Northampton Community College

About: Northampton Community College is a education organization based out in Bethlehem, Pennsylvania, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 3410 authors who have published 4582 publications receiving 130398 citations. The organization is also known as: Northampton County Area Community College.

A Focused Systematic Review of Pharmacological Treatment for Borderline Personality Disorder.

Abstract: Medicines are routinely prescribed to treat borderline personality disorder (BPD) despite a relative lack of high-quality evidence and in breach of some treatment guidelines. An earlier Cochrane review of pharmacotherapy in BPD underlined the lack of evidence, encouraged the replication of earlier studies, but also emphasised the pressing need for more randomised placebo-controlled trials, and for those studies to employ broadened inclusion criteria. The authors searched bibliographic databases, reference lists of articles and trials registers. Records were screened to identify those that met the inclusion criteria. Full-text articles were screened and assessed for eligibility. On-going trials of pharmacotherapy in BPD were also identified. Fifteen new studies of pharmacotherapy for BPD were identified since the earlier review. Eight of those examined second generation antipsychotics, two investigated mood stabilisers, three investigated antidepressants and two studied the effectiveness of opioid antagonists. Results for the effectiveness of antipsychotics appeared to be mixed. There has been little recent evidence to support the use of mood stabilisers. There is a lack of new placebo-controlled, randomised controlled trials investigating antidepressants and limited new evidence to support the use of opioid antagonists. The review revealed that there remains a dearth of high-quality research evidence to help patients, carers and clinicians make sound and safe evidence-based decisions about medicines to treat BPD.

Absolute amount of ribonucleic acid in viruses.

Abstract: ON the basis of work with plant virus strains, Knight1 expressed the view that all strains of virus contain the same quantity of nucleic acid. Recent experiments have shown that there exist a number of animal viruses which contain only ribonucleic acid. If one plots the percentage of ribonucleic acid against the particle weight of viruses containing ribonucleic acid, a hyperbola results. Thus in animal viruses also the absolute amount of ribonucleic acid seems to be the same, and coincides with the quantity found in most plant viruses. As the actual equation of the hyperbola is percentage ribonucleic acid × molecular weight of the virus = 2 × 108, the average weight of the ribonucleic acid in a single virus particle amounts roughly to two million times that of a hydrogen atom.

The natural fluorescence of wool

Abstract: Wool may be excited by both mid-and near-u.v. radiation, emitting fluorescence. The extent of visible fluorescence depends on the origin of the wool and the degree of weathering, (the tips of the fibres being more fluorescent than the roots) and chemical modification. In particular oxidative treatments such as chlorination of shrink-resist procedures or peroxide bleaching processes increase the intensity of visible fluorescence but decrease the intensity of u.v. fluorescence (emission maximum at about 350 nm). It is proposed that the presence of these fluorescent chromophores in the fibre relates to the susceptibility of wool to yellow on exposure to light.