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Institution

National University of La Plata

EducationLa Plata, Argentina
About: National University of La Plata is a education organization based out in La Plata, Argentina. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 12993 authors who have published 30013 publications receiving 495118 citations. The organization is also known as: UNLP & Universidad Nacional de La Plata.


Papers
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Journal ArticleDOI
A. Aab1, P. Abreu2, Marco Aglietta3, Markus Ahlers4  +501 moreInstitutions (67)
TL;DR: In this paper, the authors used the timing information from the flash analog-to-digital converter traces of surface detectors far from the air shower core to reconstruct a muon production depth distribution.
Abstract: The surface detector array of the Pierre Auger Observatory provides information about the longitudinal development of the muonic component of extensive air showers. Using the timing information from the flash analog-to-digital converter traces of surface detectors far from the shower core, it is possible to reconstruct a muon production depth distribution. We characterize the goodness of this reconstruction for zenith angles around 60 degrees and different energies of the primary particle. From these distributions, we define X-max(mu) as the depth along the shower axis where the production of muons reaches maximum. We explore the potentiality of X-max(mu) as a useful observable to infer the mass composition of ultrahigh-energy cosmic rays. Likewise, we assess its ability to constrain hadronic interaction models.

99 citations

Journal ArticleDOI
TL;DR: Data is presented demonstrating the effectiveness of endurance training to convert pathological into physiological hypertrophy improving cardiac performance and the reduction of myocardial fibrosis and calcineurin activity plus the increase in capillary density represent factors to be considered in determining this beneficial effect.
Abstract: The effect of endurance training (swimming 90 min/d for 5 days a week for 60 days) on cardiac hypertrophy was investigated in the spontaneously hypertensive rat (SHR). Sedentary SHRs (SHR-Cs) and normotensive Wistar rats were used as controls. Exercise training enhanced myocardial hypertrophy assessed by left ventricular weight/tibial length (228+/-7 versus 251+/-5 mg/cm in SHR-Cs and exercised SHRs [SHR-Es], respectively). Myocyte cross-sectional area increased approximately 40%, collagen volume fraction decreased approximately 50%, and capillary density increased approximately 45% in SHR-Es compared with SHR-Cs. The mRNA abundance of atrial natriuretic factor and myosin light chain 2 was decreased by the swimming routine (100+/-19% versus 41+/-10% and 100+/-8% versus 61+/-9% for atrial natriuretic factor and myosin light chain 2 in SHR-Cs and SHR-Es, respectively). The expression of sarcoplasmic reticulum Ca(2+) pump was significantly augmented, whereas that of Na(+)/Ca(2+) exchanger was unchanged (93+/-7% versus 167+/-8% and 158+/-13% versus 157+/-7%, sarcoplasmic reticulum Ca(2+) pump and Na(+)/Ca(2+) exchanger in SHR-Cs and SHR-Es, respectively; P<0.05). Endurance training inhibited apoptosis, as reflected by a decrease in caspase 3 activation and poly(ADP-ribose) polymerase-1 cleavage, and normalized calcineurin activity without inducing significant changes in the phosphatidylinositol 3-kinase/Akt pathway. The swimming routine improved midventricular shortening determined by echocardiography (32.4+/-0.9% versus 36.9+/-1.1% in SHR-Cs and SHR-Es, respectively; P<0.05) and decreased the left ventricular free wall thickness/left ventricular cavity radius toward an eccentric model of cardiac hypertrophy (0.59+/-0.02 versus 0.53+/-0.01 in SHR-Cs and SHR-Es, respectively; P<0.05). In conclusion, we present data demonstrating the effectiveness of endurance training to convert pathological into physiological hypertrophy improving cardiac performance. The reduction of myocardial fibrosis and calcineurin activity plus the increase in capillary density represent factors to be considered in determining this beneficial effect.

99 citations

Journal ArticleDOI
TL;DR: In this article, the authors quantify soil mechanical behavior related to compaction from farm machinery traffic on Typic Argiudoll under wheat (Triticum aestvium L. Merr.), soybean ( Glycine max L.Merr.) rotation in the northeastern Rolling Pampa region at Argentina, including five different traffic frequencies (0, 6, 8, 10 and 12 passes of a two wheel-drive, 52kW tractor running repeatedly on the same track).
Abstract: Direct seeding production in Argentina requires frequent traffic with farm machinery, in example 6–12 passes. The initially high level of soil compaction in some no till systems might suggest that the impact of subsequent traffic would be minimal, but data have not be consistent. Our objective was to quantify soil mechanical behavior related to compaction from farm machinery traffic on Typic Argiudoll under wheat ( Triticum aestvium L. Merr.), soybean ( Glycine max L. Merr.) rotation in the northeastern Rolling Pampa region at Argentina. Treatments included five different traffic frequencies (0, 6, 8, 10 and 12 passes of a two wheel-drive, 52 kW tractor running repeatedly on the same track). Total weight of the tractor was 3.1 Mg, with 1.0 and 2.1 Mg on the front and rear axles using 7.50 × 16 and 18.4 × 34 tyres, respectively. The speed of tractor traffic was 5.5 km h −1 . Variables measured were: (1) soil bulk density, (2) cone index in the 0–600 mm depth profile and (3) rut depth. Only 10 and 12 tractor passes produced significant increases in cone index and dry bulk density throughout the soil profile. Dry bulk density and cone index increased with number of passes. All frequencies compacted the top soil generating physical soil conditions that would be unsuitable for seedling emergence. Although soil had high bulk density prior to traffic treatments, a significant increment of compaction still occurred due to the high traffic frequencies applied.

99 citations

Journal ArticleDOI
TL;DR: A straightforward workflow combining homology search in Rhodnius prolixus genome sequence with cloning by rapid amplification of cDNA ends and mass spectrometry is shown to achieve the first comprehensive genomic, transcriptomic and neuropeptidomic analysis of an insect disease vector.
Abstract: We show a straightforward workflow combining homology search in Rhodnius prolixus genome sequence with cloning by rapid amplification of cDNA ends and mass spectrometry. We have identified 32 genes and their transcripts that encode a number of neuropeptide precursors leading to 194 putative peptides. We validated by mass spectrometry 82 of those predicted neuropeptides in the brain of R. prolixus to achieve the first comprehensive genomic, transcriptomic and neuropeptidomic analysis of an insect disease vector. Comparisons of available insect neuropeptide sequences revealed that the R. prolixus genome contains most of the conserved neuropeptides in insects, many of them displaying specific features at the sequence level. Some gene families reported here are identified for the first time in the order Hemiptera, a highly biodiverse group of insects that includes many human, animal and plant disease agents.

99 citations

Journal ArticleDOI
TL;DR: In this paper, the degree of protein denaturation, surface hydrophobicity and sulfhydryl groups were correlated with the water absorbing capacity of commercial soy protein isolates.
Abstract: Solubility and water absorbing capacity of commercial soy protein isolates were correlated with structural parameters. The physico-chemical properties studied were degree of protein denaturation, surface hydrophobicity and sulfhydryl groups. The results indicated that solubility and water absorption were affected differently as the parameters were varied. These functional properties depended on more than one structural parameter. Solubility in 0.2M NaCl solution provided information about the degree of denaturation of soybean protein isolates. Isolates with highly denatured proteins, high surface hydrophobicity, low solubility in 0.2M NaCl solution and low SH exhibited the highest water absorbing capacity.

99 citations


Authors

Showing all 13198 results

NameH-indexPapersCitations
David Cameron1541586126067
Subir Sarkar1491542144614
Mayda Velasco137130987579
Diego F. Torres13794872180
Heidi Sandaker12899976517
Vincent Garonne12892176980
Farid Ould-Saada12893176394
Ole Røhne128103875752
Peter Hansen128127186210
Maria-Teresa Dova12777873558
Vladimir Sulin12788475329
Andrei Snesarev12787574907
James Catmore12789275086
Ruslan Mashinistov12686073897
Fernando Monticelli12684373385
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202333
2022315
20211,491
20201,738
20191,675
20181,527