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Institution

Northampton Community College

EducationBethlehem, Pennsylvania, United States
About: Northampton Community College is a education organization based out in Bethlehem, Pennsylvania, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 3410 authors who have published 4582 publications receiving 130398 citations. The organization is also known as: Northampton County Area Community College.


Papers
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Journal ArticleDOI
TL;DR: The use of photographs in geomorphology has been for interpretation, but developments in photogrammetry may allow the full advantages of the photograph as a means of acquiring and storing quantitative information to be used.
Abstract: Current emphasis in geomorphology recognizes the need for the accurate representation of topographic form, reflected in the growth of digital terrain and elevation modelling. A key requirement of such strategies is the efficient acquisition of information in an appropriate form and at an appropriate resolution to the landform under consideration. The traditional use of photographs in geomorphology has been for interpretation, but developments in photogrammetry may allow the full advantages of the photograph as a means of acquiring and storing quantitative information to be used. The photograph can provide information on all areas visible on a photograph; the information is acquired retrodictively; the photograph preserves the spatial relationship of morphological units; the collection of photographs requires minimal landform contact; the photograph records extra explanatory information; and photographs can be obtained at an appropriate temporal resolution to the landform under investigation. However, opti...

81 citations

Journal ArticleDOI
TL;DR: This review has summarised the major techniques for testing these characteristics and the mechanisms involved in the variety of cross-linking reactions to achieve particular properties of collagen.
Abstract: Collagen is the most abundant protein in animals and because of its high mechanical strength and good resistance to degradation has been utilized in a wide range of products in industry whilst its low antigenicity has resulted in its widespread use in medicine Collagen products can be purified from fibres, molecules reconstituted as fibres or from specific recombinant polypeptides with preferred properties A common feature of all these biomaterials is the need for stable chemical cross-linking to control the mechanical properties and the residence time in the body, and to some extent the immunogenicity of the device This can be achieved by a number of different cross-linking agents that react with specific amino acid residues on the collagen molecule imparting individual biochemical, thermal and mechanical characteristics to the biomaterial In this review we have summarised the major techniques for testing these characteristics and the mechanisms involved in the variety of cross-linking reactions to achieve particular properties

81 citations

Journal ArticleDOI
TL;DR: In this paper, the blocks of the Brauer algebra were determined in characteristic zero and information on the submodule structure of standard modules for this algebra was given, as well as a characterization of the sub-module structure.
Abstract: We determine the blocks of the Brauer algebra in characteristic zero. We also give information on the submodule structure of standard modules for this algebra.

81 citations

Journal ArticleDOI
TL;DR: A survey was made of the work and hobbies of patients with the carpal tunnel syndrome and it was suggested that this type of manual activity can be a causal factor in the development of the, so-called, 'spontaneous' carpal Tunnel syndrome.
Abstract: A survey was made of the work and hobbies of 658 patients with the carpal tunnel syndrome. Seventy-nine per cent of the patients were employed in work requiring light, highly repetitive movements of the wrists and fingers. Fifty-one per cent of the unemployed housewives knitted. It is suggested that this type of manual activity can be a causal factor in the development of the, so-called, 'spontaneous' carpal tunnel syndrome.

81 citations

Journal ArticleDOI
TL;DR: A new ultrasensitive differential scanning calorimeter (DSC) instrument is described, which utilizes autosampling for continuous operation and method for measuring binding constants can be extended to ultratight interactions involving either ligand-protein or protein-protein binding.
Abstract: A new ultrasensitive differential scanning calorimeter (DSC) instrument is described, which utilizes autosampling for continuous operation. High scanning rates to 250 deg/h with rapid cooling and equilibration between scans facilitates higher sample throughput up to 50 samples during each 24 h of unattended operation. The instrument is suited for those pharmaceutical applications where higher throughput is important, such as screening drug candidates for binding constant or screening solution conditions for stability of liquid protein formulations. Results are presented on the binding of five different anionic inhibitors to ribonuclease A, which included cytidine 2'-monophosphate (2'CMP), 3'CMP, uridine 3'-monophosphate, pyrophosphate, and phosphate. Binding constants K(B) (or dissociation constants K(d)) are obtained from the shift in the transition temperature T(M) for ribonuclease thermal unfolding in the presence of ligand relative to the transition temperature in the absence of ligand. Measured binding constants ranged from 155 M(-1) (K(d) = 6.45 mM) for the weak-binding phosphate anion to 13100 M(-1) (K(d) = 76.3 microM) for the strongest binding ligand, 2'CMP. The DSC method for measuring binding constants can also be extended to ultratight interactions involving either ligand-protein or protein-protein binding.

81 citations


Authors

Showing all 3411 results

NameH-indexPapersCitations
Simon Baron-Cohen172773118071
Pete Smith1562464138819
Martin N. Rossor12867095743
Mark D. Griffiths124123861335
Richard G. Brown8321726205
Brendon Stubbs8175428180
Stuart N. Lane7633715788
Paul W. Burgess6915621038
Thomas Dietz6820337313
Huseyin Sehitoglu6732414378
Susan Golombok6721512856
David S.G. Thomas6322814796
Stephen Morris6344316484
Stephen Robertson6119723363
Michael J. Morgan6026612211
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20233
20221
202182
202073
201968
201865