

Journal ArticleDOI
TL;DR: In this paper, a numerical integration of the structure equations that describe Neutron Stars (NSs) in strong gravity was performed, and it was shown that these profiles run in correlation with the second-order derivative of the analytic approximation to the Equation of State (EoS).
Abstract: The effects implied for the structure of compact objects by the modification of General Relativity (GR) produced by the generalization of the Lagrangian density to the form $$f(R)=R+\alpha R^2$$ , where $$R$$ is the Ricci curvature scalar, have been recently explored. It seems likely that this squared-gravity may allow heavier Neutron Stars (NSs) than GR. In addition, these objects can be useful to constrain free parameters of modified-gravity theories. The differences between alternative gravity theories are enhanced in the strong gravitational regime. In this regime, because of the complexity of the field equations, perturbative methods become a good choice to treat the problem. Following previous works in the field, we performed a numerical integration of the structure equations that describe NSs in $$f(R)$$ -gravity, recovering their mass-radius relations, but focusing on particular features that arise from this approach in the profiles of the NS interior. We show that these profiles run in correlation with the second-order derivative of the analytic approximation to the Equation of State (EoS), which leads to regions where the enclosed mass decreases with the radius in a counter-intuitive way. We reproduce all computations with a simple polytropic EoS to separate zeroth-order modified gravity effects.

114 citations

Journal Article
TL;DR: The ligand properties of carnosine are analyzed in this paper, where the stoichiometry, stability constants, and structural and spectroscopic properties of its coordination compounds with transition and representative metal cations are discussed.
Abstract: The ligand properties of carnosine are analyzed. The stoichiometry, stability constants, and structural and spectroscopic characteristics of its coordination compounds with transition and representative metal cations are discussed. Mixed ligand systems containing carnosine are also presented. The biological activity of some of these metallic complexes is briefly considered.

114 citations

Journal ArticleDOI
TL;DR: Results suggest that the accumulation of AGE on bone extracellular matrix could regulate the proliferation and differentiation of osteoblastic cells, and possibly involve the modulation of NOS expression and intracellular ROS pathways.
Abstract: The tissue accumulation of protein-bound advanced glycation endproducts (AGE) may be involved in the etiology of diabetic chronic complications, including osteopenia. The aim of this study was to investigate the effect of an AGE-modified type I collagen substratum on the adhesion, spreading, proliferation and differentiation of rat osteosarcoma UMR106 and mouse non-transformed MC3T3E1 osteoblastic cells. We also studied the role of reactive oxygen species (ROS) and nitric oxide synthase (NOS) expression on these AGE-collagen mediated effects. AGE-collagen decreased the adhesion of UMR106 cells, but had no effect on the attachment of MC3T3E1 cells. In the UMR106 cell line, AGE-collagen also inhibited cellular proliferation, spreading and alkaline phosphatase (ALP) activity. In preosteoblastic MC3T3E1 cells (24-hour culture), proliferation and spreading were significantly increased by AGE-collagen. After one week of culture (differentiated MC3T3E1 osteoblasts) AGE-collagen inhibited ALP activity, but had no effect on cell number. In mineralizing MC3T3E1 cells (3-week culture) AGE-collagen induced a decrease in the number of surviving cells and of extracellular nodules of mineralization, without modifying their ALP activity. Intracellular ROS production, measured after a 48-hour culture, was decreased by AGE-collagen in MC3T3E1 cells, but was increased by AGE-collagen in UMR106 cells. After a 24-hour culture, AGE-collagen increased the expression of endothelial and inducible NOS, in both osteoblastic cell lines. These results suggest that the accumulation of AGE on bone extracellular matrix could regulate the proliferation and differentiation of osteoblastic cells. These effects appear to depend on the stage of osteoblastic development, and possibly involve the modulation of NOS expression and intracellular ROS pathways.

114 citations


Authors

Showing all 13198 results

NameH-indexPapersCitations
David Cameron1541586126067
Subir Sarkar1491542144614
Mayda Velasco137130987579
Diego F. Torres13794872180
Heidi Sandaker12899976517
Vincent Garonne12892176980
Farid Ould-Saada12893176394
Ole Røhne128103875752
Peter Hansen128127186210
Maria-Teresa Dova12777873558
Vladimir Sulin12788475329
Andrei Snesarev12787574907
James Catmore12789275086
Ruslan Mashinistov12686073897
Fernando Monticelli12684373385
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202333
2022315
20211,491
20201,738
20191,675
20181,527