Ocean University of China

About: Ocean University of China is a education organization based out in Qingdao, China. It is known for research contribution in the topics: Population & Sea surface temperature. The organization has 27604 authors who have published 27886 publications receiving 440181 citations. The organization is also known as: Zhōngguó Hǎiyáng Dàxué & OUC.

A κ-carrageenan derived oligosaccharide prepared by enzymatic degradation containing anti-tumor activity

Abstract: Depolymerization of κ-carrageenan was performed using carrageenase isolated from the cell-free medium of a culture of marine Cytophaga sp. MCA-2. The low-molecular-weight carrageenans after ultrafiltration and lyophilization were sulfonated with formamide-chlorosulfonic acid. The anti-tumor activity of the products with different molecular weight was determined by using Sarcoma 180 tumor in mouse. A carrageenan oligosaccharide with a molecular weight of 1726, administered orally at a dose of 100 mg kg−1 mouse markedly inhibited tumor formation. However, the anti-tumor activity of high-sulfonated carrageenan was much less than that of the non-sulfonated or light-sulfonated preparation. The activities of the latter products on superoxide dismutase and catalase were enhanced considerably, which suggests that carrageenan oligosaccharide was effective in promoting the antioxidation ability and eliminating danger from free radicals. The preparations showed special effects on immunological regulation, especially the phagocytosis ratio and phagocytosis index of macrophage, which might be beneficial for the anti-tumor activity. Although no anti-tumor activity of this product was detected in vitro, suggesting that its activity differs between in vitro and in vivo, this 1726 molecular weight product provides a potent clinical use in tumor treatment.

Seasonal Variations of Yellow Sea Fog: Observations and Mechanisms*

Abstract: Sea fog is frequently observed over the Yellow Sea, with an average of 50 fog days on the Chinese coast during April‐July. The Yellow Sea fog season is characterized by an abrupt onset in April in the southern coast of Shandong Peninsula and an abrupt, basin-wide termination in August. This study investigates the mechanisms for such steplike evolution that is inexplicable from the gradual change in solar radiation. From March to April over the northwestern Yellow Sea, a temperature inversion forms in a layer 100‐350 m above the sea surface, and the prevailing surface winds switch from northwesterly to southerly, both changes that are favorable for advection fog. The land‐sea contrast is the key to these changes. In April, the land warms up much faster than the ocean. The prevailing west-southwesterlies at 925 hPa advect warm continental air to form an inversion over the western Yellow Sea. The land‐sea differential warming also leads to the formation of a shallow anticyclone over the cool Yellow and northern East China Seas in April. The southerlies on the west flank of this anticyclone advect warm and humid air from the south, causing the abrupt fog onset on the Chinese coast. The lack of such warm/moist advection on the east flank of the anticyclone leads to a gradual increase in fog occurrence on the Korean coast. The retreat of Yellow Sea fog is associated with a shift in the prevailing winds from southerly to easterly from July to August. The August wind shift over the Yellow Sea is part of a large-scale change in the East Asian‐western Pacific monsoons, characterized by enhanced convection over the subtropical northwest Pacific and the resultant teleconnection into the midlatitudes, the