Institution
Ontario Ministry of Health and Long-Term Care
Government•Toronto, Ontario, Canada•
About: Ontario Ministry of Health and Long-Term Care is a government organization based out in Toronto, Ontario, Canada. It is known for research contribution in the topics: Health care & Population. The organization has 609 authors who have published 658 publications receiving 23298 citations.
Topics: Health care, Population, Public health, Outbreak, Health administration
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the authors describe a filamentous bacterium (actinomycete) of the genus Streptomyces that produces antibiotics specifically targeted to suppress the growth of the specialized garden-parasite Escovopsis.
Abstract: The well-studied, ancient and highly evolved mutualism between fungus-growing ants and their fungi has become a model system in the study of symbiosis1,5. Although it is thought at present to involve only two symbionts, associated with each other in near isolation from other organisms1,5, the fungal gardens of attine ants are in fact host to a specialized and virulent parasitic fungus of the genus Escovopsis (Ascomycotina)6. Because the ants and their fungi are mutually dependent, the maintenance of stable fungal monocultures in the presence of weeds or parasites is critical to the survival of both organisms. Here we describe a new, third mutualist in this symbiosis, a filamentous bacterium (actinomycete) of the genus Streptomyces that produces antibiotics specifically targeted to suppress the growth of the specialized garden-parasite Escovopsis. This third mutualist is associated with all species of fungus-growing ants studied, is carried upon regions of the ants' cuticle that are genus specific, is transmitted vertically (from parent to offspring colonies), and has the capacity to promote the growth of the fungal mutualist, indicating that the association of Streptomyces with attine ants is both highly evolved and of ancient origin.
700 citations
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TL;DR: The results were consistent with the polyneuropathy being due to the same mechanisms that are currently postulated to cause dysfunction in this syndrome of other organ systems (including the neuromuscular respiratory system).
536 citations
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Canadian Science Centre for Human and Animal Health1, Defence Research and Development Canada2, Public Health Agency of Canada3, Toronto Public Health4, North York General Hospital5, University of Toronto6, Mount Sinai Hospital7, Women's College, Kolkata8, Toronto East General Hospital9, Ontario Ministry of Health and Long-Term Care10
TL;DR: These data provide the first experimental confirmation of viral aerosol generation by a patient with SARS, indicating the possibility of airborne droplet transmission, which emphasizes the need for adequate respiratory protection, as well as for strict surface hygiene practices.
Abstract: Severe acute respiratory syndrome (SARS) is characterized by a risk of nosocomial transmission; however, the risk of airborne transmission of SARS is unknown. During the Toronto outbreaks of SARS, we investigated environmental contamination in SARS units, by employing novel air sampling and conventional surface swabbing. Two polymerase chain reaction (PCR)-positive air samples were obtained from a room occupied by a patient with SARS, indicating the presence of the virus in the air of the room. In addition, several PCR-positive swab samples were recovered from frequently touched surfaces in rooms occupied by patients with SARS (a bed table and a television remote control) and in a nurses' station used by staff (a medication refrigerator door). These data provide the first experimental confirmation of viral aerosol generation by a patient with SARS, indicating the possibility of airborne droplet transmission, which emphasizes the need for adequate respiratory protection, as well as for strict surface hygiene practices.
403 citations
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TL;DR: A predictive, non-experimental survey design was used to test a theoretical model in a sample of new graduate nurses, and it was predicted that structural empowerment had a direct positive effect on the areas of work life, which in turn had adirect negative effect on emotional exhaustion.
Abstract: As a large cohort of experienced nurses approaches retirement, it is critical to examine factors that will promote the engagement and empowerment of the newer workforce, allowing them to provide high quality patient care. The authors used a predictive, non-experimental survey design to test a theoretical model in a sample of new graduate nurses. More specifically, the relationships among structural empowerment, six areas of work life (conceptualized as antecedents of work engagement), emotional exhaustion and organizational commitment were examined. As predicted, structural empowerment had a direct positive effect on the areas of work life, which in turn had a direct negative effect on emotional exhaustion. Subsequently, emotional exhaustion had a direct negative effect on commitment. Implications of these findings for nursing administrators are discussed.
312 citations
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TL;DR: A hand therapy clinic used a systematic process to select an outcome tool for routine use and unanimously selected the PRWHE with a supplemental esthetics question to be routinely used in measurement of outcomes.
291 citations
Authors
Showing all 609 results
Name | H-index | Papers | Citations |
---|---|---|---|
Gordon H. Guyatt | 231 | 1620 | 228631 |
Deborah J. Cook | 173 | 907 | 148928 |
Steven G. Deeks | 131 | 647 | 61634 |
Gideon Koren | 129 | 1994 | 81718 |
Allison McGeer | 97 | 622 | 37255 |
Donald E. Low | 88 | 359 | 24384 |
James T. Rutka | 84 | 618 | 30391 |
Paul C. Hébert | 80 | 355 | 34112 |
Robert S. McKelvie | 77 | 312 | 21704 |
Truls Østbye | 72 | 555 | 21225 |
Joy C. MacDermid | 72 | 658 | 20568 |
Stephen G. Pauker | 70 | 269 | 23206 |
Pamela J. Goodwin | 67 | 226 | 18069 |
Neil H. Shear | 67 | 443 | 17172 |
Douglas W. Zochodne | 67 | 298 | 14537 |