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Institution

Northwestern University

EducationEvanston, Illinois, United States
About: Northwestern University is a education organization based out in Evanston, Illinois, United States. It is known for research contribution in the topics: Population & Transplantation. The organization has 75430 authors who have published 188857 publications receiving 9463252 citations. The organization is also known as: Northwestern & NU.


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Journal ArticleDOI
TL;DR: Cross-sectional and growth curve analyses indicate that aging is associated with more positive overall emotional well-being, with greater emotional stability and with more complexity (as evidenced by greater co-occurrence of positive and negative emotions).
Abstract: Recent evidence suggests that emotional well-being improves from early adulthood to old age. This study used experience-sampling to examine the developmental course of emotional experience in a representative sample of adults spanning early to very late adulthood. Participants (N = 184, Wave 1; N = 191, Wave 2; N = 178, Wave 3) reported their emotional states at five randomly selected times each day for a one week period. Using a measurement burst design, the one-week sampling procedure was repeated five and then ten years later. Cross-sectional and growth curve analyses indicate that aging is associated with more positive overall emotional well-being, with greater emotional stability and with more complexity (as evidenced by greater co-occurrence of positive and negative emotions). These findings remained robust after accounting for other variables that may be related to emotional experience (personality, verbal fluency, physical health, and demographic variables). Finally, emotional experience predicted mortality; controlling for age, sex, and ethnicity, individuals who experienced relatively more positive than negative emotions in everyday life were more likely to have survived over a 13 year period. Findings are discussed in the theoretical context of socioemotional selectivity theory.

965 citations

Journal ArticleDOI
TL;DR: In this paper, the authors discuss the importance of background knowledge in a psycholinguistic model of EFL/ESL reading and demonstrate the relevance of schema-theoretic views of reading to teaching reading to English learners.
Abstract: This article discusses the important role of background knowledge in a psycholinguistic model of EFL/ESL reading and demonstrates the relevance of schema-theoretic views of reading to the teaching of reading to EFL/ESL students. According to schema theory, reading comprehension is an interactive process between the text and the reader's prior background knowledge (Adams and Collins 1979, Rumelhart 1980). Reading comprehension involves one's knowledge of the world, which may be culturally based and culturally biased. Classroom implications of the schema-theoretic view of reading for EFL/ESL reading pedagogy are discussed, with techniques suggested for bringing about reader-centered EFL/ESL reading.

965 citations

Journal ArticleDOI
TL;DR: In this article, single-walled carbon nanotubes (SWCNTs) were functionalized with amino groups via chemical modification of carboxyl groups introduced on the carbon nanotide surface.
Abstract: Single-walled carbon nanotubes (SWCNT) functionalized with amino groups were prepared via chemical modification of carboxyl groups introduced on the carbon nanotube surface. Two different approaches (amide and amine-moieties) were used to produce the amino-functionalized nanotubes. The amino-termination allows further chemistry of the functionalized SWCNTs and makes possible covalent bonding to polymers and biological systems such as DNA and carbohydrates. The functionalization of the SWCNTs was characterized in detail using FTIR and XPS.

965 citations

Journal ArticleDOI
Ali H. Mokdad1, Katherine Ballestros1, Michelle Echko1, Scott D Glenn1, Helen E Olsen1, Erin C Mullany1, Alexander Lee1, Abdur Rahman Khan2, Alireza Ahmadi3, Alireza Ahmadi4, Alize J. Ferrari5, Alize J. Ferrari6, Alize J. Ferrari1, Amir Kasaeian7, Andrea Werdecker, Austin Carter1, Ben Zipkin1, Benn Sartorius8, Benn Sartorius9, Berrin Serdar10, Bryan L. Sykes11, Christopher Troeger1, Christina Fitzmaurice1, Christina Fitzmaurice12, Colin D. Rehm13, Damian Santomauro1, Damian Santomauro6, Damian Santomauro5, Daniel Kim14, Danny V. Colombara1, David C. Schwebel15, Derrick Tsoi1, Dhaval Kolte16, Elaine O. Nsoesie1, Emma Nichols1, Eyal Oren17, Fiona J Charlson6, Fiona J Charlson1, Fiona J Charlson5, George C Patton18, Gregory A. Roth1, H. Dean Hosgood19, Harvey Whiteford1, Harvey Whiteford6, Harvey Whiteford5, Hmwe H Kyu1, Holly E. Erskine1, Holly E. Erskine5, Holly E. Erskine6, Hsiang Huang20, Ira Martopullo1, Jasvinder A. Singh15, Jean B. Nachega21, Jean B. Nachega22, Jean B. Nachega23, Juan Sanabria24, Juan Sanabria25, Kaja Abbas26, Kanyin Ong1, Karen M. Tabb27, Kristopher J. Krohn1, Leslie Cornaby1, Louisa Degenhardt1, Louisa Degenhardt28, Mark Moses1, Maryam S. Farvid29, Max Griswold1, Michael H. Criqui30, Michelle L. Bell31, Minh Nguyen1, Mitch T Wallin32, Mitch T Wallin33, Mojde Mirarefin1, Mostafa Qorbani, Mustafa Z. Younis34, Nancy Fullman1, Patrick Liu1, Paul S Briant1, Philimon Gona35, Rasmus Havmoller3, Ricky Leung36, Ruth W Kimokoti37, Shahrzad Bazargan-Hejazi38, Shahrzad Bazargan-Hejazi39, Simon I. Hay1, Simon I. Hay40, Simon Yadgir1, Stan Biryukov1, Stein Emil Vollset1, Stein Emil Vollset41, Tahiya Alam1, Tahvi Frank1, Talha Farid2, Ted R. Miller42, Ted R. Miller43, Theo Vos1, Till Bärnighausen29, Till Bärnighausen44, Tsegaye Telwelde Gebrehiwot45, Yuichiro Yano46, Ziyad Al-Aly47, Alem Mehari48, Alexis J. Handal49, Amit Kandel50, Ben Anderson51, Brian J. Biroscak52, Brian J. Biroscak31, Dariush Mozaffarian53, E. Ray Dorsey54, Eric L. Ding29, Eun-Kee Park55, Gregory R. Wagner29, Guoqing Hu56, Honglei Chen57, Jacob E. Sunshine51, Jagdish Khubchandani58, Janet L Leasher59, Janni Leung5, Janni Leung51, Joshua A. Salomon29, Jürgen Unützer51, Leah E. Cahill60, Leah E. Cahill29, Leslie T. Cooper61, Masako Horino, Michael Brauer1, Michael Brauer62, Nicholas J K Breitborde63, Peter J. Hotez64, Roman Topor-Madry65, Roman Topor-Madry66, Samir Soneji67, Saverio Stranges68, Spencer L. James1, Stephen M. Amrock69, Sudha Jayaraman70, Tejas V. Patel, Tomi Akinyemiju15, Vegard Skirbekk41, Vegard Skirbekk71, Yohannes Kinfu72, Zulfiqar A Bhutta73, Jost B. Jonas44, Christopher J L Murray1 
Institute for Health Metrics and Evaluation1, University of Louisville2, Karolinska Institutet3, Kermanshah University of Medical Sciences4, University of Queensland5, Centre for Mental Health6, Tehran University of Medical Sciences7, South African Medical Research Council8, University of KwaZulu-Natal9, University of Colorado Boulder10, University of California, Irvine11, Fred Hutchinson Cancer Research Center12, Montefiore Medical Center13, Northeastern University14, University of Alabama at Birmingham15, Brown University16, San Diego State University17, University of Melbourne18, Albert Einstein College of Medicine19, Cambridge Health Alliance20, University of Cape Town21, Johns Hopkins University22, University of Pittsburgh23, Case Western Reserve University24, Marshall University25, University of London26, University of Illinois at Urbana–Champaign27, National Drug and Alcohol Research Centre28, Harvard University29, University of California, San Diego30, Yale University31, Veterans Health Administration32, Georgetown University33, Jackson State University34, University of Massachusetts Boston35, State University of New York System36, Simmons College37, Charles R. Drew University of Medicine and Science38, University of California, Los Angeles39, University of Oxford40, Norwegian Institute of Public Health41, Curtin University42, Pacific Institute43, Heidelberg University44, Jimma University45, Northwestern University46, Washington University in St. Louis47, Howard University48, University of New Mexico49, University at Buffalo50, University of Washington51, University of South Florida52, Tufts University53, University of Rochester Medical Center54, Kosin University55, Central South University56, Michigan State University57, Ball State University58, Nova Southeastern University59, Dalhousie University60, Mayo Clinic61, University of British Columbia62, Ohio State University63, Baylor University64, Wrocław Medical University65, Jagiellonian University Medical College66, Dartmouth College67, University of Western Ontario68, Oregon Health & Science University69, Virginia Commonwealth University70, Columbia University71, University of Canberra72, Aga Khan University73
10 Apr 2018-JAMA
TL;DR: There are wide differences in the burden of disease at the state level and specific diseases and risk factors, such as drug use disorders, high BMI, poor diet, high fasting plasma glucose level, and alcohol use disorders are increasing and warrant increased attention.
Abstract: Introduction Several studies have measured health outcomes in the United States, but none have provided a comprehensive assessment of patterns of health by state. Objective To use the results of the Global Burden of Disease Study (GBD) to report trends in the burden of diseases, injuries, and risk factors at the state level from 1990 to 2016. Design and Setting A systematic analysis of published studies and available data sources estimates the burden of disease by age, sex, geography, and year. Main Outcomes and Measures Prevalence, incidence, mortality, life expectancy, healthy life expectancy (HALE), years of life lost (YLLs) due to premature mortality, years lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 333 causes and 84 risk factors with 95% uncertainty intervals (UIs) were computed. Results Between 1990 and 2016, overall death rates in the United States declined from 745.2 (95% UI, 740.6 to 749.8) per 100 000 persons to 578.0 (95% UI, 569.4 to 587.1) per 100 000 persons. The probability of death among adults aged 20 to 55 years declined in 31 states and Washington, DC from 1990 to 2016. In 2016, Hawaii had the highest life expectancy at birth (81.3 years) and Mississippi had the lowest (74.7 years), a 6.6-year difference. Minnesota had the highest HALE at birth (70.3 years), and West Virginia had the lowest (63.8 years), a 6.5-year difference. The leading causes of DALYs in the United States for 1990 and 2016 were ischemic heart disease and lung cancer, while the third leading cause in 1990 was low back pain, and the third leading cause in 2016 was chronic obstructive pulmonary disease. Opioid use disorders moved from the 11th leading cause of DALYs in 1990 to the 7th leading cause in 2016, representing a 74.5% (95% UI, 42.8% to 93.9%) change. In 2016, each of the following 6 risks individually accounted for more than 5% of risk-attributable DALYs: tobacco consumption, high body mass index (BMI), poor diet, alcohol and drug use, high fasting plasma glucose, and high blood pressure. Across all US states, the top risk factors in terms of attributable DALYs were due to 1 of the 3 following causes: tobacco consumption (32 states), high BMI (10 states), or alcohol and drug use (8 states). Conclusions and Relevance There are wide differences in the burden of disease at the state level. Specific diseases and risk factors, such as drug use disorders, high BMI, poor diet, high fasting plasma glucose level, and alcohol use disorders are increasing and warrant increased attention. These data can be used to inform national health priorities for research, clinical care, and policy.

962 citations

Journal ArticleDOI
TL;DR: Although the CIPN trials are inconclusive regarding tricyclic antidepressants (such as nortriptyline), gabapentin, and a compounded topical gel containing baclofen, amitriptylines HCL, and ketamine, these agents may be offered on the basis of data supporting their utility in other neuropathic pain conditions given the limited other CIPn treatment options.
Abstract: Purpose To provide evidence-based guidance on the optimum prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathies (CIPN) in adult cancer survivors. Methods A systematic literature search identified relevant, randomized controlled trials (RCTs) for the treatment of CIPN. Primary outcomes included incidence and severity of neuropathy as measured by neurophysiologic changes, patient-reported outcomes, and quality of life. Results A total of 48 RCTs met eligibility criteria and comprise the evidentiary basis for the recommendations. Trials tended to be small and heterogeneous, many with insufficient sample sizes to detect clinically important differences in outcomes. Primary outcomes varied across the trials, and in most cases, studies were not directly comparable because of different outcomes, measurements, and instruments used at different time points. The strength of the recommendations is based on the quality, amount, and consistency of the evidence and the ba...

962 citations


Authors

Showing all 76189 results

NameH-indexPapersCitations
George M. Whitesides2401739269833
Ralph B. D'Agostino2261287229636
Daniel Levy212933194778
David Miller2032573204840
Ronald M. Evans199708166722
Michael Marmot1931147170338
Robert C. Nichol187851162994
Scott M. Grundy187841231821
Stuart H. Orkin186715112182
Michael A. Strauss1851688208506
Ralph Weissleder1841160142508
Patrick O. Brown183755200985
Aaron R. Folsom1811118134044
Valentin Fuster1791462185164
Ronald C. Petersen1781091153067
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023275
20221,183
202110,513
202010,260
20199,331
20188,301