Ocean University of China

About: Ocean University of China is a education organization based out in Qingdao, China. It is known for research contribution in the topics: Population & Sea surface temperature. The organization has 27604 authors who have published 27886 publications receiving 440181 citations. The organization is also known as: Zhōngguó Hǎiyáng Dàxué & OUC.

MomL, a Novel Marine-Derived N-Acyl Homoserine Lactonase from Muricauda olearia

Abstract: Gram-negative bacteria use N-acyl homoserine lactones (AHLs) as quorum sensing (QS) signaling molecules for interspecies communication, and AHL-dependent QS is related with virulence factor production in many bacterial pathogens. Quorum quenching, the enzymatic degradation of the signaling molecule, would attenuate virulence rather than kill the pathogens, and thereby reduce the potential for evolution of drug resistance. In a previous study, we showed that Muricauda olearia Th120, belonging to the class Flavobacteriia, has strong AHL degradative activity. In this study, an AHL lactonase (designated MomL), which could degrade both short- and long-chain AHLs with or without a substitution of oxo-group at the C-3 position, was identified from Th120. Liquid chromatography-mass spectrometry analysis demonstrated that MomL functions as an AHL lactonase catalyzing AHL degradation through lactone hydrolysis. MomL is an AHL lactonase belonging to the metallo-β-lactamase superfamily that harbors an N-terminal signal peptide. The overall catalytic efficiency of MomL for C6-HSL is ∼2.9 × 105 s−1 M−1. Metal analysis and site-directed mutagenesis showed that, compared to AiiA, MomL has a different metal-binding capability and requires the histidine and aspartic acid residues for activity, while it shares the “HXHXDH” motif with other AHL lactonases belonging to the metallo-β-lactamase superfamily. This suggests that MomL is a representative of a novel type of secretory AHL lactonase. Furthermore, MomL significantly attenuated the virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans infection model, which suggests that MomL has the potential to be used as a therapeutic agent.

Late Paleozoic closure of the Ob-Zaisan Ocean along the Irtysh shear zone (NW China): Implications for arc amalgamation and oroclinal bending in the Central Asian orogenic belt

Abstract: The largest accretionary orogen in the world, the Central Asian orogenic belt, has evolved through the assembly of various oceanic and continental blocks. Understanding the processes associated with the development of this orogenic belt relies on precise recognition of the boundaries between various terranes. One such major suture zone, which records the collisional history of the Siberian marginal arc system (Chinese Altai) with intra-oceanic arc systems (East/West Junggar), is the Irtysh shear zone in NW China. The spatial continuity and the tectonic nature of this shear zone are still poorly understood, but its development has supposedly made a significant impact on the architecture of the western Central Asian orogenic belt and the formation of the Kazakhstan orocline. Here, we provide new insight into the evolution of this shear zone based on detrital zircon ages, Hf isotope composition, structural data and Ar/Ar age constraints on the timing of deformation. Our results show a major discrepancy in detrital zircon populations and Hf model ages across the southern Chinese Altai and the northern East/West Junggar, thus allowing us to map the exact location of the tectonic boundary. Detrital zircon data constrain the initial closure of the Ob-Zaisan Ocean to the late Carboniferous (<323 Ma), and new structural and Ar/Ar geochronological data shed light on the subsequent collisional processes. We propose that the collisional zone between the Chinese Altai and the East/West Junggar was initially subjected to crustal thickening at ca. 323-295 Ma, followed by orogen-parallel extension (ca. 295 Ma) and transpressional deformation (ca. 286-253 Ma). The closure of the Ob-Zaisan Ocean in NW China postdates the initial phase of oroclinal bending in the western Central Asian orogenic belt, thus indicating that oroclinal bending initiated during subduction. Based on our new constraints and other available geological data, we suggest that the early stage of oroclinal bending was likely driven by slab rollback.

Poleward Shift of the Major Ocean Gyres Detected in a Warming Climate

Abstract: Recent evidence shows that wind‐driven ocean currents, like the western boundary currents, are strongly affected by global warming. However, due to insufficient observations both on temporal and spatial scales, the impact of climate change on large‐scale ocean gyres is still not clear. Here, based on satellite observations of sea surface height and sea surface temperature, we find a consistent poleward shift of the major ocean gyres. Due to strong natural variability, most of the observed ocean gyre shifts are not statistically significant, implying that natural variations may contribute to the observed trends. However, climate model simulations forced with increasing greenhouse gases suggest that the observed shift is most likely to be a response of global warming. The displacement of ocean gyres, which is coupled with the poleward shift of extratropical atmospheric circulation, has broad impacts on ocean heat transport, regional sea level rise, and coastal ocean circulation.