Institution
Ocean University of China
Education•Qingdao, China•
About: Ocean University of China is a education organization based out in Qingdao, China. It is known for research contribution in the topics: Population & Sea surface temperature. The organization has 27604 authors who have published 27886 publications receiving 440181 citations. The organization is also known as: Zhōngguó Hǎiyáng Dàxué & OUC.
Topics: Population, Sea surface temperature, Sediment, Gene, Bay
Papers published on a yearly basis
Papers
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TL;DR: The bacteria in the anaerobic biofilm on rusted carbon steel immersed in natural seawater were characterized by culturing and molecular biology techniques as mentioned in this paper, and the corrosion mechanism of steel was proposed and its environmental significance.
190 citations
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TL;DR: The results suggested that the activation of antioxidants in M. aeruginosa played an important role to resist the stress from gramine at initial time, and the inactivation of SOD is crucial to the growth inhibition.
190 citations
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TL;DR: A novel application of fucoidan as an anti-MetS functional food is illustrated and new insight is sheds new insight into the mechanism by which unabsorbed polysaccharide exerts a system therapeutic effect.
189 citations
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TL;DR: It is shown that GlcNAcylation enhances the migration/invasion of breast cancer cells in vitro and lung metastasis in vivo and suggests that it might be a potential target for the diagnosis and therapy of Breast cancer.
Abstract: GlcNAcylation, a dynamic posttranslational modification, is involved in a wide range of biological processes and some human diseases. Although there is emerging evidence that some tumor-associated proteins are modified by GlcNAcylation, the role of GlcNAcylation in tumor progression remains unclear. Here, we show that GlcNAcylation enhances the migration/invasion of breast cancer cells in vitro and lung metastasis in vivo. The decrease of cell surface E-cadherin is the molecular mechanism underlying GlcNAcylation-induced breast cancer metastasis. p120 and beta-catenin, but not E-cadherin, are GlcNAcylated; the GlcNAcylation of p120 and beta-catenin might play roles in the decrease of cell surface E-cadherin. Moreover, immunohistochemistry analysis indicated that the global GlcNAcylation level in breast tumor tissues is elevated significantly as compared with that in the corresponding adjacent tissues; further, GlcNAcylation was significantly enhanced in metastatic lymph nodes compared with their corresponding primary tumor tissues. This is the first report to clearly elucidate the roles and mechanisms whereby GlcNAcylation influences the malignant properties of breast cancer cells. These results also suggest that GlcNAcylation might be a potential target for the diagnosis and therapy of breast cancer.
189 citations
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TL;DR: In this article, the authors reviewed recent progress in the study of perforated/slotted breakwaters, with an emphasis on two main groups of such breakwaters: (1) perforators with impermeable back walls, and (2) breakwaters without a back-wall.
189 citations
Authors
Showing all 27836 results
Name | H-index | Papers | Citations |
---|---|---|---|
Guangming Zeng | 146 | 1676 | 100743 |
Bin Wang | 126 | 2226 | 74364 |
Simon A. Wilde | 118 | 390 | 45547 |
Yusuke Yamauchi | 117 | 1000 | 51685 |
Xiaoming Li | 113 | 1932 | 72445 |
Baoshan Xing | 109 | 823 | 48944 |
Peng Wang | 108 | 1672 | 54529 |
Jun Yang | 107 | 2090 | 55257 |
Shang-Ping Xie | 105 | 441 | 36437 |
M. Santosh | 103 | 1344 | 49846 |
Qi Li | 102 | 1563 | 46762 |
Wei Liu | 102 | 2927 | 65228 |
Tao Wang | 97 | 2720 | 55280 |
Wei Wang | 95 | 3544 | 59660 |
Peng Li | 95 | 1548 | 45198 |