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Institution

Ohio State University

EducationColumbus, Ohio, United States
About: Ohio State University is a education organization based out in Columbus, Ohio, United States. It is known for research contribution in the topics: Population & Cancer. The organization has 102421 authors who have published 222715 publications receiving 8373403 citations. The organization is also known as: Ohio State & The Ohio State University.


Papers
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Journal ArticleDOI
18 Jun 2009-Blood
TL;DR: Novel functional links between miRNAs and aberrant DNA hypermethylation in acute myeloid leukemia and suggest a potentially therapeutic use of synthetic miR-29b oligonucleotides as effective hypomethylating compounds are provided.

748 citations

Journal ArticleDOI
TL;DR: The authors reviewed the empirical research and theoretical perspectives on gender inequalities in educational performance and attainment from early childhood to young adulthood and recommended three directions for future research: (a) interdisciplinary efforts to understand gender differences in cognitive development and noncognitive abilities in early childhood, (b) research on the structure and practices of schooling, and (c) analyses of how gender differences might amplify other kinds of inequalities, such as racial, ethnic, class, or nativity inequalities.
Abstract: The terrain of gender inequalities in education has seen much change in recent decades. This article reviews the empirical research and theoretical perspectives on gender inequalities in educational performance and attainment from early childhood to young adulthood. Much of the literature on children and adolescents attends to performance differences between girls and boys. Of course, achievement in elementary and secondary school is linked to the level of education one ultimately attains including high school completion, enrollment in postsecondary education, college completion, and graduate and professional school experiences. We recommend three directions for future research: (a) interdisciplinary efforts to understand gender differences in cognitive development and noncognitive abilities in early childhood, (b) research on the structure and practices of schooling, and (c) analyses of how gender differences might amplify other kinds of inequalities, such as racial, ethnic, class, or nativity inequalities.

748 citations

Book ChapterDOI
TL;DR: In this article, a subjective scaling approach, the Subjective Workload Assessment Technique (SWAT), is proposed to capture the multidimensional nature of mental workload, which can be largely explained by three component factors: Time Load, Mental Effort Load, and Psychological Stress Load.
Abstract: Mental workload is proposed to be a multidimensional construct that can be largely explained by three component factors: Time Load, Mental Effort Load, and Psychological Stress Load. In this paper, we describe a subjective scaling approach, the Subjective Workload Assessment Technique (SWAT), that captures this multidimensional nature of mental workload. We describe the SWAT procedure as a two-phased method that includes (a) a scale development phase based on conjoint measurement and nonmetric scaling, and (b) an event scoring phase. The development of SWAT and its measurement foundations are discussed. Recent research illustrating SWAT's widespread utility and its sensitivity as a measure of perceived mental workload is summarized.

748 citations

Journal ArticleDOI
TL;DR: The obstructions to the existence of a graph are studied to find a minimax formula relating tree-width with the largest such obstructions and a “tree-decomposition” of the graph into pieces corresponding with the obstructions.

748 citations

Journal ArticleDOI
TL;DR: Radiotherapy is a successful and time efficient method by which to palliate pain and/or prevent the morbidity of bone metastases and is recommended for surgical decompression and postoperative radiotherapy in highly selected patients with sufficient performance status and life expectancy.
Abstract: Purpose To present guidance for patients and physicians regarding the use of radiotherapy in the treatment of bone metastases according to current published evidence and complemented by expert opinion. Methods and Materials A systematic search of the National Library of Medicine’s PubMed database between 1998 and 2009 yielded 4,287 candidate original research articles potentially applicable to radiotherapy for bone metastases. A Task Force composed of all authors synthesized the published evidence and reached a consensus regarding the recommendations contained herein. Results The Task Force concluded that external beam radiotherapy continues to be the mainstay for the treatment of pain and/or prevention of the morbidity caused by bone metastases. Various fractionation schedules can provide significant palliation of symptoms and/or prevent the morbidity of bone metastases. The evidence for the safety and efficacy of repeat treatment to previously irradiated areas of peripheral bone metastases for pain was derived from both prospective studies and retrospective data, and it can be safe and effective. The use of stereotactic body radiotherapy holds theoretical promise in the treatment of new or recurrent spine lesions, although the Task Force recommended that its use be limited to highly selected patients and preferably within a prospective trial. Surgical decompression and postoperative radiotherapy is recommended for spinal cord compression or spinal instability in highly selected patients with sufficient performance status and life expectancy. The use of bisphosphonates, radionuclides, vertebroplasty, and kyphoplasty for the treatment or prevention of cancer-related symptoms does not obviate the need for external beam radiotherapy in appropriate patients. Conclusions Radiotherapy is a successful and time efficient method by which to palliate pain and/or prevent the morbidity of bone metastases. This Guideline reviews the available data to define its proper use and provide consensus views concerning contemporary controversies or unanswered questions that warrant prospective trial evaluation.

747 citations


Authors

Showing all 103197 results

NameH-indexPapersCitations
Paul M. Ridker2331242245097
George Davey Smith2242540248373
Carlo M. Croce1981135189007
Eric J. Topol1931373151025
Bernard Rosner1901162147661
David H. Weinberg183700171424
Anil K. Jain1831016192151
Michael I. Jordan1761016216204
Kay-Tee Khaw1741389138782
Richard K. Wilson173463260000
Yang Yang1642704144071
Brian L Winer1621832128850
Jian-Kang Zhu161550105551
Elaine R. Mardis156485226700
R. E. Hughes1541312110970
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023261
20221,236
20219,948
20209,945
20199,052
20188,656