Institution
Nottingham Trent University
Education•Nottingham, United Kingdom•
About: Nottingham Trent University is a education organization based out in Nottingham, United Kingdom. It is known for research contribution in the topics: Population & Addiction. The organization has 4702 authors who have published 12862 publications receiving 307430 citations. The organization is also known as: NTU & Trent Polytechnic.
Papers published on a yearly basis
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Iowa State University1, Ohio Wesleyan University2, University of Geneva3, University of Rochester4, University of Toledo5, Brigham Young University6, Naval Medical Center San Diego7, University of Wisconsin-Madison8, Nottingham Trent University9, University of Connecticut10, Coventry University11, Center on Media and Child Health12, St. Bonaventure University13
TL;DR: IGD does, therefore, appear to be an area in which additional research is clearly needed, and several of the critical questions that future research should address are discussed and recommendations for clinicians, policy makers, and educators are provided on the basis of what the authors know at this time.
Abstract: The American Psychiatric Association recently included Internet gaming disorder (IGD) as a potential diagnosis, recommending that further study be conducted to help illuminate it more clearly. This paper is a summary of the review undertaken by the IGD Working Group as part of the 2015 National Academy of Sciences Sackler Colloquium on Digital Media and Developing Minds. By using measures based on or similar to the IGD definition, we found that prevalence rates range between ∼1% and 9%, depending on age, country, and other sample characteristics. The etiology of IGD is not well-understood at this time, although it appears that impulsiveness and high amounts of time gaming may be risk factors. Estimates for the length of time the disorder can last vary widely, but it is unclear why. Although the authors of several studies have demonstrated that IGD can be treated, no randomized controlled trials have yet been published, making any definitive statements about treatment impossible. IGD does, therefore, appear to be an area in which additional research is clearly needed. We discuss several of the critical questions that future research should address and provide recommendations for clinicians, policy makers, and educators on the basis of what we know at this time.
140 citations
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TL;DR: The research reported herein represents an important step toward the preparation of functional mesostructures with controlled helical architectures and shows the benefits of reducing the nonfunctional part of the molecule, in this case with short chiral isopentyl chains.
Abstract: The controlled preparation of chiral structures is a contemporary challenge for supramolecular science because of the interesting properties that can arise from the resulting materials, and here we show that a synthetic nonamphiphilic C3 compound containing π-functional tetrathiafulvalene units can form this kind of object. We describe the synthesis, characterization, and self-assembly properties in solution and in the solid state of the enantiopure materials. Circular dichroism (CD) measurements show optical activity resulting from the presence of twisted stacks of preferential helicity and also reveal the critical importance of fiber nucleation in their formation. Molecular mechanics (MM) and molecular dynamics (MD) simulations combined with CD theoretical calculations demonstrate that the (S) enantiomer provides the (M) helix, which is more stable than the (P) helix for this enantiomer. This relationship is for the first time established in this family of C3 symmetric compounds. In addition, we show th...
140 citations
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TL;DR: It is concluded that sudden isolated stabling is stressful to young and naive horses, resulting in a high prevalence of stereotypies and abnormal behaviours, and provided some support for the notion that social stress in horses may be associated with a blunted adrenocortical response to CRF challenge.
140 citations
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TL;DR: In this paper, the advantages, disadvantages and other implications of using the Internet to collect data from gaming addicts are discussed and reviewed, and some of the methodological and ethical issues associated with specific (rather then generic) online methodologies that have been used to carry out gaming addiction research are outlined.
Abstract: The paper outlines the advantages, disadvantages, and other implications of using the Internet to collect data from gaming addicts. Drawing from experience of numerous addiction studies carried out online by the author, and by reviewing the methodological literature examining online data collection among both gambling addicts and video game addicts, the main issues concerning data collected using the Internet are discussed and reviewed. This paper extends upon previous methodological papers in the area by outlining some of the methodological and ethical issues associated with specific (rather then generic) online methodologies that have been used to carry out gaming addiction research. The specific online data collection methods examined include the collection of gambling and video game addiction research data via (i) online questionnaires, (ii) online forums, (iii) online participant observation, (iv) online secondary data, (v) online interviews, (vi) online exemplar websites, and (vii) mixed methods online evaluation. It is concluded that the many advantages of online research methods can be a useful and practical way of examining many different aspects of gambling and video game addictions.
140 citations
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TL;DR: It is concluded that the function of the tomato APPR2-Like gene is conserved across taxa and that it encodes a protein that has an important role in ripening.
Abstract: Carotenoids represent some of the most important secondary metabolites in the human diet, and tomato (Solanum lycopersicum) is a rich source of these health-promoting compounds. In this work, a novel and fruit-related regulator of pigment accumulation in tomato has been identified by artificial neural network inference analysis and its function validated in transgenic plants. A tomato fruit gene regulatory network was generated using artificial neural network inference analysis and transcription factor gene expression profiles derived from fruits sampled at various points during development and ripening. One of the transcription factor gene expression profiles with a sequence related to an Arabidopsis (Arabidopsis thaliana) ARABIDOPSIS PSEUDO RESPONSE REGULATOR2-LIKE gene (APRR2-Like) was up-regulated at the breaker stage in wild-type tomato fruits and, when overexpressed in transgenic lines, increased plastid number, area, and pigment content, enhancing the levels of chlorophyll in immature unripe fruits and carotenoids in red ripe fruits. Analysis of the transcriptome of transgenic lines overexpressing the tomato APPR2-Like gene revealed up-regulation of several ripening-related genes in the overexpression lines, providing a link between the expression of this tomato gene and the ripening process. A putative ortholog of the tomato APPR2-Like gene in sweet pepper (Capsicum annuum) was associated with pigment accumulation in fruit tissues. We conclude that the function of this gene is conserved across taxa and that it encodes a protein that has an important role in ripening.
140 citations
Authors
Showing all 4806 results
Name | H-index | Papers | Citations |
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David L. Kaplan | 177 | 1944 | 146082 |
Paul Mitchell | 146 | 1378 | 95659 |
Matthew Nguyen | 131 | 1291 | 84346 |
Ian O. Ellis | 126 | 1051 | 75435 |
Mark D. Griffiths | 124 | 1238 | 61335 |
Tao Zhang | 123 | 2772 | 83866 |
Graham J. Hutchings | 97 | 995 | 44270 |
Andrzej Cichocki | 97 | 952 | 41471 |
Chris Ryan | 95 | 971 | 34388 |
Graham Pawelec | 89 | 572 | 27373 |
Christopher D. Buckley | 88 | 440 | 25664 |
Ester Cerin | 78 | 279 | 27086 |
Michael Hofreiter | 78 | 271 | 20628 |
Craig E. Banks | 77 | 569 | 27520 |
John R. Griffiths | 76 | 356 | 23179 |