scispace - formally typeset
Search or ask a question
Institution

Ochsner Medical Center

HealthcareNew Orleans, Louisiana, United States
About: Ochsner Medical Center is a healthcare organization based out in New Orleans, Louisiana, United States. It is known for research contribution in the topics: Population & Heart failure. The organization has 980 authors who have published 1159 publications receiving 49961 citations. The organization is also known as: Ochsner Hospital & Ochsner Foundation Hospital.


Papers
More filters
Journal ArticleDOI
TL;DR: Clinical utility of MPseq is demonstrated, particularly for characterizing novel gene fusion events which may ultimately identify a false-positive FISH result.

5 citations

Journal ArticleDOI
TL;DR: The glycemic benefits of glargine use compared with alternative therapeutic options are maintained without excess hypoglycemia in patients with CVRFs, as well as with intensification of OADs or lifestyle modifications, overall, and in Patients with any CVRF.
Abstract: Background: Cardiovascular risk factors (CVRFs) may complicate optimization of therapy in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with oral antidiabetes drugs (OADs). We assessed the influence of patient baseline CVRFs on efficacy and rate of hypoglycemia with use of insulin glargine (glargine) added to ongoing OAD treatment compared with alternative therapeutic options; namely, intensification of lifestyle interventions or adding OADs, neutral protamine Hagedorn (NPH), lispro, or premixed insulin in patients failing OADs. Methods: Patient-level data were pooled from 9 randomized controlled trials of glargine and comparators for 24 weeks in insulin-naive patients with T2DM inadequately controlled on OADs. Efficacy (goal attainment—glycated hemoglobin (HbA1c) level ≤ 7.0% or decrease ≥ 1.0% change from baseline) and hypoglycemia rates (symptomatic, confirmed, nocturnal, or severe) were compared for patients treated with glargine (n = 1462) and pooled (n = 1476) and ind...

5 citations

Journal ArticleDOI
TL;DR: In the past several years, there has been a paradigm shift in acute stroke care driven by a series of randomized controlled trials demonstrating that timely reperfusion with mechanical thrombectomy results in superior outcomes compared with intravenous thrombolysis in patients with large vessel.

5 citations

Journal ArticleDOI
TL;DR: When adequate glycemic control is not achieved using OADs in patients with T2DM, initiating insulin glargine is generally less likely to elicit hypoglycemia than initiating NPH, premixed, or prandial insulins, and the benefit–risk balance supports initiating insulin rather than intensification of OAD therapy.
Abstract: Purpose: Optimizing glycemic control in patients with type 2 diabetes mellitus (T2DM) not controlled with ≥ 1 oral antidiabetes drugs (OADs) is challenging. Many therapeutic options exist; however, data comparing the effectiveness of different strategies are lacking for the management of patients with T2DM. Our study aim was to provide comparative data on efficacy and hypoglycemia when initiating insulin glargine (glargine) versus alternative treatment options (not including the newest antidiabetes agents, glucagon-like peptide [GLP]-1 receptor agonists, dipeptidyl peptidase [DPP]-4 inhibitors or sodium-glucose linked transporter [SGLT]-2 inhibitors) in insulin-naive patients with T2DM who remained uncontrolled with OADs. Methods: Patient-level data were pooled from 9 randomized controlled trials of ≥ 24 weeks duration with comparable patient populations. The effect of adding glargine was compared with intensification of lifestyle interventions or OADs, addition of neutral protamine Hagedorn (NPH)...

5 citations

Journal ArticleDOI
TL;DR: Moderate or mild hypothermia is a major cause of morbidity and mortality in North America for individuals below the age of 45 and is classified as a reduction in core temperature to 32–34 degrees C.

5 citations


Authors

Showing all 993 results

NameH-indexPapersCitations
Carl J. Lavie106113549318
Michael R. Jaff8244228891
Michael F. O'Rourke8145135355
Mandeep R. Mehra8064431939
Richard V. Milani8045423410
Christopher J. White7762125767
Bruce A. Reitz7433318457
Robert C. Bourge6927324397
Sana M. Al-Khatib6937717370
Hector O. Ventura6647816379
Andrew Mason6336015198
Aaron S. Dumont6038613020
Philip J. Kadowitz5537911951
David W. Dunn541958999
Lydia A. Bazzano5126713581
Network Information
Related Institutions (5)
Henry Ford Hospital
12.4K papers, 465.3K citations

80% related

Cleveland Clinic
79.3K papers, 3.4M citations

77% related

Cedars-Sinai Medical Center
26.4K papers, 1.2M citations

77% related

Vanderbilt University Medical Center
34.6K papers, 1.1M citations

76% related

Hospital of the University of Pennsylvania
14K papers, 459.9K citations

76% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20231
202223
2021120
2020117
2019102
201886