Ohio State University

About: Ohio State University is a education organization based out in Columbus, Ohio, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 102421 authors who have published 222715 publications receiving 8373403 citations. The organization is also known as: Ohio State & The Ohio State University.

Nanoscale metal oxide-based heterojunctions for gas sensing: A review

Abstract: Metal oxide-based resistive-type gas sensors are solid-state devices which are widely used in a number of applications from health and safety to energy efficiency and emission control. Nanomaterials such as nanowires, nanorods, and nanoparticles have dominated the research focus in this field due to their large number of surface sites facilitating surface reactions. Previous studies have shown that incorporating two or more metal oxides to form a heterojunction interface can have drastic effects on gas sensor performance, especially the selectivity. Recently, these effects have been amplified by designing heterojunctions on the nano-scale. These designs have evolved from mixed commercial powders and bi-layer films to finely-tuned core–shell and hierarchical brush-like nanocomposites. This review details the various morphological classes currently available for nanostructured metal-oxide based heterojunctions and then presents the dominant electronic and chemical mechanisms that influence the performance of these materials as resistive-type gas sensors. Mechanisms explored include p–n and n–n potential barrier manipulation, n–p–n response type inversions, spill-over effects, synergistic catalytic behavior, and microstructure enhancement. Tables are presented summarizing these works specifically for SnO2, ZnO, TiO2, In2O3, Fe2O3, MoO3, Co3O4, and CdO-based nanocomposites. Recent developments are highlighted and likely future trends are explored.

Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma

Abstract: rolled into two groups: those who had previously received at least 2 cycles of bor - tezomib therapy and those who had received less than 2 complete cycles of bortezo - mib or had received no prior bortezomib therapy. The primary end point was the overall response rate. Secondary end points were duration of response, progression- free survival, overall survival, and safety. RESULTS The median age was 68 years, and 86% of patients had intermediate-risk or high-risk mantle-cell lymphoma according to clinical prognostic factors. Patients had received a median of three prior therapies. The most common treatment-related adverse events were mild or moderate diarrhea, fatigue, and nausea. Grade 3 or higher hematologic events were infrequent and included neutropenia (in 16% of patients), thrombocytope - nia (in 11%), and anemia (in 10%). A response rate of 68% (75 patients) was observed, with a complete response rate of 21% and a partial response rate of 47%; prior treat - ment with bortezomib had no effect on the response rate. With an estimated median follow-up of 15.3 months, the estimated median response duration was 17.5 months (95% confidence interval (CI), 15.8 to not reached), the estimated median progression- free survival was 13.9 months (95% CI, 7.0 to not reached), and the median overall survival was not reached. The estimated rate of overall survival was 58% at 18 months. CONCLUSIONS Ibrutinib shows durable single-agent efficacy in relapsed or refractory mantle-cell lymphoma. (Funded by Pharmacyclics and others; ClinicalTrials.gov number, NCT01236391.)

Heart rate variability, prefrontal neural function, and cognitive performance: the neurovisceral integration perspective on self-regulation, adaptation, and health.

Abstract: In the present paper, we describe a model of neurovisceral integration in which a set of neural structures involved in cognitive, affective, and autonomic regulation are related to heart rate variability (HRV) and cognitive performance. We detail the pathways involved in the neural regulation of the cardiovascular system and provide pharmacological and neuroimaging data in support of the neural structures linking the central nervous system to HRV in humans. We review a number of studies from our group showing that individual differences in HRV are related to performance on tasks associated with executive function and prefrontal cortical activity. These studies include comparisons of executive- and nonexecutive-function tasks in healthy participants, in both threatening and nonthreatening conditions. In addition, we show that manipulating resting HRV levels is associated with changes in performance on executive-function tasks. We also examine the relationship between HRV and cognitive performance in ecologically valid situations using a police shooting simulation and a naval navigation simulation. Finally, we review our studies in anxiety patients, as well as studies examining psychopathy. These findings in total suggest an important relationship among cognitive performance, HRV, and prefrontal neural function that has important implications for both physical and mental health. Future studies are needed to determine exactly which executive functions are associated with individual differences in HRV in a wider range of situations and populations.

Introduction to Tribology

Abstract: Foreword. Preface. 1 Introduction. 1.1 De.nition and History of Tribology. 1.2 Industrial Signi.cance of Tribology. 1.3 Origins and Signi.cance of Micro/Nanotribology. 1.4 Organization of the Book. References. 2 Solid Surface Characterization. 2.1 The Nature of Surfaces. 2.2 Physico-Chemical Characteristics of Surface Layers. 2.3 Analysis of Surface Roughness. 2.4 Measurement of Surface Roughness. 2.5 Closure. References. Suggested Reading. 3 Contact between Solid Surfaces. 3.1 Introduction. 3.2 Analysis of the Contacts. 3.3 Measurement of the Real Area of Contact. 3.4 Closure. References. Suggested Reading. 4 Adhesion. 4.1 Introduction. 4.2 Solid-Solid Contact. 4.3 Liquid-Mediated Contact. 4.4 Closure. References. Suggested Reading. 5 Friction. 5.1 Introduction. 5.2 Solid-Solid Contact. 5.3 Liquid-Mediated Contact. 5.4 Friction of Materials. 5.5 Closure. References. Suggested Reading. 6 Interface Temperature of Sliding Surfaces. 6.1 Introduction. 6.2 Thermal Analysis. 6.3 Interface Temperature Measurements. 6.4 Closure. References. 7 Wear. 7.1 Introduction. 7.2 Types of Wear Mechanisms. 7.3 Types of Particles Present in Wear Debris. 7.4 Wear of Materials. 7.5 Closure. References. Suggested Reading. 8 Fluid Film Lubrication. 8.1 Introduction. 8.2 Regimes of Fluid Film Lubrication. 8.3 Viscous Flow and Reynolds Equation. 8.4 Hydrostatic Lubrication. 8.5 Hydrodynamic Lubrication. 8.6 Elastohydrodynamic Lubrication. 8.7 Closure. References. Suggested Reading. 9 Boundary Lubrication and Lubricants. 9.1 Introduction. 9.2 Boundary Lubrication. 9.3 Liquid Lubricants. 9.4 Greases. 9.5 Closure. References. Suggested Reading. 10 Micro/Nanotribology. 10.1 Introduction. 10.2 SFA Studies. 10.3 AFM/FFM. 10.4 Atomic-Scale Simulations. 10.5 Closure. References. Suggested Reading. 11 Friction and Wear Screening Test Methods. 11.1 Introduction. 11.2 Design Methodology. 11.3 Typical Test Geometries. 11.4 Closure. References. Suggested Reading. 12Tribological Components and Applications. 12.1 Introduction. 12.2 Common Tribological Components. 12.3 Microcomponents. 12.4 Material Processing. 12.5 Industrial Applications. 12.6 Closure. References. Suggested Reading. Problems. Appendix Units, Conversions, and Useful Relations. A.1 Fundamental Constants. A.2 Conversion of Units. A.3 Useful Relations. Index.