Institution
Ohio State University
Education•Columbus, Ohio, United States•
About: Ohio State University is a education organization based out in Columbus, Ohio, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 102421 authors who have published 222715 publications receiving 8373403 citations. The organization is also known as: Ohio State & The Ohio State University.
Topics: Population, Poison control, Galaxy, Cancer, Breast cancer
Papers published on a yearly basis
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TL;DR: The approach is general because it offers the definition, identification, estimation, and sensitivity analysis of causal mediation effects without reference to any specific statistical model and can accommodate linear and nonlinear relationships, parametric and nonparametric models, continuous and discrete mediators, and various types of outcome variables.
Abstract: Traditionally in the social sciences, causal mediation analysis has been formulated, understood, and implemented within the framework of linear structural equation models. We argue and demonstrate that this is problematic for 3 reasons: the lack of a general definition of causal mediation effects independent of a particular statistical model, the inability to specify the key identification assumption, and the difficulty of extending the framework to nonlinear models. In this article, we propose an alternative approach that overcomes these limitations. Our approach is general because it offers the definition, identification, estimation, and sensitivity analysis of causal mediation effects without reference to any specific statistical model. Further, our approach explicitly links these 4 elements closely together within a single framework. As a result, the proposed framework can accommodate linear and nonlinear relationships, parametric and nonparametric models, continuous and discrete mediators, and various types of outcome variables. The general definition and identification result also allow us to develop sensitivity analysis in the context of commonly used models, which enables applied researchers to formally assess the robustness of their empirical conclusions to violations of the key assumption. We illustrate our approach by applying it to the Job Search Intervention Study. We also offer easy-to-use software that implements all our proposed methods.
2,393 citations
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Johns Hopkins University1, University of Michigan2, University of Texas MD Anderson Cancer Center3, Georgetown University4, The Royal Marsden NHS Foundation Trust5, Roswell Park Cancer Institute6, Oncology Nursing Society7, University of Washington8, Memorial Sloan Kettering Cancer Center9, Harvard University10, University of Oklahoma11, American Society of Clinical Oncology12, New York University13, Ohio State University14
TL;DR: Recommendations for specific organ system-based toxicity diagnosis and management are presented and, in general, permanent discontinuation of ICPis is recommended with grade 4 toxicities, with the exception of endocrinopathies that have been controlled by hormone replacement.
Abstract: PurposeTo increase awareness, outline strategies, and offer guidance on the recommended management of immune-related adverse events in patients treated with immune checkpoint inhibitor (ICPi) therapyMethodsA multidisciplinary, multi-organizational panel of experts in medical oncology, dermatology, gastroenterology, rheumatology, pulmonology, endocrinology, urology, neurology, hematology, emergency medicine, nursing, trialist, and advocacy was convened to develop the clinical practice guideline Guideline development involved a systematic review of the literature and an informal consensus process The systematic review focused on guidelines, systematic reviews and meta-analyses, randomized controlled trials, and case series published from 2000 through 2017ResultsThe systematic review identified 204 eligible publications Much of the evidence consisted of systematic reviews of observational data, consensus guidelines, case series, and case reports Due to the paucity of high-quality evidence on management
2,386 citations
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TL;DR: In this paper, the authors studied the dark-matter halo density profiles in a high-resolution N-body simulation of a CDM cosmology and found that the redshift dependence of the median concentration is cvirRvir/rs.
Abstract: We study dark-matter halo density profiles in a high-resolution N-body simulation of aCDM cosmology. Our statistical sample contains �5000 haloes in the range 10 11 10 14 h −1 M⊙ and the resolution allows a study of subhaloes inside host haloes. The profiles are parameterized by an NFW form with two parameters, an inner radius rs and a virial radius Rvir, and we define the halo concentration cvirRvir/rs. We find that, for a given halo mass, the redshift dependence of the median concentration is cvir / (1 + z) −1 . This corresponds to rs(z) � constant, and is contrary to earlier suspicions that cvir does not vary much with redshift. The implications are that high- redshift galaxies are predicted to be more extended and dimmer than expected before. Second, we find that the scatter in halo profiles is large, with a 1� �(logcvir) = 0.18 at a given mass, corresponding to a scatter in maximum rotation velocities of �Vmax/Vmax = 0.12. We discuss implications for modelling the Tully-Fisher relation, which has a smaller reported intrinsic scatter. Third, subhaloes and haloes in dense environments tend to be more concentrated than isolated haloes, and show a larger scatter. These results suggest that cvir is an essential parameter for the theory of galaxy modelling, and we briefly discuss implications for the universality of the Tully- Fisher relation, the formation of low surface brightness galaxies, and the origin of the Hubble sequence. We present an improved analytic treatment of halo formation that fits the measured relations between halo parameters and their redshift dependence, and can thus serve semi-analytic studies of galaxy formation.
2,383 citations
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TL;DR: In 1998, the Council of Logistics Management modified its definition of logistics to indicate that logistics is a subset of supply chain management and that the two terms are not synonymous as discussed by the authors.
Abstract: In 1998, the Council of Logistics Management modified its definition of logistics to indicate that logistics is a subset of supply chain management and that the two terms are not synonymous Now that this difference has been recognized by the premier logistics professional organization, the challenge is to determine how to successfully implement supply chain management This paper concentrates on operationalizing the supply chain management framework suggested in a 1997 article Case studies conducted at several companies and involving multiple members of supply chains are used to illustrate the concepts described
2,380 citations
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University of Tasmania1, Woods Hole Oceanographic Institution2, Yale University3, University of California, Santa Barbara4, University of São Paulo5, University of Cape Town6, South Dakota State University7, Columbia University8, California Institute of Technology9, University of Bristol10, University of California, Los Angeles11, United States Geological Survey12, University of California, Berkeley13, Monash University14, Brown University15, Ohio State University16, Royal Holloway, University of London17, University of Arizona18, VU University Amsterdam19, Arizona State University20
TL;DR: What is known and what is needed to develop a holistic understanding of the role of fire in the Earth system are reviewed, particularly in view of the pervasive impact of fires and the likelihood that they will become increasingly difficult to control as climate changes.
Abstract: Fire is a worldwide phenomenon that appears in the geological record soon after the appearance of terrestrial plants. Fire influences global ecosystem patterns and processes, including vegetation distribution and structure, the carbon cycle, and climate. Although humans and fire have always coexisted, our capacity to manage fire remains imperfect and may become more difficult in the future as climate change alters fire regimes. This risk is difficult to assess, however, because fires are still poorly represented in global models. Here, we discuss some of the most important issues involved in developing a better understanding of the role of fire in the Earth system.
2,365 citations
Authors
Showing all 103197 results
Name | H-index | Papers | Citations |
---|---|---|---|
Paul M. Ridker | 233 | 1242 | 245097 |
George Davey Smith | 224 | 2540 | 248373 |
Carlo M. Croce | 198 | 1135 | 189007 |
Eric J. Topol | 193 | 1373 | 151025 |
Bernard Rosner | 190 | 1162 | 147661 |
David H. Weinberg | 183 | 700 | 171424 |
Anil K. Jain | 183 | 1016 | 192151 |
Michael I. Jordan | 176 | 1016 | 216204 |
Kay-Tee Khaw | 174 | 1389 | 138782 |
Richard K. Wilson | 173 | 463 | 260000 |
Yang Yang | 164 | 2704 | 144071 |
Brian L Winer | 162 | 1832 | 128850 |
Jian-Kang Zhu | 161 | 550 | 105551 |
Elaine R. Mardis | 156 | 485 | 226700 |
R. E. Hughes | 154 | 1312 | 110970 |