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Institution

Ohio State University

EducationColumbus, Ohio, United States
About: Ohio State University is a education organization based out in Columbus, Ohio, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 102421 authors who have published 222715 publications receiving 8373403 citations. The organization is also known as: Ohio State & The Ohio State University.


Papers
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Journal ArticleDOI
TL;DR: An experimental system is described in which certain features called moment invariants are extracted from binary television images and are used for automatic classification of aircraft types from optical images, exhibiting a significantly lower error rate than human observers.
Abstract: Although many systems for optical reading of printed matter have been developed and are now in wide use, comparatively little success has been achieved in the automatic interpretation of optical images of three-dimensional scenes. This paper is addressed to the latter problem and is specifically concerned with automatic recognition of aircraft types from optical images. An experimental system is described in which certain features called moment invariants are extracted from binary television images and are then used for automatic classification. This experimental system has exhibited a significantly lower error rate than human observers in a limited laboratory test involving 132 images of six aircraft types. Preliminary indications are that this performance can be extended to a wider class of objects and that identification can be accomplished in one second or less with a small computer.

800 citations

Journal ArticleDOI
TL;DR: In this article, the ultimate values for compressive strength, Young's modulus, and toughness of cylindrical specimens of unitary aspect ratios and uniform grain-size distributions were extrapolated for hydroxyapatite (HAP) to 70 MPa, 9.2 GPa, and 0.36 J cm(-3).
Abstract: The ultimate values for compressive strength, Young's modulus, and toughness of cylindrical specimens of unitary aspect ratios and uniform grain-size distributions were extrapolated for hydroxyapatite (HAP) to 70 MPa, 9.2 GPa, and 0.36 J cm(-3), and for tricalcium phosphate (TCP), to 315 MPa, 21 GPa, and 2.34 J cm(-3). For total volume porosities of 50%, the corresponding values were determined: for HAP, 9.3 MPa, 1.2 GPa, 0.042 J cm(-3), for TCP, 13 MPa, 1.6 GP, 0.077 J cm(-3). Porosities of HAP specimens ranged from 3%-50%; TCP from 10%-70%. Two pore-size distributions were employed. Exponential dependencies of the mechanical properties were found upon porosity (p < 0.0001). No differences in measured mechanical properties, as determined in compression, could be attributed to pore size. The superiority of TCP increases with density and suggests that a larger or more selective pore-size distribution could be effectively employed in TCP biological implants. This work also suggests the dominant role of secondary calcium phosphates in increasing compressive strengths.

798 citations

Journal ArticleDOI
18 Jan 2018
TL;DR: Cachexia is a disorder characterized by loss of body weight with specific losses of skeletal muscle and adipose tissue as mentioned in this paper, which is associated with cancers of the pancreas, oesophagus, stomach, lung, liver and bowel.
Abstract: Cancer-associated cachexia is a disorder characterized by loss of body weight with specific losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination of reduced food intake and metabolic changes, including elevated energy expenditure, excess catabolism and inflammation. Cachexia is highly associated with cancers of the pancreas, oesophagus, stomach, lung, liver and bowel; this group of malignancies is responsible for half of all cancer deaths worldwide. Cachexia involves diverse mediators derived from the cancer cells and cells within the tumour microenvironment, including inflammatory and immune cells. In addition, endocrine, metabolic and central nervous system perturbations combine with these mediators to elicit catabolic changes in skeletal and cardiac muscle and adipose tissue. At the tissue level, mechanisms include activation of inflammation, proteolysis, autophagy and lipolysis. Cachexia associates with a multitude of morbidities encompassing functional, metabolic and immune disorders as well as aggravated toxicity and complications of cancer therapy. Patients experience impaired quality of life, reduced physical, emotional and social well-being and increased use of healthcare resources. To date, no effective medical intervention completely reverses cachexia and there are no approved drug therapies. Adequate nutritional support remains a mainstay of cachexia therapy, whereas drugs that target overactivation of catabolic processes, cell injury and inflammation are currently under investigation.

798 citations

Journal ArticleDOI
TL;DR: The authors argue that country attributes are still critical to financial decision-making because of "twin agency problems" that arise because rulers of sovereign states and corporate insiders pursue their own interests at the expense of outside investors.
Abstract: Despite the dramatic reduction in explicit barriers to international investment activity over the last 60 years, the impact of financial globalization has been surprisingly limited. I argue that country attributes are still critical to financial decision-making because of “twin agency problems” that arise because rulers of sovereign states and corporate insiders pursue their own interests at the expense of outside investors. When these twin agency problems are significant, diffuse ownership is inefficient and corporate insiders must co-invest with other investors, retaining substantial equity. The resulting ownership concentration limits economic growth, financial development, and the ability of a country to take advantage of financial globalization.

798 citations

Journal ArticleDOI
J. Abraham1, P. Abreu2, Marco Aglietta3, C. Aguirre  +449 moreInstitutions (69)
09 Nov 2007-Science
TL;DR: In this article, the authors demonstrate that there is a correlation between the arrival directions of cosmic rays with energy above 6 x 10{sup 19} eV and the positions of active galactic nuclei lying within 75 Mpc.
Abstract: Using data collected at the Pierre Auger Observatory during the past 3.7 years, we demonstrate that there is a correlation between the arrival directions of cosmic rays with energy above {approx} 6 x 10{sup 19} eV and the positions of active galactic nuclei (AGN) lying within {approx} 75 Mpc. We reject the hypothesis of an isotropic distribution of these cosmic rays at over 99% confidence level from a prescribed a priori test. The correlation we observe is compatible with the hypothesis that the highest energy particles originate from nearby extragalactic sources whose flux has not been significantly reduced by interaction with the cosmic background radiation. AGN or objects having a similar spatial distribution are possible sources.

798 citations


Authors

Showing all 103197 results

NameH-indexPapersCitations
Paul M. Ridker2331242245097
George Davey Smith2242540248373
Carlo M. Croce1981135189007
Eric J. Topol1931373151025
Bernard Rosner1901162147661
David H. Weinberg183700171424
Anil K. Jain1831016192151
Michael I. Jordan1761016216204
Kay-Tee Khaw1741389138782
Richard K. Wilson173463260000
Yang Yang1642704144071
Brian L Winer1621832128850
Jian-Kang Zhu161550105551
Elaine R. Mardis156485226700
R. E. Hughes1541312110970
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023261
20221,234
20219,945
20209,944
20199,052
20188,656