Institution
Netherlands Institute for Neuroscience
Facility•Amsterdam, Netherlands•
About: Netherlands Institute for Neuroscience is a facility organization based out in Amsterdam, Netherlands. It is known for research contribution in the topics: Population & Visual cortex. The organization has 716 authors who have published 1195 publications receiving 56185 citations.
Papers published on a yearly basis
Papers
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TL;DR: In this article, the prevalence and distribution of age-related macular degeneration (AMD) in the United States by age, race/ethnicity, and gender was estimated.
Abstract: Objective: To estimate the prevalence and distribution of age-related macular degeneration (AMD) in the United States by age, race/ethnicity, and gender.Methods: Summary prevalence estimates of drusen 125 pin or larger, neovascular AMD, and geographic atrophy were prepared separately for black and white persons in 5-year age intervals starting at 40 years. The estimated rates were based on a meta-analysis of recent population-based studies in the United States, Australia, and Europe. These rates were applied to 2000 US Census data and to projected US population figures for 2020 to estimate the number of the US population with drusen and AMD.Results: The overall prevalence of neovascular AMD and/or geographic atrophy in the US population 40 years and older is estimated to be 1.47% (95% confidence interval, 1.38%-1.55%), with 1.75 million citizens having AMD. The prevalence of AMD increased dramatically with age, with more than 15% of the white women older than 80 years having neovascular AMD and/or geographic atrophy. More than 7 million individuals had drusen measuring 125 pin or larger and were, therefore, at substantial risk of developing AMD. Owing to the rapidly aging population, the number of persons having AMD will increase by 50% to 2.95 million in 2020. Age-related macular degeneration was far more prevalent among white than among black persons.Conclusion: Age-related macular degeneration affects more than 1.75 million individuals in the United States. Owing to the rapid aging of the US population, this number will increase to almost 3 million by 2020.
2,389 citations
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New York University1, Nathan Kline Institute for Psychiatric Research2, MIND Institute3, Katholieke Universiteit Leuven4, University of Utah5, Yale University6, University of California, Los Angeles7, Massachusetts Institute of Technology8, Trinity College, Dublin9, Carnegie Mellon University10, Ben-Gurion University of the Negev11, Ludwig Maximilian University of Munich12, Oregon Health & Science University13, California Institute of Technology14, Indiana University15, San Diego State University16, University of Groningen17, Netherlands Institute for Neuroscience18, University of Wisconsin-Madison19, Cornell University20, University of Pittsburgh21, Stanford University22, University of Michigan23, Kennedy Krieger Institute24, Johns Hopkins University25
TL;DR: W Whole-brain analyses reconciled seemingly disparate themes of both hypo- and hyperconnectivity in the ASD literature; both were detected, although hypoconnectivity dominated, particularly for corticocortical and interhemispheric functional connectivity.
Abstract: Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and neuroscience because of their high prevalence, lifelong nature, complexity and substantial heterogeneity. Facing these obstacles requires large-scale multidisciplinary efforts. Although the field of genetics has pioneered data sharing for these reasons, neuroimaging had not kept pace. In response, we introduce the Autism Brain Imaging Data Exchange (ABIDE)-a grassroots consortium aggregating and openly sharing 1112 existing resting-state functional magnetic resonance imaging (R-fMRI) data sets with corresponding structural MRI and phenotypic information from 539 individuals with ASDs and 573 age-matched typical controls (TCs; 7-64 years) (http://fcon_1000.projects.nitrc.org/indi/abide/). Here, we present this resource and demonstrate its suitability for advancing knowledge of ASD neurobiology based on analyses of 360 male subjects with ASDs and 403 male age-matched TCs. We focused on whole-brain intrinsic functional connectivity and also survey a range of voxel-wise measures of intrinsic functional brain architecture. Whole-brain analyses reconciled seemingly disparate themes of both hypo- and hyperconnectivity in the ASD literature; both were detected, although hypoconnectivity dominated, particularly for corticocortical and interhemispheric functional connectivity. Exploratory analyses using an array of regional metrics of intrinsic brain function converged on common loci of dysfunction in ASDs (mid- and posterior insula and posterior cingulate cortex), and highlighted less commonly explored regions such as the thalamus. The survey of the ABIDE R-fMRI data sets provides unprecedented demonstrations of both replication and novel discovery. By pooling multiple international data sets, ABIDE is expected to accelerate the pace of discovery setting the stage for the next generation of ASD studies.
1,939 citations
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TL;DR: Sleep durations of ≤5 hours per night were associated with a significantly increased risk of hypertension in subjects between the ages of 32 and 59 years, and controlling for the potential confounding variables only partially attenuated this relationship.
Abstract: Depriving healthy subjects of sleep has been shown to acutely increase blood pressure and sympathetic nervous system activity. Prolonged short sleep durations could lead to hypertension through ext...
1,149 citations
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TL;DR: Evidence is reviewed showing that the expression of salience is remarkably similar across structures, remarkably different across tasks, and modified in important ways when the salient object is consistent with the goals of the participant.
818 citations
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TL;DR: It is argued that in many cases the neural processes in one brain are coupled to the neural Processes in another brain via the transmission of a signal through the environment, leading to complex joint behaviors that could not have emerged in isolation.
769 citations
Authors
Showing all 720 results
Name | H-index | Papers | Citations |
---|---|---|---|
Dick F. Swaab | 109 | 699 | 45574 |
Rainer Goebel | 99 | 443 | 33506 |
Eleonora Aronica | 91 | 521 | 29452 |
Ruud M. Buijs | 87 | 228 | 23662 |
Caroline C W Klaver | 79 | 352 | 28651 |
Chris I. De Zeeuw | 75 | 295 | 17288 |
Andries Kalsbeek | 74 | 294 | 16894 |
August B. Smit | 73 | 368 | 21451 |
Douglas P. Munoz | 72 | 245 | 21552 |
Henk J. Groenewegen | 72 | 161 | 24684 |
Johannes R. Vingerling | 71 | 182 | 18759 |
Rivka Ravid | 71 | 184 | 17038 |
Paulus T. V. M. de Jong | 69 | 168 | 16789 |
Andrew J. Lotery | 64 | 358 | 16739 |
Pieter R. Roelfsema | 64 | 257 | 18759 |