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Institution

Ochsner Medical Center

HealthcareNew Orleans, Louisiana, United States
About: Ochsner Medical Center is a healthcare organization based out in New Orleans, Louisiana, United States. It is known for research contribution in the topics: Population & Heart failure. The organization has 980 authors who have published 1159 publications receiving 49961 citations. The organization is also known as: Ochsner Hospital & Ochsner Foundation Hospital.


Papers
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Journal ArticleDOI
TL;DR: This article presents a 25-year experience of management of NTOS patients, at the Louisiana State University Health Sciences Center, which have been divided into 2 subcategories of “disputed NTOS” or “true NTOS.”
Abstract: Neurogenic thoracic outlet syndrome (NTOS) is the most common variant of thoracic outlet syndrome. This article presents a 25-year experience of management of 133 operative NTOS patients, at the Louisiana State University Health Sciences Center, which have been divided into 2 subcategories of “disputed NTOS” or “true NTOS.” The clinical presentations, results of neurologic examinations, radiologic evaluations, operative procedures, intraoperative findings, and nerve action potential results and outcomes of the management are evaluated.

9 citations

Journal ArticleDOI
TL;DR: Observations suggest morphine regulates selective molecular events that manifest in biologically altered immune function including T cell activation and IL-2 production in rhesus monkeys following stimulation with PWM.
Abstract: In the present investigation, infrequent and chronic (daily) exposure of rhesus monkeys to morphine was investigated for their effect on cytokine receptor expression, interleukin (IL)-2 production, and nuclear factor κPB (NFκPB) levels following stimulation with PWM. In a time-dependent manner, peripheral blood mononuclearcells (PBMCs) from both infrequent- and daily-morphine treated monkeys displayed significantly less (40 ± 7%) IL-2 receptor compared to PBMCs from saline-treated controls. However, PBMCs from chronic opioid- and infrequent opioidtreated monkeys displayed similar levels of IL-4 and IL-7 receptors compared to saline-treated animals. Following stimulation with PWM, PBMCs from chronic opioid-treated monkeys produced elevated levels of IL-2 (870 ± 94 pg/ml) compared to IL-2 levels (463 ± 88 pg/ml) of PBMCs from saline-treated monkey. Likewise, PBMCs from chronic-morphine exposed monkeys had elevated levels (43%) of NFκPB compared to PBMCs from saline-treated (control) monkeys following 72 hou...

9 citations

Journal ArticleDOI
TL;DR: The observed MNA necessitates adherence-enhancing interventions encompassing the entire post-heart transplant medication regimen, including immunosuppressants and co-medications.

9 citations

Journal ArticleDOI
TL;DR: In this article, the authors outline the framework for the diagnosis and management of vertebral artery disease with focus on the emerging benefits of angiography and endovascular interventions, which can be treated with angioplasty and stenting with good technical results.

9 citations

Journal ArticleDOI
TL;DR: Three additional children from two unrelated families with cholestasis and liver failure due to pathologic variants in NR1H4 are described, including one patient underwent liver transplantation and has had good clinical outcomes in six years of follow-up.
Abstract: Pathogenic sequence variants in the nuclear bile acid receptor FXR, encoded by NR1H4, have been reported in a small number of children with low-γ-glutamyl transferase (GGT) cholestasis progressing to liver failure. We describe 3 additional children from 2 unrelated families with cholestasis and liver failure because of pathologic variants in NR1H4. One patient underwent liver transplantation and has had good clinical outcomes in 6 years of follow-up. Although that patient has biochemical evidence of increased bile acid synthetic activity, he has not experienced post-transplant diarrhea or allograft steatosis, as has been reported among other transplanted patients.

9 citations


Authors

Showing all 993 results

NameH-indexPapersCitations
Carl J. Lavie106113549318
Michael R. Jaff8244228891
Michael F. O'Rourke8145135355
Mandeep R. Mehra8064431939
Richard V. Milani8045423410
Christopher J. White7762125767
Bruce A. Reitz7433318457
Robert C. Bourge6927324397
Sana M. Al-Khatib6937717370
Hector O. Ventura6647816379
Andrew Mason6336015198
Aaron S. Dumont6038613020
Philip J. Kadowitz5537911951
David W. Dunn541958999
Lydia A. Bazzano5126713581
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20231
202223
2021120
2020117
2019102
201886