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Institution

North Carolina State University

EducationRaleigh, North Carolina, United States
About: North Carolina State University is a education organization based out in Raleigh, North Carolina, United States. It is known for research contribution in the topics: Population & Thin film. The organization has 44161 authors who have published 101744 publications receiving 3456774 citations. The organization is also known as: NCSU & North Carolina State University at Raleigh.
Topics: Population, Thin film, Silicon, Gene, Poison control


Papers
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Journal ArticleDOI
TL;DR: Analysis of patterns of local and genome-wide LD in 102 maize inbred lines representing much of the worldwide genetic diversity used in maize breeding suggests that association studies show great promise for identifying the genetic basis of important traits in maize with very high resolution.
Abstract: Association studies based on linkage disequilibrium (LD) can provide high resolution for identifying genes that may contribute to phenotypic variation. We report patterns of local and genome-wide LD in 102 maize inbred lines representing much of the worldwide genetic diversity used in maize breeding, and address its implications for association studies in maize. In a survey of six genes, we found that intragenic LD generally declined rapidly with distance (r2 < 0.1 within 1500 bp), but rates of decline were highly variable among genes. This rapid decline probably reflects large effective population sizes in maize during its evolution and high levels of recombination within genes. A set of 47 simple sequence repeat (SSR) loci showed stronger evidence of genome-wide LD than did single-nucleotide polymorphisms (SNPs) in candidate genes. LD was greatly reduced but not eliminated by grouping lines into three empirically determined subpopulations. SSR data also supplied evidence that divergent artificial selection on flowering time may have played a role in generating population structure. Provided the effects of population structure are effectively controlled, this research suggests that association studies show great promise for identifying the genetic basis of important traits in maize with very high resolution.

1,078 citations

Journal ArticleDOI
TL;DR: In this article, the recent developments and the characteristics of membrane separators for rechargeable lithium-ion batteries are reviewed and the outlook and future directions in this research field are also given.
Abstract: In this paper, the recent developments and the characteristics of membrane separators for lithium-ion batteries are reviewed. In recent years, there have been intensive efforts to develop advanced battery separators for rechargeable lithium-ion batteries for different applications such as portable electronics, electric vehicles, and energy storage for power grids. The separator is a critical component of lithium-ion batteries since it provides a physical barrier between the positive and negative electrodes in order to prevent electrical short circuits. The separator also serves as the electrolyte reservoir for the transport of ions during the charging and discharging cycles of a battery. The performance of lithium-ion batteries is greatly affected by the materials and structure of the separators. This paper introduces the requirements of battery separators and the structure and properties of five important types of membrane separators which are microporous membranes, modified microporous membranes, non-woven mats, composite membranes and electrolyte membranes. Each separator type has inherent advantages and disadvantages which influence the performance of lithium-ion batteries. The structures, characteristics, manufacturing, modification, and performance of separators are described in this review paper. The outlook and future directions in this research field are also given.

1,077 citations

Journal ArticleDOI
TL;DR: In this paper, statistical methods to account for population structure were extended for use with quantitative variation and applied to their evaluation of maize flowering time, which indicated that a suite of polymorphisms associated with differences in flowering time.
Abstract: Historically, association tests have been used extensively in medical genetics, but have had virtually no application in plant genetics. One obstacle to their application is the structured populations often found in crop plants, which may lead to nonfunctional, spurious associations. In this study, statistical methods to account for population structure were extended for use with quantitative variation and applied to our evaluation of maize flowering time. Mutagenesis and quantitative trait locus (QTL) studies suggested that the maize gene Dwarf8 might affect the quantitative variation of maize flowering time and plant height. The wheat orthologs of this gene contributed to the increased yields seen in the 'Green Revolution' varieties. We used association approaches to evaluate Dwarf8 sequence polymorphisms from 92 maize inbred lines. Population structure was estimated using a Bayesian analysis of 141 simple sequence repeat (SSR) loci. Our results indicate that a suite of polymorphisms associate with differences in flowering time, which include a deletion that may alter a key domain in the coding region. The distribution of nonsynonymous polymorphisms suggests that Dwarf8 has been a target of selection.

1,074 citations

Journal ArticleDOI
TL;DR: The authors show that regime switching is easily confused with long memory, even asymptotically, so long as only a small amount of regime switching occurs, in a sense that they make precise.

1,067 citations

Journal ArticleDOI
TL;DR: This article gives specific steps on how to create a codebook for coding interview data and how to train others to code using the codebook, including how to establish reliability.
Abstract: This article gives specific steps on how to create a codebook for coding interview data. The authors examine the development of theory- and data-driven codes through the discussion of a professiona...

1,066 citations


Authors

Showing all 44525 results

NameH-indexPapersCitations
Yi Cui2201015199725
Jing Wang1844046202769
Rodney S. Ruoff164666194902
Carlos Bustamante161770106053
David W. Johnson1602714140778
Joseph Wang158128298799
David Tilman158340149473
Jay Hauser1552145132683
James M. Tour14385991364
Joseph T. Hupp14173182647
Bin Liu138218187085
Rudolph E. Tanzi13563885376
Richard C. Boucher12949054509
David B. Allison12983669697
Robert W. Heath128104973171
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023160
2022652
20215,262
20205,458
20194,888
20184,522