Institution
Osaka University
Education•Osaka, Japan•
About: Osaka University is a education organization based out in Osaka, Japan. It is known for research contribution in the topics: Laser & Population. The organization has 83778 authors who have published 185669 publications receiving 5158122 citations. The organization is also known as: Ōsaka daigaku.
Topics: Laser, Population, Catalysis, Thin film, Gene
Papers published on a yearly basis
Papers
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TL;DR: This version of MAFFT has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update.
Abstract: We report a major update of the MAFFT multiple sequence alignment program. This version has several new features, including options for adding unaligned sequences into an existing alignment, adjustment of direction in nucleotide alignment, constrained alignment and parallel processing, which were implemented after the previous major update. This report shows actual examples to explain how these features work, alone and in combination. Some examples incorrectly aligned by MAFFT are also shown to clarify its limitations. We discuss how to avoid misalignments, and our ongoing efforts to overcome such limitations.
27,771 citations
TL;DR: The present paper gives a detailed account of the investigations on rabbit liver microsomes and crude microsomal digests, which have led to postulate the hemoprotein nature of the pigment.
11,895 citations
TL;DR: New insights into innate immunity are changing the way the way the authors think about pathogenesis and the treatment of infectious diseases, allergy, and autoimmunity.
10,685 citations
TL;DR: In this article, a search for the Standard Model Higgs boson in proton-proton collisions with the ATLAS detector at the LHC is presented, which has a significance of 5.9 standard deviations, corresponding to a background fluctuation probability of 1.7×10−9.
9,282 citations
TL;DR: Rapid progress that has recently improved the understanding of the molecular mechanisms that mediate TLR signalling is reviewed.
Abstract: One of the mechanisms by which the innate immune system senses the invasion of pathogenic microorganisms is through the Toll-like receptors (TLRs), which recognize specific molecular patterns that are present in microbial components. Stimulation of different TLRs induces distinct patterns of gene expression, which not only leads to the activation of innate immunity but also instructs the development of antigen-specific acquired immunity. Here, we review the rapid progress that has recently improved our understanding of the molecular mechanisms that mediate TLR signalling.
7,906 citations
Authors
Showing all 84130 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Prashant V. Kamat | 140 | 725 | 79259 |
| Wei Huang | 139 | 2417 | 93522 |
| Marco Colonna | 139 | 512 | 71166 |
| Kazunori Kataoka | 138 | 908 | 70412 |
| David A. Jackson | 136 | 1095 | 68352 |
| Ruben C. Gur | 136 | 741 | 61312 |
| M. I. Martínez | 134 | 1251 | 79885 |
| Hector F. DeLuca | 133 | 1303 | 69395 |
| Kohei Yorita | 131 | 1389 | 91177 |
| Masashi Yanagisawa | 130 | 524 | 83631 |
| Kazunori Hanagaki | 129 | 1126 | 82899 |
| Masaharu Nomachi | 129 | 1097 | 81488 |
| Kiyoshi Takeda | 129 | 416 | 109817 |
| Eduardo Marbán | 129 | 579 | 49586 |
| David A. Hafler | 128 | 558 | 64314 |