Ochsner Medical Center

About: Ochsner Medical Center is a healthcare organization based out in New Orleans, Louisiana, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 980 authors who have published 1159 publications receiving 49961 citations. The organization is also known as: Ochsner Hospital & Ochsner Foundation Hospital.

In reply: Impaired myocardial blood flow in atrial fibrillation

Abstract: To the Editor, We thank Cay et al for their interest in our work and we agree that it is important to consider changes in myocardial blood flow (MBF) that may change over time and that may be related to the patient's prevalent heart rhythm. The article cited in the letter examined magnetic resonance imaging‐derived MBF between nonischemic patients with established paroxysmal/persistent atrial fibrillation (AF) and healthy controls recruited via a poster. These two groups showed significant variation in medical therapy, and quite probably comorbidities (though no data on comorbidity were given). As stated in the Letter to the Editor, there was no improvement in MBF among AF patients following ablation resulting in the restoration of sinus rhythm. To our knowledge, there are no well‐matched data showing significant changes in MBF based solely on rhythm. It also is important to note that all patients in our study had atrial fibrillation, and we compared survival among those with occult coronary artery disease (CAD) who were or were not treated with Class 1C antiarrhythmic medication. We were able to identify patients who had CAD based on the relatively novel metric coronary flow capacity (CFC), which differs from global coronary flow reserve (CFR) in that CFC is a pixel‐by‐pixel based metric that combines rest MBF, stress MBF, and CFR into an integrated measurement of CAD severity. We refer the interested reader to references 6 through 9 of our JCE paper, as well as our examination of the impact of revascularization on myocardial blood flow, for further definition, explanation, and examples.

What Is the Role of Nutrition Therapy in the Management of the Adult Cystic Fibrosis Patient

Abstract: Once a death sentence, many patients with cystic fibrosis (CF) are now surviving into their forties and almost half of the current CF population in the USA are over the age of 18 years. Nutritional interventions that are aimed towards maintaining normal weight and prevention of nutritional deficiencies are critical in the management of CF and directly impact pulmonary function and survival. CF is a multisystem disease and several complications can interfere with the ability to ingest food or digest and absorb nutrients. This review investigates various gastrointestinal and endocrine complications that impact nutritional status in CF. Specific nutritional therapies are highlighted ranging from nutritional counseling to enteral and parenteral nutrition with emphasis on pancreatic enzyme replacement therapy and the challenges associated with their use.

Congenital left ventricular diverticulum repair in an adult with dual patch technique.

Abstract: Rupture of a congenital left ventricular diverticulum (CLVD), a rare anatomical anomaly, is a catastrophic event, with potential fatal consequences. Repair techniques documented in the literature include primary closure and single patch closure. We describe a case of a 57-year-old woman with symptomatic anterolateral CLVD. Our approach involves a linear incision through the epicardial surface of the diverticulum with exclusion of the cavity, and restoration of normal ventricular geometry via a two-patch technique.

A single-center retrospective analysis of the effect of Radium-223 (Xofigo) on pancytopenia in patients with metastatic castration-resistant prostate cancer.

Abstract: e16546Background: Radium-223 (Xofigo) has been shown to increase overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC) via the phase 3 ALSYMPCA study. The s...